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P48481

- PP12_ACEPE

UniProt

P48481 - PP12_ACEPE

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Protein
Serine/threonine-protein phosphatase PP1 isozyme 2
Gene
N/A
Organism
Acetabularia peniculus (Green alga) (Polyphysa peniculus)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi61 – 611Manganese 1 By similarity
Metal bindingi63 – 631Manganese 1 By similarity
Metal bindingi89 – 891Manganese 1 By similarity
Metal bindingi89 – 891Manganese 2 By similarity
Metal bindingi121 – 1211Manganese 2 By similarity
Active sitei122 – 1221Proton donor By similarity
Metal bindingi170 – 1701Manganese 2 By similarity
Metal bindingi245 – 2451Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP1 isozyme 2 (EC:3.1.3.16)
OrganismiAcetabularia peniculus (Green alga) (Polyphysa peniculus)
Taxonomic identifieri35862 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeChlorophytaUlvophyceaeDasycladalesPolyphysaceaeAcetabularia

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 319319Serine/threonine-protein phosphatase PP1 isozyme 2
PRO_0000058796Add
BLAST

Proteomic databases

PRIDEiP48481.

Structurei

3D structure databases

ProteinModelPortaliP48481.
SMRiP48481. Positions 3-305.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P48481-1 [UniParc]FASTAAdd to Basket

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MEESAVDDVI ERLLEVRNNR PGKQVNLAEG EIRQLCLTAK DVFMSQPNLL    50
ELEAPIKICG DIHGQYTDLL RLFEYGGFPP EANYLFLGDY VDRGKQSLET 100
ICLLLAFKVK YPKNFFLLRG NHECASINRI YGFYDVCKRR YNIRLWKTFT 150
DCFNCLPACA LVDEKIICMH GGLSPELKSL DAIRHIPRPT DVPDTGLLCD 200
LLWSDPDKDV AGWGENDRGV SYTFGPDTVT GFLQKHDLDL ICRAHQVVED 250
GYEFFAKRQL VTLFSAPNYC GEFDNAGALM SVDDTLMCSF QILKPSEKKG 300
KLLYGSGALA GPGRGTPRR 319
Length:319
Mass (Da):35,924
Last modified:February 1, 1996 - v1
Checksum:i2725A2668FB4BA14
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z28632 Genomic DNA. Translation: CAA82264.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z28632 Genomic DNA. Translation: CAA82264.1 .

3D structure databases

ProteinModelPortali P48481.
SMRi P48481. Positions 3-305.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P48481.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.60.21.10. 1 hit.
InterProi IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view ]
Pfami PF00149. Metallophos. 1 hit.
[Graphical view ]
PRINTSi PR00114. STPHPHTASE.
SMARTi SM00156. PP2Ac. 1 hit.
[Graphical view ]
SUPFAMi SSF56300. SSF56300. 1 hit.
PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Protein phosphatase 2A, a potential regulator of actin dynamics and actin-based organelle motility in the green alga Acetabularia."
    Menzel D., Vugrek O., Frank S., Elsner-Menzel C.
    Eur. J. Cell Biol. 67:179-187(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiPP12_ACEPE
AccessioniPrimary (citable) accession number: P48481
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: June 11, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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