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P47911 (RL6_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 100. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
60S ribosomal protein L6
Alternative name(s):
TAX-responsive enhancer element-binding protein 107
Short name=TAXREB107
Gene names
Name:Rpl6
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length296 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

May bind IPO9 with low affinity.

Sequence similarities

Belongs to the ribosomal protein L6e family.

Sequence caution

The sequence CAA57513.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 29629560S ribosomal protein L6
PRO_0000171010

Amino acid modifications

Modified residue1351Phosphoserine By similarity
Modified residue2261N6-acetyllysine By similarity
Modified residue2471N6-acetyllysine By similarity

Experimental info

Sequence conflict51K → R Ref.3
Sequence conflict101K → M in CAA57513. Ref.3
Sequence conflict751L → F in AAH62880. Ref.2

Sequences

Sequence LengthMass (Da)Tools
P47911 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: D65D5EF517660836

FASTA29633,510
        10         20         30         40         50         60 
MAGEKAPDTK EKKPAAKKAG SDAAASRPRA AKVAKKVHPK GKKPKKAKPH CSRNPVLVRG 

        70         80         90        100        110        120 
IGRYSRSAMY SRKALYKRKY SAAKTKVEKK KKKEKVLATV TKTVGGDKNG GTRVVKLRKM 

       130        140        150        160        170        180 
PRYYPTEDVP RKLLSHGKKP FSQHVRRLRS SITPGTVLII LTGRHRGKRV VFLKQLDSGL 

       190        200        210        220        230        240 
LLVTGPLVIN RVPLRRTHQK FVIATSTKVD ISDVKIPKHL TDAYFKKKQL RKPRHQEGEI 

       250        260        270        280        290 
FDTEKEKYEI TEQRKADQKA VDLQILPKIK AVPQLQGYLR SQFSLTNGMY PHKLVF 

« Hide

References

« Hide 'large scale' references
[1]Wang J.-S., Han H., Yang X., Li R., Zhou P.
Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 129/Sv.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6.
Tissue: Brain.
[3]"The mouse homologue of the HTLV-I tax responsive element binding protein TAXREB107 is a highly conserved gene which may regulate some basal cellular functions."
Nacken W., Klempt M., Sorg C.
Biochim. Biophys. Acta 1261:432-434(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 4-296.
[4]"Importins fulfill a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains."
Jaekel S., Mingot J.-M., Schwarzmaier P., Hartmann E., Goerlich D.
EMBO J. 21:377-386(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH IPO9.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF374195 Genomic DNA. Translation: AAK56936.1.
BC062880 mRNA. Translation: AAH62880.1.
X81987 mRNA. Translation: CAA57513.1. Different initiation.
PIRS55922.
RefSeqNP_035420.2. NM_011290.5.
XP_006530290.1. XM_006530227.1.
UniGeneMm.262021.

3D structure databases

ProteinModelPortalP47911.
SMRP47911. Positions 50-296.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid202987. 10 interactions.
IntActP47911. 7 interactions.
MINTMINT-1857899.

PTM databases

PhosphoSiteP47911.

Proteomic databases

PaxDbP47911.
PRIDEP47911.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000031617; ENSMUSP00000031617; ENSMUSG00000029614.
GeneID19988.
KEGGmmu:19988.
UCSCuc008ziq.3. mouse.

Organism-specific databases

CTD6128.
MGIMGI:108057. Rpl6.

Phylogenomic databases

eggNOGCOG2163.
HOGENOMHOG000207317.
HOVERGENHBG002565.
InParanoidP47911.
KOK02934.
OMAYELTEQR.
OrthoDBEOG78D7MH.
PhylomeDBP47911.
TreeFamTF300115.

Gene expression databases

BgeeP47911.
CleanExMM_RPL6.
GenevestigatorP47911.

Family and domain databases

Gene3D2.30.30.30. 1 hit.
InterProIPR000915. 60S_ribosomal_L6E.
IPR014722. Rib_L2_dom2.
IPR005568. Ribosomal_L6_N.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PANTHERPTHR10715. PTHR10715. 1 hit.
PfamPF01159. Ribosomal_L6e. 1 hit.
PF03868. Ribosomal_L6e_N. 1 hit.
[Graphical view]
SUPFAMSSF50104. SSF50104. 1 hit.
PROSITEPS01170. RIBOSOMAL_L6E. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio297499.
PROP47911.
SOURCESearch...

Entry information

Entry nameRL6_MOUSE
AccessionPrimary (citable) accession number: P47911
Secondary accession number(s): Q6P5I2, Q925C3
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: January 23, 2007
Last modified: April 16, 2014
This is version 100 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot