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P48480

- PP11_ACEPE

UniProt

P48480 - PP11_ACEPE

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Protein
Serine/threonine-protein phosphatase PP1 isozyme 1
Gene
N/A
Organism
Acetabularia peniculus (Green alga) (Polyphysa peniculus)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi61 – 611Manganese 1 By similarity
Metal bindingi63 – 631Manganese 1 By similarity
Metal bindingi89 – 891Manganese 1 By similarity
Metal bindingi89 – 891Manganese 2 By similarity
Metal bindingi121 – 1211Manganese 2 By similarity
Active sitei122 – 1221Proton donor By similarity
Metal bindingi170 – 1701Manganese 2 By similarity
Metal bindingi245 – 2451Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein phosphatase PP1 isozyme 1 (EC:3.1.3.16)
    OrganismiAcetabularia peniculus (Green alga) (Polyphysa peniculus)
    Taxonomic identifieri35862 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeChlorophytaUlvophyceaeDasycladalesPolyphysaceaeAcetabularia

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 319319Serine/threonine-protein phosphatase PP1 isozyme 1
    PRO_0000058795Add
    BLAST

    Proteomic databases

    PRIDEiP48480.

    Structurei

    3D structure databases

    ProteinModelPortaliP48480.
    SMRiP48480. Positions 3-306.

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    Gene3Di3.60.21.10. 1 hit.
    InterProiIPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view]
    PfamiPF00149. Metallophos. 1 hit.
    [Graphical view]
    PRINTSiPR00114. STPHPHTASE.
    SMARTiSM00156. PP2Ac. 1 hit.
    [Graphical view]
    SUPFAMiSSF56300. SSF56300. 1 hit.
    PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P48480-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDESTVDDVI ERLLEVRNNR PGKQVQLTES EIRLLCLTSK EILSEQPNLL    50
    ELEAPIKICG DIHGQYTDLL RLFEYGGFPP EANYLFLGDY VDRGKQSLET 100
    ICLLLAFKIK YPENFFILRG NHECASINRI YGFYDECKRR YNIRLWKTFT 150
    DCFNCLPVAA IVDEKILCMH GGLSPELKTL EQIRRIPRPT DVPDTGLLCD 200
    LLWADPDKDV QGWGENDRGV SYTFGPDTVT EFLQRHDLDL VCRAHQVVED 250
    GYEFFAKRQL VTLFSAPNYC GEFDNAGALM SVDDTLMCSF QILKPSEKKG 300
    KFMQGGNSLA GAGRGTPRR 319
    Length:319
    Mass (Da):36,313
    Last modified:February 1, 1996 - v1
    Checksum:i80696B708B768E22
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z28627 Genomic DNA. Translation: CAA82263.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z28627 Genomic DNA. Translation: CAA82263.1 .

    3D structure databases

    ProteinModelPortali P48480.
    SMRi P48480. Positions 3-306.
    ModBasei Search...

    Proteomic databases

    PRIDEi P48480.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.60.21.10. 1 hit.
    InterProi IPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view ]
    Pfami PF00149. Metallophos. 1 hit.
    [Graphical view ]
    PRINTSi PR00114. STPHPHTASE.
    SMARTi SM00156. PP2Ac. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56300. SSF56300. 1 hit.
    PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Protein phosphatase 2A, a potential regulator of actin dynamics and actin-based organelle motility in the green alga Acetabularia."
      Menzel D., Vugrek O., Frank S., Elsner-Menzel C.
      Eur. J. Cell Biol. 67:179-187(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiPP11_ACEPE
    AccessioniPrimary (citable) accession number: P48480
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: June 11, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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