P48064 (MTRB_BACPU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transcription attenuation protein MtrB

Alternative name(s):
Trp RNA-binding attenuation protein
Short name=TRAP
Tryptophan RNA-binding attenuator protein

Gene names

Name:

mtrB

Organism

Bacillus pumilus (Bacillus mesentericus)

Taxonomic identifier

1408 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	76 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan. HAMAP-Rule MF_00798
Subunit structure	Oligomer of 11 identical subunits arranged in doughnut-like structure By similarity.
Sequence similarities	Belongs to the MtrB family.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Ligand	RNA-binding
Gene Ontology (GO)
Biological_process	DNA-dependent transcription, termination Inferred from electronic annotation. Source: InterPro regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	RNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 76	76	Transcription attenuation protein MtrB HAMAP-Rule MF_00798		PRO_0000206026

Sequences

	Sequence		Length	Mass (Da)
	P48064 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: 22184B2351DA151D	FASTA	76	8,301
	10 20 30 40 50 60 MSENKASDFV VIKAIDNGVN VIGLTRGSDT RFHHSEKLDK GEVIIAQFTE HTSAIKVRGD 70 AVIQTSFGEI QSEAKK

References

[1]

"The mtrB gene of Bacillus pumilus encodes a protein with sequence and functional homology to the trp RNA-binding attenuation protein (TRAP) of Bacillus subtilis." Hoffman R.J., Gollnick P. J. Bacteriol. 177:839-842(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	L37879 Genomic DNA. Translation: AAA67544.1.
PIR	I39905.
3D structure databases
ProteinModelPortal	P48064.
SMR	P48064. Positions 8-75.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	2.60.40.50. 1 hit.
HAMAP	MF_00798. Trp_attenuator.
InterPro	IPR000824. Trp_RNA-bd_attenuator. IPR016031. Trp_RNA-bd_attenuator-like_dom. IPR023558. Trp_RNA-bd_attenuator_dom. [Graphical view]
Pfam	PF02081. TrpBP. 1 hit. [Graphical view]
PRINTS	PR00687. TRPRNAAP.
SUPFAM	SSF51219. TrpBP. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MTRB_BACPU

Accession

Primary (citable) accession number: P48064

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	April 3, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program