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Protein

60 kDa chaperonin

Gene

groL

Organism
Neisseria flavescens
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
63 kDa stress protein
GSP63
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation, hsp63, mopA
OrganismiNeisseria flavescens
Taxonomic identifieri484 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000634561 – 54460 kDa chaperoninAdd BLAST544

Proteomic databases

PRIDEiP48215.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliP48215.
SMRiP48215.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR037290. Cpn60/TCP-1_sf.
IPR027409. GroEL-like_apical_dom_sf.
IPR027413. GROEL-like_equatorial_sf.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

P48215-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKDVQFGN EVRQKMVNGV NILANAVRVT LGPKGRNVVL DRAFGGPHIT
60 70 80 90 100
KDGVSVAKEI ELKDKFENMG AQMVKEVASK TNDVAGDGTT TATVLAQSIV
110 120 130 140 150
AEGMKYVTAG MNPTDLKRGI DKAVAALVDE LKNIAKPCDT SKEIAQVGSI
160 170 180 190 200
SANSDEQVGA IIAEAMEKVG KEGVITVEDG KSLENELDVV EGMQFDRGYL
210 220 230 240 250
SPYFINDAEK QIAGLDNPFV LLFDKKISNI RDLLPVLEQV AKASRPLLII
260 270 280 290 300
AEDVEGEALA TLVVNNIRGI LKTVAVKAPG FGDRRKAMLQ DIAILTGGVV
310 320 330 340 350
ISEEVGLSLE KATLDDLGQA KRIEIGKENT TIIDGFGDAA QIEARVAEIR
360 370 380 390 400
QQIETATSDY GKEKLQERVA KLAGGVAVIK VGAATEVEMK EKKDRVEDAL
410 420 430 440 450
HATRAAVEEG VVAGGGVALL RARAALENLH TGNADQEAGV QIVLRAVESP
460 470 480 490 500
LRQIVAKAGG EPSVVVNKVL EGKGNYGYKA GSGEYGDMIE MGVLDPAKVT
510 520 530 540
RSALQHAASI AGLMLTTDCM IAEIPERKPA MPDMGGMGGM GGMM
Length:544
Mass (Da):57,466
Last modified:February 1, 1996 - v1
Checksum:iC4E70667C2AB035B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z22955 Genomic DNA. Translation: CAA80531.1.
PIRiS61302.

Similar proteinsi

Entry informationi

Entry nameiCH60_NEIFL
AccessioniPrimary (citable) accession number: P48215
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: November 22, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families