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P48459 (YSD1_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative serine/threonine-protein phosphatase C23G10.1

EC=3.1.3.16
Gene names
ORF Names:C23G10.1
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length354 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PPP phosphatase family. PP-1 subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 354354Putative serine/threonine-protein phosphatase C23G10.1
PRO_0000058914

Sites

Active site1571Proton donor By similarity
Metal binding941Manganese 1 By similarity
Metal binding961Manganese 1 By similarity
Metal binding1241Manganese 1 By similarity
Metal binding1241Manganese 2 By similarity
Metal binding1561Manganese 2 By similarity
Metal binding2081Manganese 2 By similarity
Metal binding2821Manganese 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
P48459 [UniParc].

Last modified September 26, 2001. Version 2.
Checksum: 7965CD59B8424EB2

FASTA35440,306
        10         20         30         40         50         60 
MSKKPRVPEV AEMSAVSDND VIKEKGARDK MFQKQSDESN KMFAEHFIKT LLACKGMTKI 

        70         80         90        100        110        120 
RTMDIFRLIH ICKKIFTVQK SMVEIDGPVR ICGDLHGQYP DLIRLFAQVL GGFPPDSNYL 

       130        140        150        160        170        180 
FLGDYVDRGS FNLEVILLCL AYKARYPNNF MMLRGNHEVI HINEKYGFKD EVFNRKGEYH 

       190        200        210        220        230        240 
DELYPEFNEM MDMMPLVALV GGRILCMHGG LSQHIKSLDD LRNLRRPFHS EDECLENDIM 

       250        260        270        280        290        300 
WSDPAKVSGW TANPRGASVQ FGENEVKEMC KLLDIDLIVR GHQVVQDGYE FFAGKKLVTV 

       310        320        330        340        350 
FSAPHYMQSF TNSAAVCKVS AGLEVSFEVL KPEDIRVEEI KCSAESSCAS DMQQ 

« Hide

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FO080630 Genomic DNA. Translation: CCD65292.1.
RefSeqNP_498352.1. NM_065951.3.
UniGeneCel.10819.

3D structure databases

ProteinModelPortalP48459.
SMRP48459. Positions 41-332.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING6239.C23G10.1b.

Proteomic databases

PaxDbP48459.
PRIDEP48459.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaC23G10.1a; C23G10.1a; WBGene00016010.
GeneID175880.
KEGGcel:CELE_C23G10.1.
UCSCC23G10.1b. c. elegans.

Organism-specific databases

CTD175880.
WormBaseC23G10.1a; CE27721; WBGene00016010.

Phylogenomic databases

eggNOGCOG0639.
GeneTreeENSGT00530000062911.
HOGENOMHOG000172697.
KOK01090.
OrthoDBEOG78D7Q1.

Family and domain databases

Gene3D3.60.21.10. 1 hit.
InterProIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSPR00114. STPHPHTASE.
SMARTSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMSSF56300. SSF56300. 1 hit.
PROSITEPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio890126.

Entry information

Entry nameYSD1_CAEEL
AccessionPrimary (citable) accession number: P48459
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: September 26, 2001
Last modified: June 11, 2014
This is version 94 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase