Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P48167

- GLRB_HUMAN

UniProt

P48167 - GLRB_HUMAN

Protein

Glycine receptor subunit beta

Gene

GLRB

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 142 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).

    GO - Molecular functioni

    1. extracellular-glycine-gated chloride channel activity Source: Reactome
    2. extracellular-glycine-gated ion channel activity Source: UniProtKB
    3. glycine binding Source: Ensembl
    4. protein binding Source: UniProtKB

    GO - Biological processi

    1. acrosome reaction Source: Ensembl
    2. adult walking behavior Source: Ensembl
    3. chloride transmembrane transport Source: GOC
    4. ion transmembrane transport Source: Reactome
    5. ion transport Source: UniProtKB
    6. nervous system development Source: UniProtKB
    7. neuropeptide signaling pathway Source: UniProtKB
    8. protein heterooligomerization Source: Ensembl
    9. regulation of membrane potential Source: Ensembl
    10. righting reflex Source: Ensembl
    11. startle response Source: UniProtKB
    12. synaptic transmission Source: UniProtKB
    13. synaptic transmission, glycinergic Source: Ensembl
    14. transmembrane transport Source: Reactome
    15. visual perception Source: Ensembl

    Keywords - Molecular functioni

    Chloride channel, Ion channel, Ligand-gated ion channel, Receptor

    Keywords - Biological processi

    Ion transport, Transport

    Keywords - Ligandi

    Chloride

    Enzyme and pathway databases

    ReactomeiREACT_25387. Ligand-gated ion channel transport.

    Protein family/group databases

    TCDBi1.A.9.3.1. the neurotransmitter receptor, cys loop, ligand-gated ion channel (lic) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glycine receptor subunit beta
    Alternative name(s):
    Glycine receptor 58 kDa subunit
    Gene namesi
    Name:GLRB
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 4

    Organism-specific databases

    HGNCiHGNC:4329. GLRB.

    Subcellular locationi

    GO - Cellular componenti

    1. cell junction Source: UniProtKB-KW
    2. chloride channel complex Source: UniProtKB-KW
    3. integral component of plasma membrane Source: UniProtKB
    4. plasma membrane Source: Reactome
    5. postsynaptic membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell junction, Cell membrane, Membrane, Postsynaptic cell membrane, Synapse

    Pathology & Biotechi

    Involvement in diseasei

    Hyperekplexia 2 (HKPX2) [MIM:614619]: A neurologic disorder characterized by muscular rigidity of central nervous system origin, particularly in the neonatal period, and by an exaggerated startle response to unexpected acoustic or tactile stimuli.2 Publications
    Note: The disease is caused by mutations affecting the gene represented in this entry.
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti199 – 1991M → R in HKPX2. 1 Publication
    VAR_068246
    Natural varianti251 – 2511G → D in HKPX2. 1 Publication
    VAR_035070

    Keywords - Diseasei

    Disease mutation

    Organism-specific databases

    MIMi614619. phenotype.
    Orphaneti3197. Hereditary hyperekplexia.
    PharmGKBiPA28730.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2222By similarityAdd
    BLAST
    Chaini23 – 497475Glycine receptor subunit betaPRO_0000000423Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi54 – 541N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi183 ↔ 197By similarity
    Glycosylationi242 – 2421N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    PaxDbiP48167.
    PRIDEiP48167.

    PTM databases

    PhosphoSiteiP48167.

    Expressioni

    Gene expression databases

    ArrayExpressiP48167.
    BgeeiP48167.
    CleanExiHS_GLRB.
    GenevestigatoriP48167.

    Organism-specific databases

    HPAiHPA052363.

    Interactioni

    Subunit structurei

    Interacts with GPHN By similarity. Pentamer composed of three alpha and two beta subunits.By similarity1 Publication

    Protein-protein interaction databases

    BioGridi109005. 1 interaction.
    STRINGi9606.ENSP00000264428.

    Structurei

    3D structure databases

    ProteinModelPortaliP48167.
    SMRiP48167. Positions 55-374.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini23 – 265243ExtracellularCuratedAdd
    BLAST
    Topological domaini355 – 478124CytoplasmicCuratedAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei266 – 29025HelicalCuratedAdd
    BLAST
    Transmembranei299 – 31618HelicalCuratedAdd
    BLAST
    Transmembranei331 – 35424HelicalCuratedAdd
    BLAST
    Transmembranei479 – 49618HelicalCuratedAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG295166.
    HOGENOMiHOG000231336.
    HOVERGENiHBG051707.
    InParanoidiP48167.
    KOiK05196.
    OMAiPTMFKCL.
    OrthoDBiEOG712TVZ.
    PhylomeDBiP48167.
    TreeFamiTF315453.

    Family and domain databases

    Gene3Di2.70.170.10. 1 hit.
    InterProiIPR008060. Glycine_rcpt_B.
    IPR006202. Neur_chan_lig-bd.
    IPR006201. Neur_channel.
    IPR006029. Neurotrans-gated_channel_TM.
    IPR018000. Neurotransmitter_ion_chnl_CS.
    [Graphical view]
    PANTHERiPTHR18945. PTHR18945. 1 hit.
    PTHR18945:SF29. PTHR18945:SF29. 1 hit.
    PfamiPF02931. Neur_chan_LBD. 1 hit.
    PF02932. Neur_chan_memb. 1 hit.
    [Graphical view]
    PRINTSiPR01677. GLYRBETA.
    PR00252. NRIONCHANNEL.
    SUPFAMiSSF63712. SSF63712. 1 hit.
    SSF90112. SSF90112. 1 hit.
    TIGRFAMsiTIGR00860. LIC. 1 hit.
    PROSITEiPS00236. NEUROTR_ION_CHANNEL. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: P48167-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MKFLLTTAFL ILISLWVEEA YSKEKSSKKG KGKKKQYLCP SQQSAEDLAR    50
    VPANSTSNIL NRLLVSYDPR IRPNFKGIPV DVVVNIFINS FGSIQETTMD 100
    YRVNIFLRQK WNDPRLKLPS DFRGSDALTV DPTMYKCLWK PDLFFANEKS 150
    ANFHDVTQEN ILLFIFRDGD VLVSMRLSIT LSCPLDLTLF PMDTQRCKMQ 200
    LESFGYTTDD LRFIWQSGDP VQLEKIALPQ FDIKKEDIEY GNCTKYYKGT 250
    GYYTCVEVIF TLRRQVGFYM MGVYAPTLLI VVLSWLSFWI NPDASAARVP 300
    LGIFSVLSLA SECTTLAAEL PKVSYVKALD VWLIACLLFG FASLVEYAVV 350
    QVMLNNPKRV EAEKARIAKA EQADGKGGNV AKKNTVNGTG TPVHISTLQV 400
    GETRCKKVCT SKSDLRSNDF SIVGSLPRDF ELSNYDCYGK PIEVNNGLGK 450
    SQAKNNKKPP PAKPVIPTAA KRIDLYARAL FPFCFLFFNV IYWSIYL 497
    Length:497
    Mass (Da):56,122
    Last modified:February 1, 1996 - v1
    Checksum:iC1F0B407601D3625
    GO
    Isoform 2 (identifier: P48167-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         303-303: I → W
         304-497: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:303
    Mass (Da):34,944
    Checksum:iD1CAB208A3C5B6C3
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti199 – 1991M → R in HKPX2. 1 Publication
    VAR_068246
    Natural varianti251 – 2511G → D in HKPX2. 1 Publication
    VAR_035070

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei303 – 3031I → W in isoform 2. 1 PublicationVSP_045466
    Alternative sequencei304 – 497194Missing in isoform 2. 1 PublicationVSP_045467Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U33267 mRNA. Translation: AAB37750.1.
    AF094754 mRNA. Translation: AAC71033.1.
    AF094755 mRNA. Translation: AAC71034.1.
    CD013911 mRNA. No translation available.
    AK290617 mRNA. Translation: BAF83306.1.
    AC079403 Genomic DNA. No translation available.
    CH471056 Genomic DNA. Translation: EAX04872.1.
    CH471056 Genomic DNA. Translation: EAX04873.1.
    BC032635 mRNA. Translation: AAH32635.1.
    CCDSiCCDS3796.1. [P48167-1]
    CCDS54813.1. [P48167-2]
    PIRiG02031.
    RefSeqiNP_000815.1. NM_000824.4. [P48167-1]
    NP_001159532.1. NM_001166060.1. [P48167-1]
    NP_001159533.1. NM_001166061.1. [P48167-2]
    UniGeneiHs.32973.

    Genome annotation databases

    EnsembliENST00000264428; ENSP00000264428; ENSG00000109738. [P48167-1]
    ENST00000509282; ENSP00000427186; ENSG00000109738. [P48167-1]
    ENST00000541722; ENSP00000441873; ENSG00000109738. [P48167-2]
    GeneIDi2743.
    KEGGihsa:2743.
    UCSCiuc003ipj.2. human. [P48167-1]

    Polymorphism databases

    DMDMi1346173.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U33267 mRNA. Translation: AAB37750.1 .
    AF094754 mRNA. Translation: AAC71033.1 .
    AF094755 mRNA. Translation: AAC71034.1 .
    CD013911 mRNA. No translation available.
    AK290617 mRNA. Translation: BAF83306.1 .
    AC079403 Genomic DNA. No translation available.
    CH471056 Genomic DNA. Translation: EAX04872.1 .
    CH471056 Genomic DNA. Translation: EAX04873.1 .
    BC032635 mRNA. Translation: AAH32635.1 .
    CCDSi CCDS3796.1. [P48167-1 ]
    CCDS54813.1. [P48167-2 ]
    PIRi G02031.
    RefSeqi NP_000815.1. NM_000824.4. [P48167-1 ]
    NP_001159532.1. NM_001166060.1. [P48167-1 ]
    NP_001159533.1. NM_001166061.1. [P48167-2 ]
    UniGenei Hs.32973.

    3D structure databases

    ProteinModelPortali P48167.
    SMRi P48167. Positions 55-374.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 109005. 1 interaction.
    STRINGi 9606.ENSP00000264428.

    Chemistry

    ChEMBLi CHEMBL2363052.
    DrugBanki DB00228. Enflurane.
    DB00145. Glycine.
    DB00431. Lindane.
    GuidetoPHARMACOLOGYi 427.

    Protein family/group databases

    TCDBi 1.A.9.3.1. the neurotransmitter receptor, cys loop, ligand-gated ion channel (lic) family.

    PTM databases

    PhosphoSitei P48167.

    Polymorphism databases

    DMDMi 1346173.

    Proteomic databases

    PaxDbi P48167.
    PRIDEi P48167.

    Protocols and materials databases

    DNASUi 2743.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000264428 ; ENSP00000264428 ; ENSG00000109738 . [P48167-1 ]
    ENST00000509282 ; ENSP00000427186 ; ENSG00000109738 . [P48167-1 ]
    ENST00000541722 ; ENSP00000441873 ; ENSG00000109738 . [P48167-2 ]
    GeneIDi 2743.
    KEGGi hsa:2743.
    UCSCi uc003ipj.2. human. [P48167-1 ]

    Organism-specific databases

    CTDi 2743.
    GeneCardsi GC04P157997.
    GeneReviewsi GLRB.
    HGNCi HGNC:4329. GLRB.
    HPAi HPA052363.
    MIMi 138492. gene.
    614619. phenotype.
    neXtProti NX_P48167.
    Orphaneti 3197. Hereditary hyperekplexia.
    PharmGKBi PA28730.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG295166.
    HOGENOMi HOG000231336.
    HOVERGENi HBG051707.
    InParanoidi P48167.
    KOi K05196.
    OMAi PTMFKCL.
    OrthoDBi EOG712TVZ.
    PhylomeDBi P48167.
    TreeFami TF315453.

    Enzyme and pathway databases

    Reactomei REACT_25387. Ligand-gated ion channel transport.

    Miscellaneous databases

    GeneWikii GLRB.
    GenomeRNAii 2743.
    NextBioi 10812.
    PROi P48167.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P48167.
    Bgeei P48167.
    CleanExi HS_GLRB.
    Genevestigatori P48167.

    Family and domain databases

    Gene3Di 2.70.170.10. 1 hit.
    InterProi IPR008060. Glycine_rcpt_B.
    IPR006202. Neur_chan_lig-bd.
    IPR006201. Neur_channel.
    IPR006029. Neurotrans-gated_channel_TM.
    IPR018000. Neurotransmitter_ion_chnl_CS.
    [Graphical view ]
    PANTHERi PTHR18945. PTHR18945. 1 hit.
    PTHR18945:SF29. PTHR18945:SF29. 1 hit.
    Pfami PF02931. Neur_chan_LBD. 1 hit.
    PF02932. Neur_chan_memb. 1 hit.
    [Graphical view ]
    PRINTSi PR01677. GLYRBETA.
    PR00252. NRIONCHANNEL.
    SUPFAMi SSF63712. SSF63712. 1 hit.
    SSF90112. SSF90112. 1 hit.
    TIGRFAMsi TIGR00860. LIC. 1 hit.
    PROSITEi PS00236. NEUROTR_ION_CHANNEL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes."
      Handford C.A., Lynch J.W., Baker E., Webb G.C., Ford J.H., Sutherland G.R., Schofield P.R.
      Brain Res. Mol. Brain Res. 35:211-219(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
      Tissue: Hippocampus.
    2. "The human glycine receptor beta subunit gene (GLRB): structure, refined chromosomal localization, and population polymorphism."
      Milani N., Muelhardt C., Weber R.G., Lichter P., Kioschis P., Poustka A., Becker C.-M.
      Genomics 50:341-345(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    3. "PCR isolation and cloning of novel splice variant mRNAs from known drug target genes."
      Jin P., Fu G.K., Wilson A.D., Yang J., Chien D., Hawkins P.R., Au-Young J., Stuve L.L.
      Genomics 83:566-571(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Heart.
    5. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Brain.
    8. "Stoichiometry of the human glycine receptor revealed by direct subunit counting."
      Durisic N., Godin A.G., Wever C.M., Heyes C.D., Lakadamyali M., Dent J.A.
      J. Neurosci. 32:12915-12920(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBUNIT STOICHIOMETRY.
    9. "Hyperekplexia associated with compound heterozygote mutations in the beta-subunit of the human inhibitory glycine receptor (GLRB)."
      Rees M.I., Lewis T.M., Kwok J.B.J., Mortier G.R., Govaert P., Snell R.G., Schofield P.R., Owen M.J.
      Hum. Mol. Genet. 11:853-860(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: VARIANT HKPX2 ASP-251.
    10. Cited for: VARIANT HKPX2 ARG-199.

    Entry informationi

    Entry nameiGLRB_HUMAN
    AccessioniPrimary (citable) accession number: P48167
    Secondary accession number(s): A8K3K2, D3DP23, F5GWE1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 142 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 4
      Human chromosome 4: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3