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P48392

- CHS3_GERHY

UniProt

P48392 - CHS3_GERHY

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Protein

Chalcone synthase 3

Gene

CHS3

Organism
Gerbera hybrida (Daisy)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei170 – 1701PROSITE-ProRule annotation

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase 3 (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase 3
Gene namesi
Name:CHS3
OrganismiGerbera hybrida (Daisy)
Taxonomic identifieri18101 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridscampanulidsAsteralesAsteraceaeMutisioideaeMutisieaeGerbera

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 403403Chalcone synthase 3PRO_0000215978Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP48392.
SMRiP48392. Positions 10-393.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chalcone/stilbene synthases family.Curated

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P48392-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MATSPAVIDV ETIRKAQRAE GPATILAIGT ATPANCVYQA DYPDYYFRVT
60 70 80 90 100
ESEHMVDLKE KFQRMCDKSM IRKRYMHITE EFLKENPSMC KFMAPSLDAR
110 120 130 140 150
QDLVVVEVPK LGKEAATKAI KEWGFPKSKI THLVFCTTSG VDMPGADYQL
160 170 180 190 200
TKLLGLRPSV KRLMMYQQGC FAGGTVLRLA KDLAENNKGA RVLVVCSEIT
210 220 230 240 250
AVTFRGPNEG HLDSLVGQAL FGDGAAAVII GSDPDLSVER PLFEMVSAAQ
260 270 280 290 300
TILPDSEGAI DGHLKEVGLT FHLLKDVPAL IAKNIEKALI QAFSPLNIND
310 320 330 340 350
WNSIFWIAHP GGPAILDQVE FKLGLREEKL RASRHVLSEY GNMSSACVLF
360 370 380 390 400
ILDEMRKKSI KDGKTTTGEG LEWGVLFGFG PGLTVETVVL HSLPATISVA

TQN
Length:403
Mass (Da):44,129
Last modified:February 1, 1996 - v1
Checksum:i819E10C6E4255140
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z38098 mRNA. Translation: CAA86220.1.
PIRiS56701. S55464.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z38098 mRNA. Translation: CAA86220.1 .
PIRi S56701. S55464.

3D structure databases

ProteinModelPortali P48392.
SMRi P48392. Positions 10-393.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00154 .

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Chalcone synthase-like genes active during corolla development are differentially expressed and encode enzymes with different catalytic properties in Gerbera hybrida (Asteraceae)."
    Helariutta Y., Elomaa P., Kotilainen M., Griesbach R.J., Schroeder J., Teeri T.H.
    Plant Mol. Biol. 28:47-60(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Corolla.

Entry informationi

Entry nameiCHS3_GERHY
AccessioniPrimary (citable) accession number: P48392
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: October 1, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3