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Protein

40S ribosomal protein S7-B

Gene

RPS7B

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102). eS7 is involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (PubMed:15590835).1 Publication1 Publication

Miscellaneous

Present with 43500 molecules/cell in log phase SD medium.1 Publication
There are 2 genes for eS7 in yeast.Curated

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • cytoplasmic translation Source: SGD
  • ribosome biogenesis Source: SGD
  • rRNA processing Source: UniProtKB-KW

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein
Biological processRibosome biogenesis, rRNA processing

Enzyme and pathway databases

BioCyciYEAST:G3O-33124-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S7-B1 Publication
Alternative name(s):
Small ribosomal subunit protein eS7-B1 Publication
Gene namesi
Name:RPS7B1 Publication
Ordered Locus Names:YNL096C
ORF Names:N2212
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNL096C.
SGDiS000005040. RPS7B.

Subcellular locationi

GO - Cellular componenti

  • cytosolic small ribosomal subunit Source: SGD
  • nucleolus Source: UniProtKB-SubCell
  • small-subunit processome Source: SGD

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001742132 – 19040S ribosomal protein S7-BAdd BLAST189

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserine1 Publication1
Modified residuei10PhosphoserineCombined sources1
Modified residuei31PhosphoserineCombined sources1
Cross-linki124Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)By similarity

Post-translational modificationi

N-terminally acetylated by acetyltransferase NatA.1 Publication

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

MaxQBiP48164.
PRIDEiP48164.

PTM databases

iPTMnetiP48164.

Interactioni

Subunit structurei

Component of the small ribosomal subunit (SSU). Mature yeast ribosomes consist of a small (40S) and a large (60S) subunit. The 40S small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33 different proteins (encoded by 57 genes). The large 60S subunit contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different proteins (encoded by 81 genes) (PubMed:9559554, PubMed:22096102). Interacts with snoRNA U3. uS11 interacts with MPP10. Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3 (PubMed:15590835).1 Publication2 Publications

Protein-protein interaction databases

BioGridi35728. 168 interactors.
DIPiDIP-3841N.
IntActiP48164. 12 interactors.
MINTiMINT-8285416.

Structurei

3D structure databases

ProteinModelPortaliP48164.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000197237.
InParanoidiP48164.
KOiK02993.
OMAiHEAYLED.
OrthoDBiEOG092C4XAM.

Family and domain databases

InterProiView protein in InterPro
IPR000554. Ribosomal_S7e.
PANTHERiPTHR11278. PTHR11278. 1 hit.
PfamiView protein in Pfam
PF01251. Ribosomal_S7e. 1 hit.
PROSITEiView protein in PROSITE
PS00948. RIBOSOMAL_S7E. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P48164-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSVQSKILS QAPSELELQV AKTFIDLESS SPELKADLRP LQIKSIREID
60 70 80 90 100
VTGGKKALVL FVPVPALSAY HKVQTKLTRE LEKKFPDRHV IFLAERRILP
110 120 130 140 150
KPSRTSRQVQ KRPRSRTLTA VHDKVLEDMV FPTEIVGKRV RYLVGGNKIQ
160 170 180 190
KVLLDSKDVQ QIDYKLESFQ AVYNKLTGKQ IVFEIPSQTN
Length:190
Mass (Da):21,634
Last modified:February 1, 1996 - v1
Checksum:i46553FB74A5FAF4B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X85811 Genomic DNA. Translation: CAA59821.1.
Z71372 Genomic DNA. Translation: CAA95972.1.
BK006947 Genomic DNA. Translation: DAA10450.1.
PIRiS52729.
RefSeqiNP_014303.3. NM_001182934.3.

Genome annotation databases

EnsemblFungiiYNL096C; YNL096C; YNL096C.
GeneIDi855628.
KEGGisce:YNL096C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X85811 Genomic DNA. Translation: CAA59821.1.
Z71372 Genomic DNA. Translation: CAA95972.1.
BK006947 Genomic DNA. Translation: DAA10450.1.
PIRiS52729.
RefSeqiNP_014303.3. NM_001182934.3.

3D structure databases

ProteinModelPortaliP48164.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35728. 168 interactors.
DIPiDIP-3841N.
IntActiP48164. 12 interactors.
MINTiMINT-8285416.

PTM databases

iPTMnetiP48164.

Proteomic databases

MaxQBiP48164.
PRIDEiP48164.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYNL096C; YNL096C; YNL096C.
GeneIDi855628.
KEGGisce:YNL096C.

Organism-specific databases

EuPathDBiFungiDB:YNL096C.
SGDiS000005040. RPS7B.

Phylogenomic databases

HOGENOMiHOG000197237.
InParanoidiP48164.
KOiK02993.
OMAiHEAYLED.
OrthoDBiEOG092C4XAM.

Enzyme and pathway databases

BioCyciYEAST:G3O-33124-MONOMER.

Miscellaneous databases

PROiPR:P48164.

Family and domain databases

InterProiView protein in InterPro
IPR000554. Ribosomal_S7e.
PANTHERiPTHR11278. PTHR11278. 1 hit.
PfamiView protein in Pfam
PF01251. Ribosomal_S7e. 1 hit.
PROSITEiView protein in PROSITE
PS00948. RIBOSOMAL_S7E. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRS7B_YEAST
AccessioniPrimary (citable) accession number: P48164
Secondary accession number(s): D6W184
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: April 12, 2017
This is version 146 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.