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P47955

- RLA1_MOUSE

UniProt

P47955 - RLA1_MOUSE

Protein

60S acidic ribosomal protein P1

Gene

Rplp1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    Plays an important role in the elongation step of protein synthesis.

    GO - Molecular functioni

    1. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translational elongation Source: InterPro

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Enzyme and pathway databases

    ReactomeiREACT_196445. SRP-dependent cotranslational protein targeting to membrane.
    REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    60S acidic ribosomal protein P1
    Gene namesi
    Name:Rplp1
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 9

    Organism-specific databases

    MGIiMGI:1927099. Rplp1.

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 11411360S acidic ribosomal protein P1PRO_0000157687Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylalanineBy similarity
    Modified residuei101 – 1011PhosphoserineBy similarity

    Keywords - PTMi

    Acetylation, Phosphoprotein

    Proteomic databases

    MaxQBiP47955.
    PaxDbiP47955.
    PRIDEiP47955.

    PTM databases

    PhosphoSiteiP47955.

    Expressioni

    Gene expression databases

    BgeeiP47955.
    CleanExiMM_RPLP1.
    GenevestigatoriP47955.

    Interactioni

    Subunit structurei

    Heterodimer with RPLP2 at the lateral ribosomal stalk of the large ribosomal subunit.By similarity

    Protein-protein interaction databases

    BioGridi207787. 11 interactions.
    IntActiP47955. 5 interactions.
    MINTiMINT-4132672.
    STRINGi10090.ENSMUSP00000008036.

    Structurei

    3D structure databases

    ProteinModelPortaliP47955.
    SMRiP47955. Positions 1-114.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L12P family.Curated

    Phylogenomic databases

    eggNOGiCOG2058.
    HOGENOMiHOG000229898.
    HOVERGENiHBG002291.
    InParanoidiP47955.
    KOiK02942.
    OMAiTSELACI.
    OrthoDBiEOG7M0NVC.
    PhylomeDBiP47955.
    TreeFamiTF312932.

    Family and domain databases

    HAMAPiMF_01478. Ribosomal_L12_arch.
    InterProiIPR001813. Ribosomal_L10/L12.
    IPR027534. Ribosomal_L12.
    [Graphical view]
    PfamiPF00428. Ribosomal_60s. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P47955-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASVSELACI YSALILHDDE VTVTEDKINA LIKAAGVSVE PFWPGLFAKA    50
    LANVNIGSLI CNVGAGGPAP AAGAAPAGGA APSTAAAPAE EKKVEAKKEE 100
    SEESEDDMGF GLFD 114
    Length:114
    Mass (Da):11,475
    Last modified:February 1, 1996 - v1
    Checksum:i63C344A2772350D2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U29402 mRNA. Translation: AAA70106.1.
    AK007832 mRNA. Translation: BAB25292.1.
    AK010656 mRNA. Translation: BAB27095.1.
    AK088070 mRNA. Translation: BAC40128.1.
    BC058685 mRNA. Translation: AAH58685.1.
    CCDSiCCDS23260.1.
    RefSeqiNP_061341.1. NM_018853.3.
    UniGeneiMm.3158.

    Genome annotation databases

    EnsembliENSMUST00000008036; ENSMUSP00000008036; ENSMUSG00000007892.
    GeneIDi56040.
    KEGGimmu:56040.
    UCSCiuc009pzt.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U29402 mRNA. Translation: AAA70106.1 .
    AK007832 mRNA. Translation: BAB25292.1 .
    AK010656 mRNA. Translation: BAB27095.1 .
    AK088070 mRNA. Translation: BAC40128.1 .
    BC058685 mRNA. Translation: AAH58685.1 .
    CCDSi CCDS23260.1.
    RefSeqi NP_061341.1. NM_018853.3.
    UniGenei Mm.3158.

    3D structure databases

    ProteinModelPortali P47955.
    SMRi P47955. Positions 1-114.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 207787. 11 interactions.
    IntActi P47955. 5 interactions.
    MINTi MINT-4132672.
    STRINGi 10090.ENSMUSP00000008036.

    PTM databases

    PhosphoSitei P47955.

    Proteomic databases

    MaxQBi P47955.
    PaxDbi P47955.
    PRIDEi P47955.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000008036 ; ENSMUSP00000008036 ; ENSMUSG00000007892 .
    GeneIDi 56040.
    KEGGi mmu:56040.
    UCSCi uc009pzt.1. mouse.

    Organism-specific databases

    CTDi 6176.
    MGIi MGI:1927099. Rplp1.

    Phylogenomic databases

    eggNOGi COG2058.
    HOGENOMi HOG000229898.
    HOVERGENi HBG002291.
    InParanoidi P47955.
    KOi K02942.
    OMAi TSELACI.
    OrthoDBi EOG7M0NVC.
    PhylomeDBi P47955.
    TreeFami TF312932.

    Enzyme and pathway databases

    Reactomei REACT_196445. SRP-dependent cotranslational protein targeting to membrane.
    REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

    Miscellaneous databases

    ChiTaRSi RpLP1. mouse.
    NextBioi 311800.
    PROi P47955.
    SOURCEi Search...

    Gene expression databases

    Bgeei P47955.
    CleanExi MM_RPLP1.
    Genevestigatori P47955.

    Family and domain databases

    HAMAPi MF_01478. Ribosomal_L12_arch.
    InterProi IPR001813. Ribosomal_L10/L12.
    IPR027534. Ribosomal_L12.
    [Graphical view ]
    Pfami PF00428. Ribosomal_60s. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Crowe D.L., Cui X.M., Shuler C.F.
      Submitted (JUN-1995) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    2. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Head and Pancreas.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6.
      Tissue: Brain.

    Entry informationi

    Entry nameiRLA1_MOUSE
    AccessioniPrimary (citable) accession number: P47955
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 106 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3