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P48460

- YY06_CAEEL

UniProt

P48460 - YY06_CAEEL

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Protein

Putative serine/threonine-protein phosphatase C27B7.6

Gene
C27B7.6
Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi65 – 651Manganese 1 By similarity
Metal bindingi67 – 671Manganese 1 By similarity
Metal bindingi93 – 931Manganese 1 By similarity
Metal bindingi93 – 931Manganese 2 By similarity
Metal bindingi125 – 1251Manganese 2 By similarity
Active sitei126 – 1261Proton donor By similarity
Metal bindingi174 – 1741Manganese 2 By similarity
Metal bindingi252 – 2521Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative serine/threonine-protein phosphatase C27B7.6 (EC:3.1.3.16)
Gene namesi
ORF Names:C27B7.6
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome IV

Organism-specific databases

WormBaseiC27B7.6; CE43510; WBGene00007763.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 454454Putative serine/threonine-protein phosphatase C27B7.6PRO_0000058916Add
BLAST

Proteomic databases

PaxDbiP48460.

Interactioni

Protein-protein interaction databases

STRINGi6239.C27B7.6.

Structurei

3D structure databases

ProteinModelPortaliP48460.
SMRiP48460. Positions 20-339.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi425 – 44824Pro-richAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0639.
GeneTreeiENSGT00530000062911.
InParanoidiP48460.
OMAiTEHANTE.
OrthoDBiEOG7QRQZZ.
PhylomeDBiP48460.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P48460-1 [UniParc]FASTAAdd to Basket

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MLETEHANTE VHELCRQMIA RIEKYGTLEG FSDSDILEVL KTIKEILEPL    50
PCLIEIIAPV VVFGDIHGQL GDLLQFTNEV GRPPDFQYLF LGDYVDRGPN 100
SLEVTVWLFC MKILFSKKVH LLRGNHEVRR VNTMYGFKEE MMRKRNSHLW 150
KVFNDVFAEL SICASINRKI LCMHGGISPK IESWDSLTGM TKPRVHGDCE 200
HGLIVDLIWS DPNRKDDTIQ FNKMRGISTL FGKSVVDNLC TTLAIDLIIR 250
AHEMKEKGHT FEFDNRLLTV FSAPYYSGHN SNLGSVATIS KSLKLRIVTL 300
KPNKGYDRSK LDKRTLHDFE KNFQPLDENP RKNISCQFNV PPNGQKMSPF 350
LGEYSMFAHE TQFCKKDNET PVKKPYSSNQ DEDHSVLDMI RKTQKGYGVE 400
VSLKDKVMSL ESIRKKLGMT TSTTPPPPRT PSPDAPLAQS PPIPRSPPSS 450
TENA 454
Length:454
Mass (Da):51,597
Last modified:October 5, 2010 - v4
Checksum:i425C550C7B010E0B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z54236 Genomic DNA. Translation: CAA90981.4.
PIRiT19505.
RefSeqiNP_501547.3. NM_069146.4.
UniGeneiCel.13464.

Genome annotation databases

EnsemblMetazoaiC27B7.6; C27B7.6; WBGene00007763.
GeneIDi182956.
KEGGicel:CELE_C27B7.6.
UCSCiC27B7.6. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z54236 Genomic DNA. Translation: CAA90981.4 .
PIRi T19505.
RefSeqi NP_501547.3. NM_069146.4.
UniGenei Cel.13464.

3D structure databases

ProteinModelPortali P48460.
SMRi P48460. Positions 20-339.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6239.C27B7.6.

Proteomic databases

PaxDbi P48460.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai C27B7.6 ; C27B7.6 ; WBGene00007763 .
GeneIDi 182956.
KEGGi cel:CELE_C27B7.6.
UCSCi C27B7.6. c. elegans.

Organism-specific databases

CTDi 182956.
WormBasei C27B7.6 ; CE43510 ; WBGene00007763 .

Phylogenomic databases

eggNOGi COG0639.
GeneTreei ENSGT00530000062911.
InParanoidi P48460.
OMAi TEHANTE.
OrthoDBi EOG7QRQZZ.
PhylomeDBi P48460.

Miscellaneous databases

NextBioi 919424.

Family and domain databases

Gene3Di 3.60.21.10. 1 hit.
InterProi IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view ]
Pfami PF00149. Metallophos. 1 hit.
[Graphical view ]
PRINTSi PR00114. STPHPHTASE.
SMARTi SM00156. PP2Ac. 1 hit.
[Graphical view ]
SUPFAMi SSF56300. SSF56300. 1 hit.
PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiYY06_CAEEL
AccessioniPrimary (citable) accession number: P48460
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: October 5, 2010
Last modified: June 11, 2014
This is version 103 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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