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P47955

- RLA1_MOUSE

UniProt

P47955 - RLA1_MOUSE

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Protein

60S acidic ribosomal protein P1

Gene

Rplp1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Plays an important role in the elongation step of protein synthesis.

GO - Molecular functioni

  1. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translational elongation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiREACT_196445. SRP-dependent cotranslational protein targeting to membrane.
REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S acidic ribosomal protein P1
Gene namesi
Name:Rplp1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 9

Organism-specific databases

MGIiMGI:1927099. Rplp1.

Subcellular locationi

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 11411360S acidic ribosomal protein P1PRO_0000157687Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanineBy similarity
Modified residuei101 – 1011PhosphoserineBy similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiP47955.
PaxDbiP47955.
PRIDEiP47955.

PTM databases

PhosphoSiteiP47955.

Expressioni

Gene expression databases

BgeeiP47955.
CleanExiMM_RPLP1.
ExpressionAtlasiP47955. baseline and differential.
GenevestigatoriP47955.

Interactioni

Subunit structurei

Heterodimer with RPLP2 at the lateral ribosomal stalk of the large ribosomal subunit.By similarity

Protein-protein interaction databases

BioGridi207787. 11 interactions.
IntActiP47955. 5 interactions.
MINTiMINT-4132672.
STRINGi10090.ENSMUSP00000008036.

Structurei

3D structure databases

ProteinModelPortaliP47955.
SMRiP47955. Positions 1-114.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L12P family.Curated

Phylogenomic databases

eggNOGiCOG2058.
HOGENOMiHOG000229898.
HOVERGENiHBG002291.
InParanoidiP47955.
KOiK02942.
OMAiTSELACI.
OrthoDBiEOG7M0NVC.
PhylomeDBiP47955.
TreeFamiTF312932.

Family and domain databases

HAMAPiMF_01478. Ribosomal_L12_arch.
InterProiIPR001813. Ribosomal_L10/L12.
IPR027534. Ribosomal_L12.
[Graphical view]
PfamiPF00428. Ribosomal_60s. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P47955-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASVSELACI YSALILHDDE VTVTEDKINA LIKAAGVSVE PFWPGLFAKA
60 70 80 90 100
LANVNIGSLI CNVGAGGPAP AAGAAPAGGA APSTAAAPAE EKKVEAKKEE
110
SEESEDDMGF GLFD
Length:114
Mass (Da):11,475
Last modified:February 1, 1996 - v1
Checksum:i63C344A2772350D2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U29402 mRNA. Translation: AAA70106.1.
AK007832 mRNA. Translation: BAB25292.1.
AK010656 mRNA. Translation: BAB27095.1.
AK088070 mRNA. Translation: BAC40128.1.
BC058685 mRNA. Translation: AAH58685.1.
CCDSiCCDS23260.1.
RefSeqiNP_061341.1. NM_018853.3.
UniGeneiMm.3158.

Genome annotation databases

EnsembliENSMUST00000008036; ENSMUSP00000008036; ENSMUSG00000007892.
GeneIDi56040.
KEGGimmu:56040.
UCSCiuc009pzt.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U29402 mRNA. Translation: AAA70106.1 .
AK007832 mRNA. Translation: BAB25292.1 .
AK010656 mRNA. Translation: BAB27095.1 .
AK088070 mRNA. Translation: BAC40128.1 .
BC058685 mRNA. Translation: AAH58685.1 .
CCDSi CCDS23260.1.
RefSeqi NP_061341.1. NM_018853.3.
UniGenei Mm.3158.

3D structure databases

ProteinModelPortali P47955.
SMRi P47955. Positions 1-114.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 207787. 11 interactions.
IntActi P47955. 5 interactions.
MINTi MINT-4132672.
STRINGi 10090.ENSMUSP00000008036.

PTM databases

PhosphoSitei P47955.

Proteomic databases

MaxQBi P47955.
PaxDbi P47955.
PRIDEi P47955.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000008036 ; ENSMUSP00000008036 ; ENSMUSG00000007892 .
GeneIDi 56040.
KEGGi mmu:56040.
UCSCi uc009pzt.1. mouse.

Organism-specific databases

CTDi 6176.
MGIi MGI:1927099. Rplp1.

Phylogenomic databases

eggNOGi COG2058.
HOGENOMi HOG000229898.
HOVERGENi HBG002291.
InParanoidi P47955.
KOi K02942.
OMAi TSELACI.
OrthoDBi EOG7M0NVC.
PhylomeDBi P47955.
TreeFami TF312932.

Enzyme and pathway databases

Reactomei REACT_196445. SRP-dependent cotranslational protein targeting to membrane.
REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

ChiTaRSi RpLP1. mouse.
NextBioi 311800.
PROi P47955.
SOURCEi Search...

Gene expression databases

Bgeei P47955.
CleanExi MM_RPLP1.
ExpressionAtlasi P47955. baseline and differential.
Genevestigatori P47955.

Family and domain databases

HAMAPi MF_01478. Ribosomal_L12_arch.
InterProi IPR001813. Ribosomal_L10/L12.
IPR027534. Ribosomal_L12.
[Graphical view ]
Pfami PF00428. Ribosomal_60s. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Crowe D.L., Cui X.M., Shuler C.F.
    Submitted (JUN-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Head and Pancreas.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6.
    Tissue: Brain.

Entry informationi

Entry nameiRLA1_MOUSE
AccessioniPrimary (citable) accession number: P47955
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: October 29, 2014
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3