P48459 (YSD1_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative serine/threonine-protein phosphatase C23G10.1
EC=3.1.3.16

Gene names

ORF Names:

C23G10.1

Organism

Caenorhabditis elegans [Reference proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	354 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 1 iron ion per subunit By similarity. Binds 1 manganese ion per subunit By similarity.
Sequence similarities	Belongs to the PPP phosphatase family. PP-1 subfamily.

Ontologies

Keywords
Ligand	Iron Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoprotein phosphatase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 354	354	Putative serine/threonine-protein phosphatase C23G10.1		PRO_0000058914
Sites
	Active site	157	1	Proton donor By similarity
	Metal binding	94	1	Iron By similarity
	Metal binding	96	1	Iron By similarity
	Metal binding	124	1	Iron By similarity
	Metal binding	124	1	Manganese By similarity
	Metal binding	156	1	Manganese By similarity
	Metal binding	208	1	Manganese By similarity
	Metal binding	282	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	P48459 [UniParc]. Last modified September 26, 2001. Version 2. Checksum: 7965CD59B8424EB2	FASTA	354	40,306
	10 20 30 40 50 60 MSKKPRVPEV AEMSAVSDND VIKEKGARDK MFQKQSDESN KMFAEHFIKT LLACKGMTKI 70 80 90 100 110 120 RTMDIFRLIH ICKKIFTVQK SMVEIDGPVR ICGDLHGQYP DLIRLFAQVL GGFPPDSNYL 130 140 150 160 170 180 FLGDYVDRGS FNLEVILLCL AYKARYPNNF MMLRGNHEVI HINEKYGFKD EVFNRKGEYH 190 200 210 220 230 240 DELYPEFNEM MDMMPLVALV GGRILCMHGG LSQHIKSLDD LRNLRRPFHS EDECLENDIM 250 260 270 280 290 300 WSDPAKVSGW TANPRGASVQ FGENEVKEMC KLLDIDLIVR GHQVVQDGYE FFAGKKLVTV 310 320 330 340 350 FSAPHYMQSF TNSAAVCKVS AGLEVSFEVL KPEDIRVEEI KCSAESSCAS DMQQ

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FO080630 Genomic DNA. Translation: CCD65292.1.
RefSeq	NP_498352.1. NM_065951.3.
3D structure databases
ProteinModelPortal	P48459.
SMR	P48459. Positions 41-332.
ModBase	Search...
Protein-protein interaction databases
STRING	6239.C23G10.1b.
Proteomic databases
PaxDb	P48459.
PRIDE	P48459.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	C23G10.1a; C23G10.1a; C23G10.1.
GeneID	175880.
KEGG	cel:CELE_C23G10.1.
UCSC	C23G10.1b. c. elegans.
Organism-specific databases
CTD	175880.
WormBase	C23G10.1a; CE27721; WBGene00016010.
Phylogenomic databases
eggNOG	COG0639.
GeneTree	ENSGT00530000062911.
HOGENOM	HOG000172697.
KO	K01090.
Gene expression databases
ArrayExpress	P48459.
Family and domain databases
InterPro	IPR004843. Metallo_PEstase_dom. IPR006186. Ser/Thr-sp_prot-phosphatase. [Graphical view]
Pfam	PF00149. Metallophos. 1 hit. [Graphical view]
PRINTS	PR00114. STPHPHTASE.
SMART	SM00156. PP2Ac. 1 hit. [Graphical view]
PROSITE	PS00125. SER_THR_PHOSPHATASE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	890126.

Entry information

Entry name

YSD1_CAEEL

Accession

Primary (citable) accession number: P48459

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	September 26, 2001
Last modified:	May 1, 2013
This is version 86 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Caenorhabditis annotation project