Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

40S ribosomal protein S4

Gene

RPS4

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-GGA-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-GGA-6791226. Major pathway of rRNA processing in the nucleolus.
R-GGA-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-GGA-72702. Ribosomal scanning and start codon recognition.
R-GGA-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-GGA-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-GGA-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S4
Gene namesi
Name:RPS4
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 26326240S ribosomal protein S4PRO_0000130823Add
BLAST

Proteomic databases

PaxDbiP47836.
PRIDEiP47836.

Expressioni

Gene expression databases

BgeeiENSGALG00000004831.
ExpressionAtlasiP47836. baseline.

Interactioni

Protein-protein interaction databases

BioGridi676272. 1 interaction.
STRINGi9031.ENSGALP00000039655.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini42 – 10463S4 RNA-bindingAdd
BLAST

Sequence similaritiesi

Belongs to the ribosomal protein S4e family.Curated
Contains 1 S4 RNA-binding domain.Curated

Phylogenomic databases

eggNOGiKOG0378. Eukaryota.
COG1471. LUCA.
HOGENOMiHOG000231325.
HOVERGENiHBG000935.
InParanoidiP47836.
KOiK02987.
OrthoDBiEOG091G0MYF.
PhylomeDBiP47836.

Family and domain databases

HAMAPiMF_00485. Ribosomal_S4e. 1 hit.
InterProiIPR032277. 40S_S4_C.
IPR005824. KOW.
IPR000876. Ribosomal_S4e.
IPR013845. Ribosomal_S4e_central_region.
IPR013843. Ribosomal_S4e_N.
IPR018199. Ribosomal_S4e_N_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERiPTHR11581. PTHR11581. 1 hit.
PfamiPF16121. 40S_S4_C. 1 hit.
PF00467. KOW. 1 hit.
PF00900. Ribosomal_S4e. 1 hit.
PF08071. RS4NT. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
PIRSFiPIRSF002116. Ribosomal_S4. 1 hit.
ProDomiPD002667. Ribosomal_S4e_central. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
PROSITEiPS00528. RIBOSOMAL_S4E. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P47836-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN
60 70 80 90 100
RLKYALTGDE VKKICMQRFI KIDGKVRTDI TYPAGFMDVI SIEKTGEHFR
110 120 130 140 150
LVYDTKGRFA VHRITAEEAK YKLCKVRKIF VGTKGIPHLV THDARTIRYP
160 170 180 190 200
DPLIKVNDTI QIDLETGKIT DFIKFDTGNL CMVTGGANLG RIGVITNRER
210 220 230 240 250
HPGSFDVVHV KDANGNSFAT RLSNIFVIGK GNKPWISLPR GKGIRLTIAE
260
ERDKRLAAKQ SSG
Length:263
Mass (Da):29,595
Last modified:January 23, 2007 - v2
Checksum:i4EE0B92F946BF202
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L24368 mRNA. Translation: AAB59946.1.
PIRiA56537.
RefSeqiNP_990439.1. NM_205108.1.
UniGeneiGga.4045.

Genome annotation databases

GeneIDi396001.
KEGGigga:396001.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L24368 mRNA. Translation: AAB59946.1.
PIRiA56537.
RefSeqiNP_990439.1. NM_205108.1.
UniGeneiGga.4045.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi676272. 1 interaction.
STRINGi9031.ENSGALP00000039655.

Proteomic databases

PaxDbiP47836.
PRIDEiP47836.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi396001.
KEGGigga:396001.

Organism-specific databases

CTDi6191.

Phylogenomic databases

eggNOGiKOG0378. Eukaryota.
COG1471. LUCA.
HOGENOMiHOG000231325.
HOVERGENiHBG000935.
InParanoidiP47836.
KOiK02987.
OrthoDBiEOG091G0MYF.
PhylomeDBiP47836.

Enzyme and pathway databases

ReactomeiR-GGA-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-GGA-6791226. Major pathway of rRNA processing in the nucleolus.
R-GGA-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-GGA-72702. Ribosomal scanning and start codon recognition.
R-GGA-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-GGA-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-GGA-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiP47836.

Gene expression databases

BgeeiENSGALG00000004831.
ExpressionAtlasiP47836. baseline.

Family and domain databases

HAMAPiMF_00485. Ribosomal_S4e. 1 hit.
InterProiIPR032277. 40S_S4_C.
IPR005824. KOW.
IPR000876. Ribosomal_S4e.
IPR013845. Ribosomal_S4e_central_region.
IPR013843. Ribosomal_S4e_N.
IPR018199. Ribosomal_S4e_N_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERiPTHR11581. PTHR11581. 1 hit.
PfamiPF16121. 40S_S4_C. 1 hit.
PF00467. KOW. 1 hit.
PF00900. Ribosomal_S4e. 1 hit.
PF08071. RS4NT. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
PIRSFiPIRSF002116. Ribosomal_S4. 1 hit.
ProDomiPD002667. Ribosomal_S4e_central. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
PROSITEiPS00528. RIBOSOMAL_S4E. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRS4_CHICK
AccessioniPrimary (citable) accession number: P47836
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 98 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.