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Protein

60 kDa chaperonin

Gene

groL

Organism
Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:cpn60, groELUniRule annotation, mopA
Ordered Locus Names:BP3495
OrganismiBordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Taxonomic identifieri257313 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
Proteomesi
  • UP000002676 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000632931 – 54760 kDa chaperoninAdd BLAST547

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi257313.BP3495.

Structurei

3D structure databases

ProteinModelPortaliP48210.
SMRiP48210.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR037290. Cpn60/TCP-1_sf.
IPR027409. GroEL-like_apical_dom_sf.
IPR027413. GROEL-like_equatorial_sf.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

P48210-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKQVLFAD EARVRIVRGV NVLANAVKTT LGPKGRNVVL ERSFGAPTVT
60 70 80 90 100
KDGVSVAKEI ELKDKFENIG AQLVKDVASK TSDNAGDGTT TATVLAQAVV
110 120 130 140 150
QEGLKYVAAG FNPIDLKRGI DKAVAAAVEE LKKLSKPVTT SKEIAQVGSI
160 170 180 190 200
SANSDASIGQ IIADAMDKVG KEGVITVEDG KSLENELDVV EGMQFDRGYL
210 220 230 240 250
SPYFINSPEK QVAALDDPYV LIYDKKVSNI RDLLPVLEQV AKSSRPLLII
260 270 280 290 300
AEDVEGEALA TLVVNNIRGI LKTTAVKAPG FGDRRKAMLE DIAILTGGTV
310 320 330 340 350
ISEETGMSLE KATLQDLGQA KRIEVAKENT TIIDGAGDGK SIEARVKQIR
360 370 380 390 400
AQIEEATSDY DREKLQERVA KLAGGVAVIR VGAATEVEMK EKKARVEDAL
410 420 430 440 450
HATRAAVEEG VVPGGGVALL RAKQAITGLK GDTADQNAGI KLILRAVEEP
460 470 480 490 500
LRTIVTNAGD EASVVVNTVL NGKGNYGYNA ATGEYGDLVE QGVLDPTKVT
510 520 530 540
RTALQNAASV ASLLLTAEAA VVELMENKPA AAPAMPGGMG GMGGMDF
Length:547
Mass (Da):57,482
Last modified:February 1, 1996 - v1
Checksum:iF780D0401F63CF3F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U12277 Genomic DNA. Translation: AAA74967.1.
BX640421 Genomic DNA. Translation: CAE43756.1.
PIRiI40331.
RefSeqiNP_882014.1. NC_002929.2.
WP_010931507.1. NC_002929.2.

Genome annotation databases

EnsemblBacteriaiCAE43756; CAE43756; BP3495.
GeneIDi2664893.
KEGGibpe:BP3495.
PATRICifig|257313.5.peg.3784.

Similar proteinsi

Entry informationi

Entry nameiCH60_BORPE
AccessioniPrimary (citable) accession number: P48210
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: November 22, 2017
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families