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Protein

Septin homolog spn5

Gene

spn5

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Septin-like protein involved in the correct orientation of forespore membrane extension during sporulation.1 Publication

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei151 – 1511GTPBy similarity
Binding sitei177 – 1771GTP; via amide nitrogenBy similarity
Binding sitei304 – 3041GTP; via amide nitrogen and carbonyl oxygenBy similarity
Binding sitei319 – 3191GTPBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi125 – 1328GTPBy similarity
Nucleotide bindingi257 – 2659GTPBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Meiosis, Sporulation

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Septin homolog spn5
Alternative name(s):
Mei4-dependent protein 9
Meiotic expression up-regulated protein 28
Gene namesi
Name:spn5
Synonyms:mde9, meu28
ORF Names:SPAC24C9.15c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC24C9.15c.
PomBaseiSPAC24C9.15c. spn5.

Subcellular locationi

GO - Cellular componenti

  • membrane Source: UniProtKB-KW
  • nucleus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 464464Septin homolog spn5PRO_0000173507Add
BLAST

Expressioni

Inductioni

Expressed during meiosis. Expresion is under the control of the meiosis-specific transcription factor mei4.1 Publication

Interactioni

Subunit structurei

Component of the sporulation-specific septin complex composed of at least spn2, spn5, spn6 and spn7.1 Publication

Protein-protein interaction databases

BioGridi279095. 12 interactions.
MINTiMINT-4690469.

Structurei

3D structure databases

ProteinModelPortaliP48010.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini115 – 370256Septin-type GAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili396 – 45358Sequence analysisAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Coiled coil

Phylogenomic databases

InParanoidiP48010.
OrthoDBiEOG092C3HL6.
PhylomeDBiP48010.

Family and domain databases

CDDicd01850. CDC_Septin. 1 hit.
Gene3Di3.40.50.300. 1 hit.
InterProiIPR030379. G_SEPTIN_dom.
IPR027417. P-loop_NTPase.
IPR016491. Septin.
[Graphical view]
PANTHERiPTHR18884. PTHR18884. 1 hit.
PfamiPF00735. Septin. 1 hit.
[Graphical view]
PIRSFiPIRSF006698. Septin. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS51719. G_SEPTIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P48010-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSSNLSSSM PQEGQLKLTE EAIITIKQVD ESSAKRSVSN ESRKSKDVTR
60 70 80 90 100
KEQIASDQQG DDQCPQSDTA KDKKTEFKQD EVPNSNGKSI PTFHPCNNIG
110 120 130 140 150
INDFNHQHYS RVCRNGIDIN LIVVGESSLG KTTFVNSFLQ SNDTNFRPKK
160 170 180 190 200
TMDFVEHKAT LSDGDQKFNL TIVDTPGFGD KSDNSNCWRP IATNLLHRLN
210 220 230 240 250
AYFQNEVKMD RETSEIDSRI HGCLFFINPN GHRLQPLEIY IMKKIDQFVN
260 270 280 290 300
IIPVIGKADT MTSDELNHFK KRVIADMVRE KIRYFREPHN EKKAKIPIPF
310 320 330 340 350
AIVGAGAPIE HDGKCIRGRA YPWGLVDIDD PKQSDFCQLR NFLLYTHIEG
360 370 380 390 400
LKHKTHKLIY DTFRTEKLVA LNATPGSQFI SAEEMNQKYI SEQTQLVEEA
410 420 430 440 450
LTKVMKEKYR EKENNLELLE TNLKTHHKDY KHALKKRITA LEEEKNRLIK
460
EIGPEKVKKA GILA
Length:464
Mass (Da):53,104
Last modified:July 15, 1998 - v2
Checksum:iF7BE83DE827ECE1B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U29891 Genomic DNA. Translation: AAB53688.2.
CU329670 Genomic DNA. Translation: CAB11273.1.
AB054312 mRNA. Translation: BAB60879.1.
PIRiT38356.
RefSeqiNP_594040.1. NM_001019465.2.

Genome annotation databases

EnsemblFungiiSPAC24C9.15c.1; SPAC24C9.15c.1:pep; SPAC24C9.15c.
GeneIDi2542641.
KEGGispo:SPAC24C9.15c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U29891 Genomic DNA. Translation: AAB53688.2.
CU329670 Genomic DNA. Translation: CAB11273.1.
AB054312 mRNA. Translation: BAB60879.1.
PIRiT38356.
RefSeqiNP_594040.1. NM_001019465.2.

3D structure databases

ProteinModelPortaliP48010.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279095. 12 interactions.
MINTiMINT-4690469.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC24C9.15c.1; SPAC24C9.15c.1:pep; SPAC24C9.15c.
GeneIDi2542641.
KEGGispo:SPAC24C9.15c.

Organism-specific databases

EuPathDBiFungiDB:SPAC24C9.15c.
PomBaseiSPAC24C9.15c. spn5.

Phylogenomic databases

InParanoidiP48010.
OrthoDBiEOG092C3HL6.
PhylomeDBiP48010.

Miscellaneous databases

PROiP48010.

Family and domain databases

CDDicd01850. CDC_Septin. 1 hit.
Gene3Di3.40.50.300. 1 hit.
InterProiIPR030379. G_SEPTIN_dom.
IPR027417. P-loop_NTPase.
IPR016491. Septin.
[Graphical view]
PANTHERiPTHR18884. PTHR18884. 1 hit.
PfamiPF00735. Septin. 1 hit.
[Graphical view]
PIRSFiPIRSF006698. Septin. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS51719. G_SEPTIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSPN5_SCHPO
AccessioniPrimary (citable) accession number: P48010
Secondary accession number(s): O13975, Q96WR7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: July 15, 1998
Last modified: September 7, 2016
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.