P47908 (LRTA_SYNP2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Light-repressed protein A

Alternative name(s):
Dark-response protein 21
Short name=DRP-21

Gene names

Name:	lrtA
Ordered Locus Names:	SYNPCC7002_A0263

Organism

Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum) [Complete proteome] [HAMAP]

Taxonomic identifier

32049 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechococcus

Protein attributes

Sequence length	193 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Might modulate either transcription and/or translation. Ref.3
Induction	Is repressed by light, since the transcript is synthesized in the dark, but upon 20 minutes of illumination, transcript levels fall below detectable limits. This light-repressed transcript is present only in dark-adapted cells. Is rapidly translated at the onset of illumination; in fact, is one of the first proteins to be synthesized upon illumination of dark-adapted cells. Repression of the transcript in the light requires protein synthesis, which suggests that a specific protein is directly involved in lrtA light repression. Ref.1 Ref.3
Disruption phenotype	Knockout mutants of lrtA grown in continuous light appear to be the same as wild-type, showing no differences in growth or photosynthetic activity. Ref.1
Miscellaneous	The transcript for lrtA is more stable in the dark than in the light: a 3-hours half-life is estimated in the dark, whereas a 4-minutes half-life is observed in the light.
Sequence similarities	Belongs to the ribosomal protein S30Ae family.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	primary metabolic process Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 193	193	Light-repressed protein A		PRO_0000208587
Experimental info
	Sequence conflict	122 – 131	10	LIGDRAPELP → SLRSRPRAS in AAA62586. Ref.1
	Sequence conflict	149	1	E → Q in AAA62586. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P47908 [UniParc]. Last modified June 10, 2008. Version 2. Checksum: 6521B45874951D98	FASTA	193	21,911
	10 20 30 40 50 60 MKLLIQGNNI AVTESIHDYV ESKLEKATKH FQTFATKVDV HLSVANNARI TDKHKAEVTV 70 80 90 100 110 120 YANGTVIRAQ EGSENLYASI DLVSDKIARQ LRKYKEKNFG KKTHVQEKTS EVLPEDPVPD 130 140 150 160 170 180 NLIGDRAPEL PSEVVRMKYF AMPPMTIDEA LEQLQLVDHD FYMFLNKDTN AINVIYIRNH 190 GGYGVIQPRL GKE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A light-repressed transcript found in Synechococcus PCC 7002 is similar to a chloroplast-specific small subunit ribosomal protein and to a transcription modulator protein associated with sigma 54." Tan X., Varughese M., Widger W.R. J. Biol. Chem. 269:20905-20912(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], INDUCTION, DISRUPTION PHENOTYPE. Strain: ATCC 27264 / PCC 7002 / PR-6.
[2]	"Complete sequence of Synechococcus sp. PCC 7002." Li T., Zhao J., Zhao C., Liu Z., Zhao F., Marquardt J., Nomura C.T., Persson S., Detter J.C., Richardson P.M., Lanz C., Schuster S.C., Wang J., Li S., Huang X., Cai T., Yu Z., Luo J., Zhao J., Bryant D.A. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27264 / PCC 7002 / PR-6.
[3]	"Transcriptional and posttranscriptional control of mRNA from lrtA, a light-repressed transcript in Synechococcus sp. PCC 7002." Samartzidou H., Widger W.R. Plant Physiol. 117:225-234(1998) [PubMed] [Europe PMC] [Abstract] Cited for: INDUCTION, PUTATIVE FUNCTION. Strain: ATCC 27264 / PCC 7002 / PR-6.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L29194 Genomic DNA. Translation: AAA62586.1. CP000951 Genomic DNA. Translation: ACA98273.1.
PIR	A53914.
RefSeq	YP_001733529.1. NC_010475.1.
3D structure databases
ProteinModelPortal	P47908.
ModBase	Search...
Protein-protein interaction databases
STRING	32049.SYNPCC7002_A0263.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACA98273; ACA98273; SYNPCC7002_A0263.
GeneID	6057840.
KEGG	syp:SYNPCC7002_A0263.
PATRIC	23814962. VBISynSp37135_0444.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1544.
HOGENOM	HOG000074929.
KO	K05808.
OMA	NVEVPEH.
ProtClustDB	CLSK893348.
Family and domain databases
Gene3D	3.30.160.100. 1 hit.
InterPro	IPR003489. Ribosomal_S30Ae/sigma54_mod. [Graphical view]
Pfam	PF02482. Ribosomal_S30AE. 1 hit. [Graphical view]
SUPFAM	SSF69754. Ribosomal_S30Ae/sigma54_mod. 1 hit.
TIGRFAMs	TIGR00741. yfiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

LRTA_SYNP2

Accession

Primary (citable) accession number: P47908
Secondary accession number(s): B1XMT6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	June 10, 2008
Last modified:	May 1, 2013
This is version 56 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program