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Protein

40S ribosomal protein S15Aa

Gene

RpS15Aa

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: FlyBase

GO - Biological processi

  • mitotic spindle elongation Source: FlyBase
  • mitotic spindle organization Source: FlyBase
  • translation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DME-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DME-6791226. Major pathway of rRNA processing in the nucleolus.
R-DME-72649. Translation initiation complex formation.
R-DME-72689. Formation of a pool of free 40S subunits.
R-DME-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-DME-72702. Ribosomal scanning and start codon recognition.
R-DME-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DME-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DME-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S15Aa
Gene namesi
Name:RpS15Aa
Synonyms:RpS15A
ORF Names:CG2033
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0010198. RpS15Aa.

Subcellular locationi

GO - Cellular componenti

  • ribosome Source: FlyBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 13012940S ribosomal protein S15AaPRO_0000126609Add
BLAST

Proteomic databases

PaxDbiP48149.
PRIDEiP48149.

Expressioni

Gene expression databases

BgeeiFBgn0010198.
GenevisibleiP48149. DM.

Interactioni

Protein-protein interaction databases

BioGridi68867. 16 interactions.
DIPiDIP-17180N.
IntActiP48149. 7 interactions.
MINTiMINT-1555889.
STRINGi7227.FBpp0073623.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4V6Welectron microscopy6.00AW1-130[»]
ProteinModelPortaliP48149.
SMRiP48149. Positions 2-130.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S8P family.Curated

Phylogenomic databases

eggNOGiKOG1754. Eukaryota.
COG0096. LUCA.
GeneTreeiENSGT00390000003021.
InParanoidiP48149.
KOiK02957.
OMAiWEKQFLP.
OrthoDBiEOG091G0TSE.
PhylomeDBiP48149.

Family and domain databases

InterProiIPR000630. Ribosomal_S8.
[Graphical view]
PANTHERiPTHR11758. PTHR11758. 1 hit.
PfamiPF00410. Ribosomal_S8. 1 hit.
[Graphical view]
SUPFAMiSSF56047. SSF56047. 1 hit.
PROSITEiPS00053. RIBOSOMAL_S8. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P48149-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRMNVLADA LKCINNAEKR GKRQVLLRPC SKVIIKFLTV MMKHGYIGEF
60 70 80 90 100
EIVDDHRSGK IVVNLTGRLN KCGVISPRFD VPINDIEKWT NNLLPSRQFG
110 120 130
YVVLTTSGGI MDHEEARRKH LGGKILGFFF
Length:130
Mass (Da):14,771
Last modified:January 23, 2007 - v2
Checksum:i41392F8F505DED09
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z21673 mRNA. Translation: CAA79771.1.
AE014298 Genomic DNA. Translation: AAF48256.1.
AE014298 Genomic DNA. Translation: AAF48257.1.
AE014298 Genomic DNA. Translation: AAN09322.1.
AE014298 Genomic DNA. Translation: AAN09323.1.
AY084182 mRNA. Translation: AAL89920.1.
PIRiS33498.
RefSeqiNP_001162738.1. NM_001169267.2.
NP_524709.1. NM_079970.6.
NP_727690.1. NM_167360.3.
NP_727692.1. NM_167362.3.
NP_727693.1. NM_167363.3.
UniGeneiDm.1427.

Genome annotation databases

EnsemblMetazoaiFBtr0073792; FBpp0073623; FBgn0010198.
FBtr0073793; FBpp0073624; FBgn0010198.
FBtr0073794; FBpp0073625; FBgn0010198.
FBtr0073795; FBpp0073626; FBgn0010198.
FBtr0300828; FBpp0290052; FBgn0010198.
GeneIDi44150.
KEGGidme:Dmel_CG2033.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z21673 mRNA. Translation: CAA79771.1.
AE014298 Genomic DNA. Translation: AAF48256.1.
AE014298 Genomic DNA. Translation: AAF48257.1.
AE014298 Genomic DNA. Translation: AAN09322.1.
AE014298 Genomic DNA. Translation: AAN09323.1.
AY084182 mRNA. Translation: AAL89920.1.
PIRiS33498.
RefSeqiNP_001162738.1. NM_001169267.2.
NP_524709.1. NM_079970.6.
NP_727690.1. NM_167360.3.
NP_727692.1. NM_167362.3.
NP_727693.1. NM_167363.3.
UniGeneiDm.1427.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4V6Welectron microscopy6.00AW1-130[»]
ProteinModelPortaliP48149.
SMRiP48149. Positions 2-130.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi68867. 16 interactions.
DIPiDIP-17180N.
IntActiP48149. 7 interactions.
MINTiMINT-1555889.
STRINGi7227.FBpp0073623.

Proteomic databases

PaxDbiP48149.
PRIDEiP48149.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0073792; FBpp0073623; FBgn0010198.
FBtr0073793; FBpp0073624; FBgn0010198.
FBtr0073794; FBpp0073625; FBgn0010198.
FBtr0073795; FBpp0073626; FBgn0010198.
FBtr0300828; FBpp0290052; FBgn0010198.
GeneIDi44150.
KEGGidme:Dmel_CG2033.

Organism-specific databases

CTDi44150.
FlyBaseiFBgn0010198. RpS15Aa.

Phylogenomic databases

eggNOGiKOG1754. Eukaryota.
COG0096. LUCA.
GeneTreeiENSGT00390000003021.
InParanoidiP48149.
KOiK02957.
OMAiWEKQFLP.
OrthoDBiEOG091G0TSE.
PhylomeDBiP48149.

Enzyme and pathway databases

ReactomeiR-DME-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DME-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DME-6791226. Major pathway of rRNA processing in the nucleolus.
R-DME-72649. Translation initiation complex formation.
R-DME-72689. Formation of a pool of free 40S subunits.
R-DME-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-DME-72702. Ribosomal scanning and start codon recognition.
R-DME-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DME-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DME-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

ChiTaRSiRpS15Aa. fly.
GenomeRNAii44150.
PROiP48149.

Gene expression databases

BgeeiFBgn0010198.
GenevisibleiP48149. DM.

Family and domain databases

InterProiIPR000630. Ribosomal_S8.
[Graphical view]
PANTHERiPTHR11758. PTHR11758. 1 hit.
PfamiPF00410. Ribosomal_S8. 1 hit.
[Graphical view]
SUPFAMiSSF56047. SSF56047. 1 hit.
PROSITEiPS00053. RIBOSOMAL_S8. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRS15A_DROME
AccessioniPrimary (citable) accession number: P48149
Secondary accession number(s): A4V4D9, Q9VYE4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.