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P48164

- RS7B_YEAST

UniProt

P48164 - RS7B_YEAST

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Protein

40S ribosomal protein S7-B

Gene
RPS7B, YNL096C, N2212
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.1 Publication

GO - Molecular functioni

  1. structural constituent of ribosome Source: SGD

GO - Biological processi

  1. cytoplasmic translation Source: SGD
  2. ribosome biogenesis Source: SGD
  3. rRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Biological processi

Ribosome biogenesis, rRNA processing

Enzyme and pathway databases

BioCyciYEAST:G3O-33124-MONOMER.
ReactomeiREACT_188965. SRP-dependent cotranslational protein targeting to membrane.
REACT_189050. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_189183. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_217188. Formation of a pool of free 40S subunits.

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S7-B
Gene namesi
Name:RPS7B
Ordered Locus Names:YNL096C
ORF Names:N2212
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XIV

Organism-specific databases

CYGDiYNL096c.
SGDiS000005040. RPS7B.

Subcellular locationi

Cytoplasm. Nucleusnucleolus 2 Publications

GO - Cellular componenti

  1. cytosolic small ribosomal subunit Source: SGD
  2. nucleolus Source: UniProtKB-SubCell
  3. small-subunit processome Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 19018940S ribosomal protein S7-BPRO_0000174213Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylserine1 Publication
Modified residuei10 – 101Phosphoserine2 Publications
Modified residuei31 – 311Phosphoserine2 Publications

Post-translational modificationi

N-terminally acetylated by acetyltransferase NatA.1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiP48164.
PaxDbiP48164.
PeptideAtlasiP48164.

Expressioni

Gene expression databases

GenevestigatoriP48164.

Interactioni

Subunit structurei

Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with snoRNA U3. Interacts with MPP10. Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.2 Publications

Protein-protein interaction databases

BioGridi35728. 108 interactions.
DIPiDIP-3841N.
IntActiP48164. 10 interactions.
MINTiMINT-8285416.
STRINGi4932.YNL096C.

Structurei

3D structure databases

ProteinModelPortaliP48164.
SMRiP48164. Positions 5-187.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG280542.
GeneTreeiENSGT00390000014122.
HOGENOMiHOG000197237.
KOiK02993.
OMAiFELETSH.
OrthoDBiEOG7P02W9.

Family and domain databases

InterProiIPR000554. Ribosomal_S7e.
[Graphical view]
PANTHERiPTHR11278. PTHR11278. 1 hit.
PfamiPF01251. Ribosomal_S7e. 1 hit.
[Graphical view]
PROSITEiPS00948. RIBOSOMAL_S7E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P48164-1 [UniParc]FASTAAdd to Basket

« Hide

MSSVQSKILS QAPSELELQV AKTFIDLESS SPELKADLRP LQIKSIREID    50
VTGGKKALVL FVPVPALSAY HKVQTKLTRE LEKKFPDRHV IFLAERRILP 100
KPSRTSRQVQ KRPRSRTLTA VHDKVLEDMV FPTEIVGKRV RYLVGGNKIQ 150
KVLLDSKDVQ QIDYKLESFQ AVYNKLTGKQ IVFEIPSQTN 190
Length:190
Mass (Da):21,634
Last modified:February 1, 1996 - v1
Checksum:i46553FB74A5FAF4B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X85811 Genomic DNA. Translation: CAA59821.1.
Z71372 Genomic DNA. Translation: CAA95972.1.
BK006947 Genomic DNA. Translation: DAA10450.1.
PIRiS52729.
RefSeqiNP_014303.3. NM_001182934.3.

Genome annotation databases

EnsemblFungiiYNL096C; YNL096C; YNL096C.
GeneIDi855628.
KEGGisce:YNL096C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X85811 Genomic DNA. Translation: CAA59821.1 .
Z71372 Genomic DNA. Translation: CAA95972.1 .
BK006947 Genomic DNA. Translation: DAA10450.1 .
PIRi S52729.
RefSeqi NP_014303.3. NM_001182934.3.

3D structure databases

ProteinModelPortali P48164.
SMRi P48164. Positions 5-187.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 35728. 108 interactions.
DIPi DIP-3841N.
IntActi P48164. 10 interactions.
MINTi MINT-8285416.
STRINGi 4932.YNL096C.

Proteomic databases

MaxQBi P48164.
PaxDbi P48164.
PeptideAtlasi P48164.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YNL096C ; YNL096C ; YNL096C .
GeneIDi 855628.
KEGGi sce:YNL096C.

Organism-specific databases

CYGDi YNL096c.
SGDi S000005040. RPS7B.

Phylogenomic databases

eggNOGi NOG280542.
GeneTreei ENSGT00390000014122.
HOGENOMi HOG000197237.
KOi K02993.
OMAi FELETSH.
OrthoDBi EOG7P02W9.

Enzyme and pathway databases

BioCyci YEAST:G3O-33124-MONOMER.
Reactomei REACT_188965. SRP-dependent cotranslational protein targeting to membrane.
REACT_189050. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_189183. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_217188. Formation of a pool of free 40S subunits.

Miscellaneous databases

NextBioi 979833.

Gene expression databases

Genevestigatori P48164.

Family and domain databases

InterProi IPR000554. Ribosomal_S7e.
[Graphical view ]
PANTHERi PTHR11278. PTHR11278. 1 hit.
Pfami PF01251. Ribosomal_S7e. 1 hit.
[Graphical view ]
PROSITEi PS00948. RIBOSOMAL_S7E. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence analysis of a 14.2 kb fragment of Saccharomyces cerevisiae chromosome XIV that includes the ypt53, tRNALeu and gsr m2 genes and four new open reading frames."
    Garcia-Cantalejo J.M., Boskovic J., Jimenez A.
    Yeast 12:599-608(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 96604 / S288c / FY1679.
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
    Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J.
    , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
    Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. "The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae."
    Planta R.J., Mager W.H.
    Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NOMENCLATURE, SUBUNIT.
  5. "The action of N-terminal acetyltransferases on yeast ribosomal proteins."
    Arnold R.J., Polevoda B., Reilly J.P., Sherman F.
    J. Biol. Chem. 274:37035-37040(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: CLEAVAGE OF INITIATOR METHIONINE, ACETYLATION AT SER-2 BY NATA.
  6. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  7. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  8. "The small-subunit processome is a ribosome assembly intermediate."
    Bernstein K.A., Gallagher J.E.G., Mitchell B.M., Granneman S., Baserga S.J.
    Eukaryot. Cell 3:1619-1626(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH MPP10 AND SNORNA U3, IDENTIFICATION IN SSU PROCESSOME, SUBCELLULAR LOCATION.
  9. "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
    Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
    J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-31, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Strain: ADR376.
  10. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
    Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
    Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-10, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  11. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-10 AND SER-31, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiRS7B_YEAST
AccessioniPrimary (citable) accession number: P48164
Secondary accession number(s): D6W184
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: September 3, 2014
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 43500 molecules/cell in log phase SD medium.
There are 2 genes for S7 in yeast.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

External Data

Dasty 3

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