ID   OMP_HUMAN               Reviewed;         163 AA.
AC   P47874; Q562G2;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   14-DEC-2011, entry version 77.
DE   RecName: Full=Olfactory marker protein;
DE   AltName: Full=Olfactory neuronal-specific protein;
GN   Name=OMP;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   MEDLINE=94307732; PubMed=8034318; DOI=10.1006/geno.1994.1200;
RA   Buiakova O.I., Rama Krishna N.S., Getchell T.V., Margolis F.L.;
RT   "Human and rodent OMP genes: conservation of structural and regulatory
RT   motifs and cellular localization.";
RL   Genomics 20:452-462(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May act as a modulator of the olfactory signal-
CC       transduction cascade.
CC   -!- SUBUNIT: Interacts with BEX1 and BEX2 (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- TISSUE SPECIFICITY: Uniquely associated with mature olfactory
CC       receptor neurons.
CC   -!- SIMILARITY: Belongs to the olfactory marker protein family.
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DR   EMBL; U01212; AAA20485.1; -; Genomic_DNA.
DR   EMBL; BC069115; AAH69115.1; -; mRNA.
DR   EMBL; BC069365; AAH69365.1; -; mRNA.
DR   IPI; IPI00220343; -.
DR   PIR; A54261; A54261.
DR   RefSeq; NP_006180.1; NM_006189.1.
DR   UniGene; Hs.673853; -.
DR   ProteinModelPortal; P47874; -.
DR   SMR; P47874; 1-163.
DR   DMDM; 1352639; -.
DR   PRIDE; P47874; -.
DR   GeneID; 4975; -.
DR   KEGG; hsa:4975; -.
DR   UCSC; uc001oxz.1; human.
DR   CTD; 4975; -.
DR   GeneCards; GC11P076813; -.
DR   H-InvDB; HIX0201743; -.
DR   HGNC; HGNC:8136; OMP.
DR   MIM; 164340; gene.
DR   neXtProt; NX_P47874; -.
DR   PharmGKB; PA31923; -.
DR   HOVERGEN; HBG007595; -.
DR   PhylomeDB; P47874; -.
DR   NextBio; 19150; -.
DR   Bgee; P47874; -.
DR   CleanEx; HS_OMP; -.
DR   Genevestigator; P47874; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0007608; P:sensory perception of smell; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   InterPro; IPR009103; Olfactory_marker.
DR   Gene3D; G3DSA:2.60.120.390; Olfactory_marker; 1.
DR   PANTHER; PTHR15357; Olfactory_marker; 1.
DR   Pfam; PF06554; Olfactory_mark; 1.
DR   ProDom; PD022055; Olfactory_marker; 1.
DR   SUPFAM; SSF63697; Olfactory_marker; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Complete proteome; Cytoplasm; Olfaction; Polymorphism;
KW   Reference proteome; Sensory transduction.
FT   INIT_MET      1      1       Removed (By similarity).
FT   CHAIN         2    163       Olfactory marker protein.
FT                                /FTId=PRO_0000058043.
FT   MOD_RES       2      2       N-acetylalanine (By similarity).
FT   VARIANT      26     26       R -> W (in dbSNP:rs2233546).
FT                                /FTId=VAR_051254.
FT   VARIANT      36     36       G -> R (in dbSNP:rs2233548).
FT                                /FTId=VAR_051255.
SQ   SEQUENCE   163 AA;  18937 MW;  EECD8AD16E7A328E CRC64;
     MAEDRPQQPQ LDMPLVLDQG LTRQMRLRVE SLKQRGEKRQ DGEKLLQPAE SVYRLNFTQQ
     QRLQFERWNV VLDKPGKVTI TGTSQNWTPD LTNLMTRQLL DPTAIFWRKE DSDAIDWNEA
     DALEFGERLS DLAKIRKVMY FLVTFGEGVE PANLKASVVF NQL
//