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Protein

Putative serine/threonine-protein phosphatase C06A1.3

Gene

C06A1.3

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mn2+By similarityNote: Binds 2 manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi93Manganese 1By similarity1
Metal bindingi95Manganese 1By similarity1
Metal bindingi121Manganese 1By similarity1
Metal bindingi121Manganese 2By similarity1
Metal bindingi153Manganese 2By similarity1
Active sitei154Proton donorBy similarity1
Metal bindingi202Manganese 2By similarity1
Metal bindingi277Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandManganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative serine/threonine-protein phosphatase C06A1.3 (EC:3.1.3.16)
Gene namesi
ORF Names:C06A1.3
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiC06A1.3 ; CE02116 ; WBGene00007354

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000589151 – 364Putative serine/threonine-protein phosphatase C06A1.3Add BLAST364

Proteomic databases

EPDiP48458
PaxDbiP48458
PeptideAtlasiP48458
PRIDEiP48458

Expressioni

Gene expression databases

BgeeiWBGene00007354

Interactioni

Protein-protein interaction databases

BioGridi39942, 1 interactor
STRINGi6239.C06A1.3

Structurei

3D structure databases

ProteinModelPortaliP48458
SMRiP48458
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PPP phosphatase family. PP-1 subfamily.Curated

Phylogenomic databases

eggNOGiKOG0374 Eukaryota
COG0639 LUCA
GeneTreeiENSGT00530000062911
HOGENOMiHOG000172697
InParanoidiP48458
KOiK01090
OMAiVENIFME
OrthoDBiEOG091G0BA4
PhylomeDBiP48458

Family and domain databases

Gene3Di3.60.21.10, 1 hit
InterProiView protein in InterPro
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
IPR006186 Ser/Thr-sp_prot-phosphatase
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PRINTSiPR00114 STPHPHTASE
SMARTiView protein in SMART
SM00156 PP2Ac, 1 hit
PROSITEiView protein in PROSITE
PS00125 SER_THR_PHOSPHATASE, 1 hit

Sequencei

Sequence statusi: Complete.

P48458-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTDGNNNKK GSKEGPKSSE ISKFDLAKEN PKLAEWMDDC IKRMNSLYKD
60 70 80 90 100
TNINICNVMT GHEIISIIRM VEAIFMEESN LCEAEAPIKV IGDIHAQYQD
110 120 130 140 150
MNRLFDLIGR VPEEKLMFLG DYVDRGPQGI EVLILLFCLK IRYRDRIYLL
160 170 180 190 200
RGNHETPSVN KIYGFYVECQ YKYGIGLWWD FQSCFNRMPM SGLISKRVLC
210 220 230 240 250
MHGGLSPELI NLDTIRNIPR PCEPLDRGLL IDLLWSDPTN KGEGWFHSIR
260 270 280 290 300
GISYMFGKGV VEQACKSLEI DLIIRAHQVV QDGYEMMTGR RLITVFSVPN
310 320 330 340 350
YCAQFTNAAA VVCLNANLQI SFQQMIPPPL PEGTKAKAAP AIAIDPNIDA
360
ARADKDAIKP FVKE
Length:364
Mass (Da):41,208
Last modified:February 1, 1996 - v1
Checksum:i1384EAB0C9729913
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49886 Genomic DNA Translation: CAA90052.1
PIRiT18972
RefSeqiNP_496276.1, NM_063875.3
UniGeneiCel.15976

Genome annotation databases

EnsemblMetazoaiC06A1.3; C06A1.3; WBGene00007354
GeneIDi174626
KEGGicel:CELE_C06A1.3
UCSCiC06A1.3 c. elegans

Similar proteinsi

Entry informationi

Entry nameiYT91_CAEEL
AccessioniPrimary (citable) accession number: P48458
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: March 28, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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