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Protein

Chalcone synthase B

Gene

CHSB

Organism
Ipomoea purpurea (Common morning glory) (Pharbitis purpurea)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

Pathwayi: flavonoid biosynthesis

This protein is involved in the pathway flavonoid biosynthesis, which is part of Secondary metabolite biosynthesis.
View all proteins of this organism that are known to be involved in the pathway flavonoid biosynthesis and in Secondary metabolite biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei170PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase
Biological processFlavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase B (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase B
Short name:
CHS-B
Gene namesi
Name:CHSB
OrganismiIpomoea purpurea (Common morning glory) (Pharbitis purpurea)
Taxonomic identifieri4121 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesConvolvulaceaeIpomoeeaeIpomoea

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002159931 – 396Chalcone synthase BAdd BLAST396

Proteomic databases

PRIDEiP48398

Structurei

3D structure databases

ProteinModelPortaliP48398
SMRiP48398
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chalcone/stilbene synthases family.Curated

Family and domain databases

Gene3Di3.40.47.10, 2 hits
InterProiView protein in InterPro
IPR012328 Chalcone/stilbene_synth_C
IPR018088 Chalcone/stilbene_synthase_AS
IPR001099 Chalcone/stilbene_synthase_N
IPR011141 Polyketide_synthase_type-III
IPR016039 Thiolase-like
PANTHERiPTHR11877 PTHR11877, 1 hit
PfamiView protein in Pfam
PF02797 Chal_sti_synt_C, 1 hit
PF00195 Chal_sti_synt_N, 1 hit
PIRSFiPIRSF000451 PKS_III, 1 hit
SUPFAMiSSF53901 SSF53901, 2 hits
PROSITEiView protein in PROSITE
PS00441 CHALCONE_SYNTH, 1 hit

Sequencei

Sequence statusi: Complete.

P48398-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTTVTVLTD TWSRRAKRLE GDAKILAIGT ATPASWVDQT TYPDFYFRIT
60 70 80 90 100
NSQHLLEHKE KFRRICNKSK IRKRHLVLTE ELLKKNPNLC TYNETSLNTR
110 120 130 140 150
QDILVSEVPK LGKEAAMKAI KEWGRPISEI THLVFCTTSG VDMPGADFQL
160 170 180 190 200
TKLLGLNSSV KRLMMYQQGC NAGAAMLRLA KDLAESNKGG RVLVVCAEIT
210 220 230 240 250
INIFRGPSLE QDDNLLAQCL FGDGAAAMIV AADPRPGLET PLFELVSSAQ
260 270 280 290 300
TIVPNTDSHL KLHLREMGLT FHCSKAVPSV LAENVEDCLV KAFEPYGISD
310 320 330 340 350
WNSIFWVFHP GGNAIVDRVE ERLGLGPEKL RASRDVLSEY GNLTSACVLF
360 370 380 390
ILDEMRKKSK KDEQMTTGEG LEWGVVFGFG PGLTIDTIII RSVPIN
Length:396
Mass (Da):43,927
Last modified:February 1, 1996 - v1
Checksum:i352C478C1AF892B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U15947 Genomic DNA Translation: AAC49030.1
PIRiT10951

Similar proteinsi

Entry informationi

Entry nameiCHSB_IPOPU
AccessioniPrimary (citable) accession number: P48398
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: May 23, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

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