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P48459

- YSD1_CAEEL

UniProt

P48459 - YSD1_CAEEL

Protein

Putative serine/threonine-protein phosphatase C23G10.1

Gene

C23G10.1

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 2 (26 Sep 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi94 – 941Manganese 1By similarity
    Metal bindingi96 – 961Manganese 1By similarity
    Metal bindingi124 – 1241Manganese 1By similarity
    Metal bindingi124 – 1241Manganese 2By similarity
    Metal bindingi156 – 1561Manganese 2By similarity
    Active sitei157 – 1571Proton donorBy similarity
    Metal bindingi208 – 2081Manganese 2By similarity
    Metal bindingi282 – 2821Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative serine/threonine-protein phosphatase C23G10.1 (EC:3.1.3.16)
    Gene namesi
    ORF Names:C23G10.1
    OrganismiCaenorhabditis elegans
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome III

    Organism-specific databases

    WormBaseiC23G10.1a; CE27721; WBGene00016010.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 354354Putative serine/threonine-protein phosphatase C23G10.1PRO_0000058914Add
    BLAST

    Proteomic databases

    PaxDbiP48459.
    PRIDEiP48459.

    Interactioni

    Protein-protein interaction databases

    STRINGi6239.C23G10.1b.

    Structurei

    3D structure databases

    ProteinModelPortaliP48459.
    SMRiP48459. Positions 41-332.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PPP phosphatase family. PP-1 subfamily.Curated

    Phylogenomic databases

    eggNOGiCOG0639.
    GeneTreeiENSGT00530000062911.
    HOGENOMiHOG000172697.
    KOiK01090.
    OrthoDBiEOG78D7Q1.

    Family and domain databases

    Gene3Di3.60.21.10. 1 hit.
    InterProiIPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view]
    PfamiPF00149. Metallophos. 1 hit.
    [Graphical view]
    PRINTSiPR00114. STPHPHTASE.
    SMARTiSM00156. PP2Ac. 1 hit.
    [Graphical view]
    SUPFAMiSSF56300. SSF56300. 1 hit.
    PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P48459-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSKKPRVPEV AEMSAVSDND VIKEKGARDK MFQKQSDESN KMFAEHFIKT    50
    LLACKGMTKI RTMDIFRLIH ICKKIFTVQK SMVEIDGPVR ICGDLHGQYP 100
    DLIRLFAQVL GGFPPDSNYL FLGDYVDRGS FNLEVILLCL AYKARYPNNF 150
    MMLRGNHEVI HINEKYGFKD EVFNRKGEYH DELYPEFNEM MDMMPLVALV 200
    GGRILCMHGG LSQHIKSLDD LRNLRRPFHS EDECLENDIM WSDPAKVSGW 250
    TANPRGASVQ FGENEVKEMC KLLDIDLIVR GHQVVQDGYE FFAGKKLVTV 300
    FSAPHYMQSF TNSAAVCKVS AGLEVSFEVL KPEDIRVEEI KCSAESSCAS 350
    DMQQ 354
    Length:354
    Mass (Da):40,306
    Last modified:September 26, 2001 - v2
    Checksum:i7965CD59B8424EB2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FO080630 Genomic DNA. Translation: CCD65292.1.
    RefSeqiNP_498352.1. NM_065951.3.
    UniGeneiCel.10819.

    Genome annotation databases

    EnsemblMetazoaiC23G10.1a; C23G10.1a; WBGene00016010.
    GeneIDi175880.
    KEGGicel:CELE_C23G10.1.
    UCSCiC23G10.1b. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FO080630 Genomic DNA. Translation: CCD65292.1 .
    RefSeqi NP_498352.1. NM_065951.3.
    UniGenei Cel.10819.

    3D structure databases

    ProteinModelPortali P48459.
    SMRi P48459. Positions 41-332.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 6239.C23G10.1b.

    Proteomic databases

    PaxDbi P48459.
    PRIDEi P48459.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai C23G10.1a ; C23G10.1a ; WBGene00016010 .
    GeneIDi 175880.
    KEGGi cel:CELE_C23G10.1.
    UCSCi C23G10.1b. c. elegans.

    Organism-specific databases

    CTDi 175880.
    WormBasei C23G10.1a ; CE27721 ; WBGene00016010 .

    Phylogenomic databases

    eggNOGi COG0639.
    GeneTreei ENSGT00530000062911.
    HOGENOMi HOG000172697.
    KOi K01090.
    OrthoDBi EOG78D7Q1.

    Miscellaneous databases

    NextBioi 890126.

    Family and domain databases

    Gene3Di 3.60.21.10. 1 hit.
    InterProi IPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view ]
    Pfami PF00149. Metallophos. 1 hit.
    [Graphical view ]
    PRINTSi PR00114. STPHPHTASE.
    SMARTi SM00156. PP2Ac. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56300. SSF56300. 1 hit.
    PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.

    Entry informationi

    Entry nameiYSD1_CAEEL
    AccessioniPrimary (citable) accession number: P48459
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: September 26, 2001
    Last modified: October 1, 2014
    This is version 95 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Caenorhabditis elegans
      Caenorhabditis elegans: entries, gene names and cross-references to WormBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3