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Protein

Protein RecA

Gene

recA

Organism
Thermus aquaticus
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi65 – 72ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA damage, DNA recombination, DNA repair, SOS response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RecAUniRule annotation
Alternative name(s):
Recombinase AUniRule annotation
Gene namesi
Name:recAUniRule annotation
OrganismiThermus aquaticus
Taxonomic identifieri271 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001228791 – 340Protein RecAAdd BLAST340

Interactioni

Protein-protein interaction databases

DIPiDIP-61165N.

Structurei

3D structure databases

ProteinModelPortaliP48296.
SMRiP48296.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C68. Bacteria.
COG0468. LUCA.

Family and domain databases

CDDicd00983. recA. 1 hit.
Gene3Di3.30.250.10. 1 hit.
HAMAPiMF_00268. RecA. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR023400. RecA_C.
IPR020587. RecA_monomer-monomer_interface.
PANTHERiPTHR22942:SF1. PTHR22942:SF1. 1 hit.
PfamiView protein in Pfam
PF00154. RecA. 1 hit.
PRINTSiPR00142. RECA.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF54752. SSF54752. 1 hit.
TIGRFAMsiTIGR02012. tigrfam_recA. 1 hit.
PROSITEiView protein in PROSITE
PS00321. RECA_1. 1 hit.
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.

Sequencei

Sequence statusi: Complete.

P48296-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEENKRKSLE NALKTIEKEF GKGAVMRLGE MPKLQVDVIP TGSLGLDLAL
60 70 80 90 100
GIGGIPRGRV TEIFGPESGG KTTLALTIIA QAQKGGGVAA FVDAEHALDP
110 120 130 140 150
LYAKKLGVDV QELLVSQPDT GEQALEIVEL LARSGAVDVI VVDSVAALVP
160 170 180 190 200
KAEIEGEMGD QHVGLQARLM SQALRKLTAV LSKSNTAAIF INQVREKVGV
210 220 230 240 250
MYGNPETTPG GRALKFYSSV RLDVRKSGQP IKVGNEAVGI KVKVKVVKNK
260 270 280 290 300
LAPPFREAEL EIYFGRGLDP VMDLVNVAVA AGVIEKAGSW FSYGEHRLGQ
310 320 330 340
GKEKAAEYLR ERPELLEEIR AKVLERADKV VLAAGEEEGE
Length:340
Mass (Da):36,454
Last modified:February 1, 1996 - v1
Checksum:i0411D8437623A7AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L20680 Unassigned DNA. Translation: AAA19796.1.
L20095 Genomic DNA. Translation: AAA27502.1.
PIRiA53378.

Similar proteinsi

Entry informationi

Entry nameiRECA_THEAQ
AccessioniPrimary (citable) accession number: P48296
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: October 25, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families