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Protein

40S ribosomal protein S4

Gene

RPS4

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-GGA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-GGA-72649 Translation initiation complex formation
R-GGA-72689 Formation of a pool of free 40S subunits
R-GGA-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-GGA-72702 Ribosomal scanning and start codon recognition
R-GGA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-GGA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-GGA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S4
Gene namesi
Name:RPS4
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001308232 – 26340S ribosomal protein S4Add BLAST262

Proteomic databases

PaxDbiP47836
PRIDEiP47836

Expressioni

Gene expression databases

BgeeiENSGALG00000004831
ExpressionAtlasiP47836 baseline

Interactioni

Protein-protein interaction databases

BioGridi676272, 1 interactor
STRINGi9031.ENSGALP00000039655

Structurei

3D structure databases

SMRiP47836
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 104S4 RNA-bindingAdd BLAST63

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0378 Eukaryota
COG1471 LUCA
GeneTreeiENSGT00390000005569
HOGENOMiHOG000231325
HOVERGENiHBG000935
InParanoidiP47836
KOiK02987
OrthoDBiEOG091G0MYF
PhylomeDBiP47836

Family and domain databases

CDDicd00165 S4, 1 hit
Gene3Di2.30.30.30, 1 hit
2.40.50.740, 1 hit
HAMAPiMF_00485 Ribosomal_S4e, 1 hit
InterProiView protein in InterPro
IPR032277 40S_S4_C
IPR005824 KOW
IPR014722 Rib_L2_dom2
IPR000876 Ribosomal_S4e
IPR013845 Ribosomal_S4e_central_region
IPR038237 Ribosomal_S4e_central_sf
IPR013843 Ribosomal_S4e_N
IPR018199 Ribosomal_S4e_N_CS
IPR002942 S4_RNA-bd
PANTHERiPTHR11581 PTHR11581, 1 hit
PfamiView protein in Pfam
PF16121 40S_S4_C, 1 hit
PF00467 KOW, 1 hit
PF00900 Ribosomal_S4e, 1 hit
PF08071 RS4NT, 1 hit
PF01479 S4, 1 hit
PIRSFiPIRSF002116 Ribosomal_S4, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002667 Ribosomal_S4e_central, 1 hit
SMARTiView protein in SMART
SM00363 S4, 1 hit
PROSITEiView protein in PROSITE
PS00528 RIBOSOMAL_S4E, 1 hit
PS50889 S4, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P47836-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN
60 70 80 90 100
RLKYALTGDE VKKICMQRFI KIDGKVRTDI TYPAGFMDVI SIEKTGEHFR
110 120 130 140 150
LVYDTKGRFA VHRITAEEAK YKLCKVRKIF VGTKGIPHLV THDARTIRYP
160 170 180 190 200
DPLIKVNDTI QIDLETGKIT DFIKFDTGNL CMVTGGANLG RIGVITNRER
210 220 230 240 250
HPGSFDVVHV KDANGNSFAT RLSNIFVIGK GNKPWISLPR GKGIRLTIAE
260
ERDKRLAAKQ SSG
Length:263
Mass (Da):29,595
Last modified:January 23, 2007 - v2
Checksum:i4EE0B92F946BF202
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L24368 mRNA Translation: AAB59946.1
PIRiA56537
RefSeqiNP_990439.1, NM_205108.1
UniGeneiGga.4045

Genome annotation databases

EnsembliENSGALT00000067049; ENSGALP00000052806; ENSGALG00000004831
GeneIDi396001
KEGGigga:396001

Similar proteinsi

Entry informationi

Entry nameiRS4_CHICK
AccessioniPrimary (citable) accession number: P47836
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 111 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health