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P47722 (DEOC_MYCPI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Deoxyribose-phosphate aldolase

Short name=DERA
EC=4.1.2.4
Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase
Phosphodeoxyriboaldolase
Short name=Deoxyriboaldolase
Gene names
Name:deoC
OrganismMycoplasma pirum
Taxonomic identifier2122 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length220 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP-Rule MF_00114

Catalytic activity

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP-Rule MF_00114

Pathway

Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP-Rule MF_00114

Subcellular location

Cytoplasm HAMAP-Rule MF_00114.

Sequence similarities

Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandSchiff base
   Molecular functionLyase
Gene Ontology (GO)
   Biological_processcarbohydrate catabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

deoxyribonucleotide catabolic process

Inferred from electronic annotation. Source: InterPro

deoxyribose phosphate catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiondeoxyribose-phosphate aldolase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 220220Deoxyribose-phosphate aldolase HAMAP-Rule MF_00114
PRO_0000057244

Sites

Active site1501Schiff-base intermediate with acetaldehyde By similarity
Active site1821 By similarity

Sequences

Sequence LengthMass (Da)Tools
P47722 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: E3BB251D8AAA8C78

FASTA22024,421
        10         20         30         40         50         60 
MNYNSLFDHT LLRADASVEE IKQLCDEAVK FNFFSVCVNP SYVPYVKEQL HNSSVKICTV 

        70         80         90        100        110        120 
VGFPLGQTST KQKVYETKIA IKEGADEIDM VLNISEFKEN CACVVNEIRK YKKVCKKKIL 

       130        140        150        160        170        180 
KVIVETALLS ENEIEKATLV VIDGGADFIK TSTGFSSRGA SIKDIEIMKN VIEKNNSKLK 

       190        200        210        220 
IKASGGIKTL TFVEELIKAG AERIGSSKSV EIIKETLNKN 

« Hide

References

[1]"Identification of Mycoplasma pirum genes involved in the salvage pathways for nucleosides."
Tham T.N., Ferris S., Kovacic R., Montagnier L., Blanchard A.
J. Bacteriol. 175:5281-5285(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: BER.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L13289 Genomic DNA. Translation: AAA25431.1.
PIRB53312.

3D structure databases

ProteinModelPortalP47722.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00002; UER00468.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00114. DeoC_type1.
InterProIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/FbaB/lacD_aldolase.
IPR028581. DeoC_typeI.
[Graphical view]
PANTHERPTHR10889. PTHR10889. 1 hit.
PfamPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFPIRSF001357. DeoC. 1 hit.
TIGRFAMsTIGR00126. deoC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDEOC_MYCPI
AccessionPrimary (citable) accession number: P47722
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: February 19, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways