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Protein

Deoxyribose-phosphate aldolase

Gene

deoC

Organism
Mycoplasma pirum
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.UniRule annotation

Catalytic activityi

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.UniRule annotation

Pathwayi: 2-deoxy-D-ribose 1-phosphate degradation

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Deoxyribose-phosphate aldolase (deoC)
This subpathway is part of the pathway 2-deoxy-D-ribose 1-phosphate degradation, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate, the pathway 2-deoxy-D-ribose 1-phosphate degradation and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei89Proton donor/acceptorUniRule annotation1
Active sitei150Schiff-base intermediate with acetaldehydeUniRule annotation1
Active sitei182Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
LigandSchiff base

Enzyme and pathway databases

UniPathwayiUPA00002; UER00468

Names & Taxonomyi

Protein namesi
Recommended name:
Deoxyribose-phosphate aldolaseUniRule annotation (EC:4.1.2.4UniRule annotation)
Short name:
DERAUniRule annotation
Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolaseUniRule annotation
PhosphodeoxyriboaldolaseUniRule annotation
Short name:
DeoxyriboaldolaseUniRule annotation
Gene namesi
Name:deoCUniRule annotation
OrganismiMycoplasma pirum
Taxonomic identifieri2122 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000572441 – 220Deoxyribose-phosphate aldolaseAdd BLAST220

Structurei

3D structure databases

ProteinModelPortaliP47722
SMRiP47722
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.UniRule annotationCurated

Family and domain databases

CDDicd00959 DeoC, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_00114 DeoC_type1, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR011343 DeoC
IPR002915 DeoC/FbaB/lacD_aldolase
IPR028581 DeoC_typeI
PANTHERiPTHR10889 PTHR10889, 1 hit
PTHR10889:SF1 PTHR10889:SF1, 1 hit
PfamiView protein in Pfam
PF01791 DeoC, 1 hit
PIRSFiPIRSF001357 DeoC, 1 hit
SMARTiView protein in SMART
SM01133 DeoC, 1 hit
TIGRFAMsiTIGR00126 deoC, 1 hit

Sequencei

Sequence statusi: Complete.

P47722-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNYNSLFDHT LLRADASVEE IKQLCDEAVK FNFFSVCVNP SYVPYVKEQL
60 70 80 90 100
HNSSVKICTV VGFPLGQTST KQKVYETKIA IKEGADEIDM VLNISEFKEN
110 120 130 140 150
CACVVNEIRK YKKVCKKKIL KVIVETALLS ENEIEKATLV VIDGGADFIK
160 170 180 190 200
TSTGFSSRGA SIKDIEIMKN VIEKNNSKLK IKASGGIKTL TFVEELIKAG
210 220
AERIGSSKSV EIIKETLNKN
Length:220
Mass (Da):24,421
Last modified:February 1, 1996 - v1
Checksum:iE3BB251D8AAA8C78
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L13289 Genomic DNA Translation: AAA25431.1
PIRiB53312

Similar proteinsi

Entry informationi

Entry nameiDEOC_MYCPI
AccessioniPrimary (citable) accession number: P47722
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: May 23, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

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