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P48460 (YY06_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative serine/threonine-protein phosphatase C27B7.6
EC=3.1.3.16
Gene names
ORF Names:C27B7.6
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length454 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

A phosphoprotein + H2O = a protein + phosphate.

Cofactor

Binds 1 iron ion per subunit By similarity.

Binds 1 manganese ion per subunit By similarity.

Sequence similarities

Belongs to the PPP phosphatase family. PP-1 subfamily.

Ontologies

Keywords
   LigandIron
Manganese
Metal-binding
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 454454Putative serine/threonine-protein phosphatase C27B7.6
PRO_0000058916

Regions

Compositional bias425 – 44824Pro-rich

Sites

Active site1261Proton donor By similarity
Metal binding651Iron By similarity
Metal binding671Iron By similarity
Metal binding931Iron By similarity
Metal binding931Manganese By similarity
Metal binding1251Manganese By similarity
Metal binding1741Manganese By similarity
Metal binding2521Manganese By similarity

Sequences

Sequence LengthMass (Da)Tools
P48460 [UniParc].

Last modified October 5, 2010. Version 4.
Checksum: 425C550C7B010E0B

FASTA45451,597
        10         20         30         40         50         60 
MLETEHANTE VHELCRQMIA RIEKYGTLEG FSDSDILEVL KTIKEILEPL PCLIEIIAPV 

        70         80         90        100        110        120 
VVFGDIHGQL GDLLQFTNEV GRPPDFQYLF LGDYVDRGPN SLEVTVWLFC MKILFSKKVH 

       130        140        150        160        170        180 
LLRGNHEVRR VNTMYGFKEE MMRKRNSHLW KVFNDVFAEL SICASINRKI LCMHGGISPK 

       190        200        210        220        230        240 
IESWDSLTGM TKPRVHGDCE HGLIVDLIWS DPNRKDDTIQ FNKMRGISTL FGKSVVDNLC 

       250        260        270        280        290        300 
TTLAIDLIIR AHEMKEKGHT FEFDNRLLTV FSAPYYSGHN SNLGSVATIS KSLKLRIVTL 

       310        320        330        340        350        360 
KPNKGYDRSK LDKRTLHDFE KNFQPLDENP RKNISCQFNV PPNGQKMSPF LGEYSMFAHE 

       370        380        390        400        410        420 
TQFCKKDNET PVKKPYSSNQ DEDHSVLDMI RKTQKGYGVE VSLKDKVMSL ESIRKKLGMT 

       430        440        450 
TSTTPPPPRT PSPDAPLAQS PPIPRSPPSS TENA

« Hide

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		Z54236 Genomic DNA. Translation: CAA90981.4.
PIRT19505.
RefSeqNP_501547.3. NM_069146.4.

3D structure databases

ProteinModelPortalP48460.
SMRP48460. Positions 44-302.
ModBaseSearch...

Protein-protein interaction databases

STRING6239.C27B7.6.

Proteomic databases

PaxDbP48460.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaC27B7.6; C27B7.6; C27B7.6.
GeneID182956.
KEGGcel:CELE_C27B7.6.
UCSCC27B7.6. c. elegans.

Organism-specific databases

CTD182956.
WormBaseC27B7.6; CE43510; WBGene00007763.

Phylogenomic databases

eggNOGCOG0639.
GeneTreeENSGT00530000062911.
InParanoidP48460.
OMATEHANTE.

Family and domain databases

InterProIPR004843. Metallo_PEstase_dom.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSPR00114. STPHPHTASE.
SMARTSM00156. PP2Ac. 1 hit.
[Graphical view]
PROSITEPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio919424.

Entry information

Entry nameYY06_CAEEL
AccessionPrimary (citable) accession number: P48460
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: October 5, 2010
Last modified: May 1, 2013
This is version 93 of the entry and version 4 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase

SIMILARITY comments

Index of protein domains and families

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