P48429 (GST2_ASCSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutathione S-transferase 2
EC=2.5.1.18

Alternative name(s):
GST class-sigma

Gene names

Name:

GST2

Organism

Ascaris suum (Pig roundworm) (Ascaris lumbricoides)

Taxonomic identifier

6253 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Ascaridida › Ascaridoidea › Ascarididae › Ascaris

Protein attributes

Sequence length	20 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Catalytic activity	RX + glutathione = HX + R-S-glutathione.
Sequence similarities	Belongs to the GST superfamily. Sigma family. Contains 1 GST N-terminal domain.

Ontologies

Keywords
Molecular function	Transferase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Molecular function	glutathione transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›20	›20	Glutathione S-transferase 2		PRO_0000185924
Regions
	Domain	1 – ›20	›20	GST N-terminal
Experimental info
	Non-terminal residue	20	1

Sequences

	Sequence		Length	Mass (Da)
	P48429 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: A506D5F2B144FB20	FASTA	20	2,249
	10 20 GYKVTYFAIR GLAEPIXLLL

References

[1]	"Molecular cloning and expression of a cDNA encoding glutathione S-transferase from Ascaris suum." Liebau E., Schoenberger O.L., Walter R.D., Henkle-Duehrsen K.J. Mol. Biochem. Parasitol. 63:167-170(1994) [PubMed: 8183318] [Abstract] Cited for: PROTEIN SEQUENCE.

Cross-references

3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR012336. Thioredoxin-like_fold. [Graphical view]
Gene3D	G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
PROSITE	PS50404. GST_NTER. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GST2_ASCSU

Accession

Primary (citable) accession number: P48429

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	July 27, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)