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Protein

Glutamate transport system permease protein GluC

Gene

gluC

Organism
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the binding-protein-dependent transport system for glutamate; probably responsible for the translocation of the substrate across the membrane.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Protein family/group databases

TCDBi3.A.1.3.9. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate transport system permease protein GluC
Gene namesi
Name:gluC
Ordered Locus Names:Cgl1952, cg2138
OrganismiCorynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Taxonomic identifieri196627 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
Proteomesi
  • UP000000582 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei16 – 3621HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei64 – 8421HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei100 – 12021HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei134 – 15623HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei161 – 18323HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei195 – 21521HelicalPROSITE-ProRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 228228Glutamate transport system permease protein GluCPRO_0000060041Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi196627.cg2138.

Structurei

3D structure databases

ProteinModelPortaliP48244.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini16 – 217202ABC transmembrane type-1PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108Q1T. Bacteria.
COG0765. LUCA.
HOGENOMiHOG000267552.
KOiK10006.
OMAiMMSEMIE.
OrthoDBiEOG6MM1R5.

Family and domain databases

Gene3Di1.10.3720.10. 1 hit.
InterProiIPR010065. AA_ABC_transptr_permease_3TM.
IPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
TIGRFAMsiTIGR01726. HEQRo_perm_3TM. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P48244-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTLWADLGP SLLPAFWVTI KLTIYSAIGA MIFGTILTTM RVSPVKILRT
60 70 80 90 100
LSTAYINTVR NTPLTLVVLF CSFGLYQNLG LTLAGRESST FLVDNNFRLA
110 120 130 140 150
VLGFILYTST FVAESLRSGI NTVHFGQAEA ARSLGLGFGA TFRSIIFPQA
160 170 180 190 200
VRAAIVPLGN TLIALTKNTT IASVIGVGEA SLLMKATIEN HANMLFVVFA
210 220
IFAVGFMILT LPMGLGLGKL SERLAVKK
Length:228
Mass (Da):24,469
Last modified:July 26, 2002 - v2
Checksum:iCD33B2A31AB37C17
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti211 – 22818LPMGL…LAVKK → CLWALAWANSLSVWR in CAA57062 (PubMed:7868586).CuratedAdd
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X81191 Genomic DNA. Translation: CAA57062.1.
BA000036 Genomic DNA. Translation: BAB99345.1.
BX927153 Genomic DNA. Translation: CAF20293.1.
RefSeqiNP_601159.1. NC_003450.3.
WP_011014780.1. NC_006958.1.

Genome annotation databases

EnsemblBacteriaiBAB99345; BAB99345; BAB99345.
CAF20293; CAF20293; cg2138.
GeneIDi1019909.
KEGGicgb:cg2138.
cgl:NCgl1877.
PATRICi21495908. VBICorGlu203724_1890.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X81191 Genomic DNA. Translation: CAA57062.1.
BA000036 Genomic DNA. Translation: BAB99345.1.
BX927153 Genomic DNA. Translation: CAF20293.1.
RefSeqiNP_601159.1. NC_003450.3.
WP_011014780.1. NC_006958.1.

3D structure databases

ProteinModelPortaliP48244.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi196627.cg2138.

Protein family/group databases

TCDBi3.A.1.3.9. the atp-binding cassette (abc) superfamily.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB99345; BAB99345; BAB99345.
CAF20293; CAF20293; cg2138.
GeneIDi1019909.
KEGGicgb:cg2138.
cgl:NCgl1877.
PATRICi21495908. VBICorGlu203724_1890.

Phylogenomic databases

eggNOGiENOG4108Q1T. Bacteria.
COG0765. LUCA.
HOGENOMiHOG000267552.
KOiK10006.
OMAiMMSEMIE.
OrthoDBiEOG6MM1R5.

Family and domain databases

Gene3Di1.10.3720.10. 1 hit.
InterProiIPR010065. AA_ABC_transptr_permease_3TM.
IPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
TIGRFAMsiTIGR01726. HEQRo_perm_3TM. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Structure of the gluABCD cluster encoding the glutamate uptake system of Corynebacterium glutamicum."
    Kronemeyer W., Peekhaus N., Kraemer R., Sahm H., Eggeling L.
    J. Bacteriol. 177:1152-1158(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
  2. "The Corynebacterium glutamicum genome: features and impacts on biotechnological processes."
    Ikeda M., Nakagawa S.
    Appl. Microbiol. Biotechnol. 62:99-109(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

Entry informationi

Entry nameiGLUC_CORGL
AccessioniPrimary (citable) accession number: P48244
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: July 26, 2002
Last modified: December 9, 2015
This is version 104 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.