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Protein

14-3-3-like protein GF14 epsilon

Gene

GRF10

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes.

GO - Molecular functioni

  • ATP binding Source: TAIR

GO - Biological processi

  • brassinosteroid mediated signaling pathway Source: TAIR
  • response to abscisic acid Source: TAIR
Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-ATH-3371453. Regulation of HSF1-mediated heat shock response.
R-ATH-3371511. HSF1 activation.

Names & Taxonomyi

Protein namesi
Recommended name:
14-3-3-like protein GF14 epsilon
Alternative name(s):
General regulatory factor 10
Gene namesi
Name:GRF10
Ordered Locus Names:At1g22300
ORF Names:T16E15.8
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G22300.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: TAIR
  • mitochondrion Source: TAIR
  • plasma membrane Source: TAIR
  • plasmodesma Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000586721 – 25414-3-3-like protein GF14 epsilonAdd BLAST254

Proteomic databases

PaxDbiP48347.
PRIDEiP48347.

PTM databases

iPTMnetiP48347.

Expressioni

Gene expression databases

ExpressionAtlasiP48347. baseline and differential.
GenevisibleiP48347. AT.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
TOC34Q410092EBI-1803304,EBI-638506From a different organism.

Protein-protein interaction databases

BioGridi24076. 80 interactors.
IntActiP48347. 4 interactors.
MINTiMINT-2584273.
STRINGi3702.AT1G22300.1.

Structurei

3D structure databases

ProteinModelPortaliP48347.
SMRiP48347.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 14-3-3 family.Curated

Phylogenomic databases

eggNOGiKOG0841. Eukaryota.
COG5040. LUCA.
HOGENOMiHOG000240379.
InParanoidiP48347.
KOiK06630.
OMAiESKGHEQ.
PhylomeDBiP48347.

Family and domain databases

InterProiIPR000308. 14-3-3.
IPR023409. 14-3-3_CS.
IPR023410. 14-3-3_domain.
[Graphical view]
PANTHERiPTHR18860. PTHR18860. 1 hit.
PfamiPF00244. 14-3-3. 1 hit.
[Graphical view]
PIRSFiPIRSF000868. 14-3-3. 1 hit.
PRINTSiPR00305. 1433ZETA.
SMARTiSM00101. 14_3_3. 1 hit.
[Graphical view]
SUPFAMiSSF48445. SSF48445. 1 hit.
PROSITEiPS00796. 1433_1. 1 hit.
PS00797. 1433_2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: P48347-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MENEREKQVY LAKLSEQTER YDEMVEAMKK VAQLDVELTV EERNLVSVGY
60 70 80 90 100
KNVIGARRAS WRILSSIEQK EESKGNDENV KRLKNYRKRV EDELAKVCND
110 120 130 140 150
ILSVIDKHLI PSSNAVESTV FFYKMKGDYY RYLAEFSSGA ERKEAADQSL
160 170 180 190 200
EAYKAAVAAA ENGLAPTHPV RLGLALNFSV FYYEILNSPE SACQLAKQAF
210 220 230 240 250
DDAIAELDSL NEESYKDSTL IMQLLRDNLT LWTSDLNEEG DERTKGADEP

QDEN
Length:254
Mass (Da):28,915
Last modified:February 1, 1996 - v1
Checksum:i037405C341845C25
GO
Isoform 2 (identifier: P48347-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     254-254: N → V

Show »
Length:254
Mass (Da):28,900
Checksum:i15F405C341845C25
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_008972254N → V in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U36446 mRNA. Translation: AAA79699.1.
AF145302 Genomic DNA. Translation: AAD51785.1.
AC068562 Genomic DNA. Translation: AAF87261.1.
CP002684 Genomic DNA. Translation: AEE30225.1.
CP002684 Genomic DNA. Translation: AEE30226.1.
AF334382 mRNA. Translation: AAG50088.1.
AY054505 mRNA. Translation: AAK96696.1.
AY058834 mRNA. Translation: AAL24222.1.
AY062838 mRNA. Translation: AAL32916.1.
AY081674 mRNA. Translation: AAM10236.1.
AY087580 mRNA. Translation: AAM65122.1.
PIRiH86355.
RefSeqiNP_564167.1. NM_102081.4. [P48347-1]
NP_849698.1. NM_179367.2. [P48347-2]
UniGeneiAt.24553.
At.67728.

Genome annotation databases

EnsemblPlantsiAT1G22300.1; AT1G22300.1; AT1G22300. [P48347-1]
GeneIDi838837.
GrameneiAT1G22300.1; AT1G22300.1; AT1G22300.
KEGGiath:AT1G22300.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U36446 mRNA. Translation: AAA79699.1.
AF145302 Genomic DNA. Translation: AAD51785.1.
AC068562 Genomic DNA. Translation: AAF87261.1.
CP002684 Genomic DNA. Translation: AEE30225.1.
CP002684 Genomic DNA. Translation: AEE30226.1.
AF334382 mRNA. Translation: AAG50088.1.
AY054505 mRNA. Translation: AAK96696.1.
AY058834 mRNA. Translation: AAL24222.1.
AY062838 mRNA. Translation: AAL32916.1.
AY081674 mRNA. Translation: AAM10236.1.
AY087580 mRNA. Translation: AAM65122.1.
PIRiH86355.
RefSeqiNP_564167.1. NM_102081.4. [P48347-1]
NP_849698.1. NM_179367.2. [P48347-2]
UniGeneiAt.24553.
At.67728.

3D structure databases

ProteinModelPortaliP48347.
SMRiP48347.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi24076. 80 interactors.
IntActiP48347. 4 interactors.
MINTiMINT-2584273.
STRINGi3702.AT1G22300.1.

PTM databases

iPTMnetiP48347.

Proteomic databases

PaxDbiP48347.
PRIDEiP48347.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G22300.1; AT1G22300.1; AT1G22300. [P48347-1]
GeneIDi838837.
GrameneiAT1G22300.1; AT1G22300.1; AT1G22300.
KEGGiath:AT1G22300.

Organism-specific databases

TAIRiAT1G22300.

Phylogenomic databases

eggNOGiKOG0841. Eukaryota.
COG5040. LUCA.
HOGENOMiHOG000240379.
InParanoidiP48347.
KOiK06630.
OMAiESKGHEQ.
PhylomeDBiP48347.

Enzyme and pathway databases

ReactomeiR-ATH-3371453. Regulation of HSF1-mediated heat shock response.
R-ATH-3371511. HSF1 activation.

Miscellaneous databases

PROiP48347.

Gene expression databases

ExpressionAtlasiP48347. baseline and differential.
GenevisibleiP48347. AT.

Family and domain databases

InterProiIPR000308. 14-3-3.
IPR023409. 14-3-3_CS.
IPR023410. 14-3-3_domain.
[Graphical view]
PANTHERiPTHR18860. PTHR18860. 1 hit.
PfamiPF00244. 14-3-3. 1 hit.
[Graphical view]
PIRSFiPIRSF000868. 14-3-3. 1 hit.
PRINTSiPR00305. 1433ZETA.
SMARTiSM00101. 14_3_3. 1 hit.
[Graphical view]
SUPFAMiSSF48445. SSF48445. 1 hit.
PROSITEiPS00796. 1433_1. 1 hit.
PS00797. 1433_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry namei14310_ARATH
AccessioniPrimary (citable) accession number: P48347
Secondary accession number(s): Q9LME5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: November 30, 2016
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.