Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P48392

- CHS3_GERHY

UniProt

P48392 - CHS3_GERHY

Protein

Chalcone synthase 3

Gene

CHS3

Organism
Gerbera hybrida (Daisy)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

    Catalytic activityi

    3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei170 – 1701PROSITE-ProRule annotation

    GO - Molecular functioni

    1. naringenin-chalcone synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. flavonoid biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Keywords - Biological processi

    Flavonoid biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00154.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chalcone synthase 3 (EC:2.3.1.74)
    Alternative name(s):
    Naringenin-chalcone synthase 3
    Gene namesi
    Name:CHS3
    OrganismiGerbera hybrida (Daisy)
    Taxonomic identifieri18101 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridscampanulidsAsteralesAsteraceaeMutisioideaeMutisieaeGerbera

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 403403Chalcone synthase 3PRO_0000215978Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP48392.
    SMRiP48392. Positions 10-393.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the chalcone/stilbene synthases family.Curated

    Family and domain databases

    Gene3Di3.40.47.10. 2 hits.
    InterProiIPR012328. Chalcone/stilbene_synth_C.
    IPR018088. Chalcone/stilbene_synthase_AS.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011141. Polyketide_synthase_type-III.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view]
    PfamiPF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000451. PKS_III. 1 hit.
    SUPFAMiSSF53901. SSF53901. 2 hits.
    PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P48392-1 [UniParc]FASTAAdd to Basket

    « Hide

    MATSPAVIDV ETIRKAQRAE GPATILAIGT ATPANCVYQA DYPDYYFRVT    50
    ESEHMVDLKE KFQRMCDKSM IRKRYMHITE EFLKENPSMC KFMAPSLDAR 100
    QDLVVVEVPK LGKEAATKAI KEWGFPKSKI THLVFCTTSG VDMPGADYQL 150
    TKLLGLRPSV KRLMMYQQGC FAGGTVLRLA KDLAENNKGA RVLVVCSEIT 200
    AVTFRGPNEG HLDSLVGQAL FGDGAAAVII GSDPDLSVER PLFEMVSAAQ 250
    TILPDSEGAI DGHLKEVGLT FHLLKDVPAL IAKNIEKALI QAFSPLNIND 300
    WNSIFWIAHP GGPAILDQVE FKLGLREEKL RASRHVLSEY GNMSSACVLF 350
    ILDEMRKKSI KDGKTTTGEG LEWGVLFGFG PGLTVETVVL HSLPATISVA 400
    TQN 403
    Length:403
    Mass (Da):44,129
    Last modified:February 1, 1996 - v1
    Checksum:i819E10C6E4255140
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z38098 mRNA. Translation: CAA86220.1.
    PIRiS56701. S55464.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z38098 mRNA. Translation: CAA86220.1 .
    PIRi S56701. S55464.

    3D structure databases

    ProteinModelPortali P48392.
    SMRi P48392. Positions 10-393.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00154 .

    Family and domain databases

    Gene3Di 3.40.47.10. 2 hits.
    InterProi IPR012328. Chalcone/stilbene_synth_C.
    IPR018088. Chalcone/stilbene_synthase_AS.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011141. Polyketide_synthase_type-III.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view ]
    Pfami PF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000451. PKS_III. 1 hit.
    SUPFAMi SSF53901. SSF53901. 2 hits.
    PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Chalcone synthase-like genes active during corolla development are differentially expressed and encode enzymes with different catalytic properties in Gerbera hybrida (Asteraceae)."
      Helariutta Y., Elomaa P., Kotilainen M., Griesbach R.J., Schroeder J., Teeri T.H.
      Plant Mol. Biol. 28:47-60(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Corolla.

    Entry informationi

    Entry nameiCHS3_GERHY
    AccessioniPrimary (citable) accession number: P48392
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3