Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphomannomutase

Gene

manB

Organism
Mycoplasma pirum
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.

Cofactori

Mg2+By similarityNote: Binds 1 Mg2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei145 – 1451Phosphoserine intermediateBy similarity
Metal bindingi145 – 1451Magnesium; via phosphate groupBy similarity
Metal bindingi297 – 2971MagnesiumBy similarity
Metal bindingi299 – 2991MagnesiumBy similarity
Metal bindingi301 – 3011MagnesiumBy similarity

GO - Molecular functioni

  1. magnesium ion binding Source: InterPro
  2. phosphomannomutase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Ligandi

Magnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphomannomutase (EC:5.4.2.8)
Short name:
PMM
Gene namesi
Name:manB
Synonyms:cpsG
OrganismiMycoplasma pirum
Taxonomic identifieri2122 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 544544PhosphomannomutasePRO_0000147829Add
BLAST

Keywords - PTMi

Phosphoprotein

Structurei

3D structure databases

ProteinModelPortaliP47723.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphohexose mutase family.Curated

Family and domain databases

Gene3Di3.30.310.50. 1 hit.
3.40.120.10. 3 hits.
InterProiIPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016066. A-D-PHexomutase_CS.
[Graphical view]
PfamiPF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
[Graphical view]
SUPFAMiSSF53738. SSF53738. 3 hits.
SSF55957. SSF55957. 1 hit.
PROSITEiPS00710. PGM_PMM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47723-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNNEIVKKWL SSDNVPQTDK DIISKMKNEE LELAFSNAPL SFGTAGIRAK
60 70 80 90 100
MAPGTQFLNK ITYYQMATGY GKFLKNKFSN QNISVIVAHD NRNNGIDFSI
110 120 130 140 150
DVTNILTSLE LEFICLKIIN LLLRQLFSYA IRKLNAQGAV IVTASHNPKE
160 170 180 190 200
DNGFKIYNET GAQVLPDDGL KVVELMPNVF EMIDLKVAND DSLITYLNED
210 220 230 240 250
IFRQYYEDCK QALIKTNINE SKEFSIVFSG QHGTACKRLP EFLKLLGYKN
260 270 280 290 300
IILVEEQCIF DGNFSNTPTP NPENRAAWDL SIEYADKNNA NVIIQVDPDA
310 320 330 340 350
DRFALGVRYK NSWRFLSGNQ MGIIYTDYIL KNKTFTKKPY IVSSYVSTNL
360 370 380 390 400
IDRIIKEYHG EVYRVGTGFK WVGDKINKIK DSEEFVVGFE EAVGALNSTI
410 420 430 440 450
NRDKDAYQAA ALALEIYNEC LKNNINIIDH LEKNIYGKYG IIHNDTISFT
460 470 480 490 500
FVENNWKELV KKSLDKILKY SEKTIGNRTI TSIKYNEVGG CYDWILDGDS
510 520 530 540
WLRFRMSGTE PKFKVYYNLY GENLNALSQE AKTINDQIKT LLNL
Length:544
Mass (Da):62,109
Last modified:February 1, 1996 - v1
Checksum:iC4F8201F6D7887D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L13289 Genomic DNA. Translation: AAA25434.1.
PIRiE53312.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L13289 Genomic DNA. Translation: AAA25434.1.
PIRiE53312.

3D structure databases

ProteinModelPortaliP47723.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.30.310.50. 1 hit.
3.40.120.10. 3 hits.
InterProiIPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016066. A-D-PHexomutase_CS.
[Graphical view]
PfamiPF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
[Graphical view]
SUPFAMiSSF53738. SSF53738. 3 hits.
SSF55957. SSF55957. 1 hit.
PROSITEiPS00710. PGM_PMM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Identification of Mycoplasma pirum genes involved in the salvage pathways for nucleosides."
    Tham T.N., Ferris S., Kovacic R., Montagnier L., Blanchard A.
    J. Bacteriol. 175:5281-5285(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: BER.

Entry informationi

Entry nameiMANB_MYCPI
AccessioniPrimary (citable) accession number: P47723
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: November 26, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.