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Protein

60 kDa chaperonin

Gene

groL

Organism
Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation, mopA
Ordered Locus Names:ZMO1929
OrganismiZymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
Taxonomic identifieri264203 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeZymomonas
Proteomesi
  • UP000001173 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000636171 – 54660 kDa chaperoninAdd BLAST546

Proteomic databases

PRIDEiP48220.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliP48220.
SMRiP48220.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076290.
KOiK04077.
OMAiWTSPKIT.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR037290. Cpn60/TCP-1_sf.
IPR027409. GroEL-like_apical_dom_sf.
IPR027413. GROEL-like_equatorial_sf.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

P48220-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKDVKFSR DARERILRGV DILADAVKVT LGPKGRNVVL DKAFGAPRIT
60 70 80 90 100
KDGVSVAKEI ELKDKFENMG AQMLREVASK TNDLAGDGTT TATVLAQAIV
110 120 130 140 150
REGMKSVAAG MNPMDLKRGI DLAATKVVES LRSRSKPVSD FNEVAQVGII
160 170 180 190 200
SANGDEEVGR RIAEAMEKVG KEGVITVEEA KGFDFELDVV EGMQFDRGYL
210 220 230 240 250
SPYFITNPEK MVAELADPYI LIYEKKLSNL QSILPILESV VQSGRPLLII
260 270 280 290 300
AEDIEGEALA TLVVNKLRGG LKVAAVKAPG FGDRRKAMLE DIAILTKGEL
310 320 330 340 350
ISEDLGIKLE NVTLNMLGSA KRVSITKENT TIVDGAGDQS TIKDRVEAIR
360 370 380 390 400
SQIEATTSDY DREKLQERVA KLAGGVAVIK VGGATEVEVK ERKDRVDDAL
410 420 430 440 450
HATRAAVQEG IVPGGGTALL YATKTLEGLN GVNEDQQRGI DIVRRALQAP
460 470 480 490 500
VRQIAQNAGF DGAVVAGKLI DGNDDKIGFN AQTEKYEDLA ATGVIDPTKV
510 520 530 540
VRTALQDAAS VAGLLITTEA AVGDLPEDKP APAMPGGMGG MGGMDF
Length:546
Mass (Da):58,122
Last modified:February 15, 2005 - v2
Checksum:iD7492F8AA2DED631
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti36 – 73RNVVL…MGAQM → VTLFWTKPLVLPYHQRWCFC RQRNRTERQVRKYGHRC (PubMed:7926837).CuratedAdd BLAST38
Sequence conflicti78A → P in AAA62399 (PubMed:7926837).Curated1
Sequence conflicti425T → A in AAA62399 (PubMed:7926837).Curated1
Sequence conflicti545 – 546DF → GGMDF (PubMed:7926837).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L11654 Genomic DNA. Translation: AAA62399.1.
AE008692 Genomic DNA. Translation: AAV90553.1.
PIRiJC2564.
RefSeqiWP_011241653.1. NC_006526.2.

Genome annotation databases

EnsemblBacteriaiAAV90553; AAV90553; ZMO1929.
KEGGizmo:ZMO1929.

Similar proteinsi

Entry informationi

Entry nameiCH60_ZYMMO
AccessioniPrimary (citable) accession number: P48220
Secondary accession number(s): Q5NL57
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 15, 2005
Last modified: November 22, 2017
This is version 108 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families