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Protein

Putative serine/threonine-protein phosphatase C23G10.1

Gene

C23G10.1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mn2+By similarityNote: Binds 2 manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi94Manganese 1By similarity1
Metal bindingi96Manganese 1By similarity1
Metal bindingi124Manganese 1By similarity1
Metal bindingi124Manganese 2By similarity1
Metal bindingi156Manganese 2By similarity1
Active sitei157Proton donorBy similarity1
Metal bindingi208Manganese 2By similarity1
Metal bindingi282Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandManganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative serine/threonine-protein phosphatase C23G10.1 (EC:3.1.3.16)
Gene namesi
ORF Names:C23G10.1
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiC23G10.1a ; CE27721 ; WBGene00016010

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000589141 – 354Putative serine/threonine-protein phosphatase C23G10.1Add BLAST354

Proteomic databases

PaxDbiP48459
PRIDEiP48459

Expressioni

Gene expression databases

BgeeiWBGene00016010
ExpressionAtlasiP48459 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi6239.C23G10.1b

Structurei

3D structure databases

ProteinModelPortaliP48459
SMRiP48459
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PPP phosphatase family. PP-1 subfamily.Curated

Phylogenomic databases

eggNOGiKOG0374 Eukaryota
COG0639 LUCA
GeneTreeiENSGT00530000062911
HOGENOMiHOG000172697
InParanoidiP48459
OrthoDBiEOG091G0EJY

Family and domain databases

Gene3Di3.60.21.10, 1 hit
InterProiView protein in InterPro
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
IPR006186 Ser/Thr-sp_prot-phosphatase
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PRINTSiPR00114 STPHPHTASE
SMARTiView protein in SMART
SM00156 PP2Ac, 1 hit
PROSITEiView protein in PROSITE
PS00125 SER_THR_PHOSPHATASE, 1 hit

Sequencei

Sequence statusi: Complete.

P48459-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKKPRVPEV AEMSAVSDND VIKEKGARDK MFQKQSDESN KMFAEHFIKT
60 70 80 90 100
LLACKGMTKI RTMDIFRLIH ICKKIFTVQK SMVEIDGPVR ICGDLHGQYP
110 120 130 140 150
DLIRLFAQVL GGFPPDSNYL FLGDYVDRGS FNLEVILLCL AYKARYPNNF
160 170 180 190 200
MMLRGNHEVI HINEKYGFKD EVFNRKGEYH DELYPEFNEM MDMMPLVALV
210 220 230 240 250
GGRILCMHGG LSQHIKSLDD LRNLRRPFHS EDECLENDIM WSDPAKVSGW
260 270 280 290 300
TANPRGASVQ FGENEVKEMC KLLDIDLIVR GHQVVQDGYE FFAGKKLVTV
310 320 330 340 350
FSAPHYMQSF TNSAAVCKVS AGLEVSFEVL KPEDIRVEEI KCSAESSCAS

DMQQ
Length:354
Mass (Da):40,306
Last modified:September 26, 2001 - v2
Checksum:i7965CD59B8424EB2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080630 Genomic DNA Translation: CCD65292.1
RefSeqiNP_498352.1, NM_065951.3
UniGeneiCel.10819

Genome annotation databases

EnsemblMetazoaiC23G10.1a; C23G10.1a; WBGene00016010
GeneIDi175880
UCSCiC23G10.1b c. elegans

Similar proteinsi

Entry informationi

Entry nameiYSD1_CAEEL
AccessioniPrimary (citable) accession number: P48459
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: September 26, 2001
Last modified: March 28, 2018
This is version 110 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health