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Protein

Putative serine/threonine-protein phosphatase C27B7.6

Gene

C27B7.6

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mn2+By similarityNote: Binds 2 manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi65Manganese 1By similarity1
Metal bindingi67Manganese 1By similarity1
Metal bindingi93Manganese 1By similarity1
Metal bindingi93Manganese 2By similarity1
Metal bindingi125Manganese 2By similarity1
Active sitei126Proton donorBy similarity1
Metal bindingi174Manganese 2By similarity1
Metal bindingi252Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandManganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative serine/threonine-protein phosphatase C27B7.6 (EC:3.1.3.16)
Gene namesi
ORF Names:C27B7.6
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiC27B7.6 ; CE43510 ; WBGene00007763

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000589161 – 454Putative serine/threonine-protein phosphatase C27B7.6Add BLAST454

Proteomic databases

PaxDbiP48460

Expressioni

Gene expression databases

BgeeiWBGene00007763

Interactioni

Protein-protein interaction databases

STRINGi6239.C27B7.6

Structurei

3D structure databases

ProteinModelPortaliP48460
SMRiP48460
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi425 – 448Pro-richAdd BLAST24

Sequence similaritiesi

Belongs to the PPP phosphatase family. PP-1 subfamily.Curated

Phylogenomic databases

eggNOGiKOG0374 Eukaryota
COG0639 LUCA
GeneTreeiENSGT00910000145027
InParanoidiP48460
OMAiANTEIHE
OrthoDBiEOG091G0CO1
PhylomeDBiP48460

Family and domain databases

Gene3Di3.60.21.10, 1 hit
InterProiView protein in InterPro
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
IPR006186 Ser/Thr-sp_prot-phosphatase
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PRINTSiPR00114 STPHPHTASE
SMARTiView protein in SMART
SM00156 PP2Ac, 1 hit
PROSITEiView protein in PROSITE
PS00125 SER_THR_PHOSPHATASE, 1 hit

Sequencei

Sequence statusi: Complete.

P48460-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLETEHANTE VHELCRQMIA RIEKYGTLEG FSDSDILEVL KTIKEILEPL
60 70 80 90 100
PCLIEIIAPV VVFGDIHGQL GDLLQFTNEV GRPPDFQYLF LGDYVDRGPN
110 120 130 140 150
SLEVTVWLFC MKILFSKKVH LLRGNHEVRR VNTMYGFKEE MMRKRNSHLW
160 170 180 190 200
KVFNDVFAEL SICASINRKI LCMHGGISPK IESWDSLTGM TKPRVHGDCE
210 220 230 240 250
HGLIVDLIWS DPNRKDDTIQ FNKMRGISTL FGKSVVDNLC TTLAIDLIIR
260 270 280 290 300
AHEMKEKGHT FEFDNRLLTV FSAPYYSGHN SNLGSVATIS KSLKLRIVTL
310 320 330 340 350
KPNKGYDRSK LDKRTLHDFE KNFQPLDENP RKNISCQFNV PPNGQKMSPF
360 370 380 390 400
LGEYSMFAHE TQFCKKDNET PVKKPYSSNQ DEDHSVLDMI RKTQKGYGVE
410 420 430 440 450
VSLKDKVMSL ESIRKKLGMT TSTTPPPPRT PSPDAPLAQS PPIPRSPPSS

TENA
Length:454
Mass (Da):51,597
Last modified:October 5, 2010 - v4
Checksum:i425C550C7B010E0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z54236 Genomic DNA Translation: CAA90981.4
PIRiT19505
RefSeqiNP_501547.3, NM_069146.4
UniGeneiCel.13464

Genome annotation databases

EnsemblMetazoaiC27B7.6; C27B7.6; WBGene00007763
GeneIDi182956
KEGGicel:CELE_C27B7.6
UCSCiC27B7.6 c. elegans

Similar proteinsi

Entry informationi

Entry nameiYY06_CAEEL
AccessioniPrimary (citable) accession number: P48460
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: October 5, 2010
Last modified: March 28, 2018
This is version 126 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health