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P48480 (PP11_ACEPE) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein phosphatase PP1 isozyme 1

EC=3.1.3.16
OrganismAcetabularia peniculus (Green alga) (Polyphysa peniculus)
Taxonomic identifier35862 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeChlorophytaUlvophyceaeDasycladalesPolyphysaceaeAcetabularia

Protein attributes

Sequence length319 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PPP phosphatase family. PP-1 subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 319319Serine/threonine-protein phosphatase PP1 isozyme 1
PRO_0000058795

Sites

Active site1221Proton donor By similarity
Metal binding611Manganese 1 By similarity
Metal binding631Manganese 1 By similarity
Metal binding891Manganese 1 By similarity
Metal binding891Manganese 2 By similarity
Metal binding1211Manganese 2 By similarity
Metal binding1701Manganese 2 By similarity
Metal binding2451Manganese 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
P48480 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 80696B708B768E22

FASTA31936,313
        10         20         30         40         50         60 
MDESTVDDVI ERLLEVRNNR PGKQVQLTES EIRLLCLTSK EILSEQPNLL ELEAPIKICG 

        70         80         90        100        110        120 
DIHGQYTDLL RLFEYGGFPP EANYLFLGDY VDRGKQSLET ICLLLAFKIK YPENFFILRG 

       130        140        150        160        170        180 
NHECASINRI YGFYDECKRR YNIRLWKTFT DCFNCLPVAA IVDEKILCMH GGLSPELKTL 

       190        200        210        220        230        240 
EQIRRIPRPT DVPDTGLLCD LLWADPDKDV QGWGENDRGV SYTFGPDTVT EFLQRHDLDL 

       250        260        270        280        290        300 
VCRAHQVVED GYEFFAKRQL VTLFSAPNYC GEFDNAGALM SVDDTLMCSF QILKPSEKKG 

       310 
KFMQGGNSLA GAGRGTPRR 

« Hide

References

[1]"Protein phosphatase 2A, a potential regulator of actin dynamics and actin-based organelle motility in the green alga Acetabularia."
Menzel D., Vugrek O., Frank S., Elsner-Menzel C.
Eur. J. Cell Biol. 67:179-187(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z28627 Genomic DNA. Translation: CAA82263.1.

3D structure databases

ProteinModelPortalP48480.
SMRP48480. Positions 3-306.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP48480.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.60.21.10. 1 hit.
InterProIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSPR00114. STPHPHTASE.
SMARTSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMSSF56300. SSF56300. 1 hit.
PROSITEPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePP11_ACEPE
AccessionPrimary (citable) accession number: P48480
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: June 11, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families