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P47718

- CDD_MYCPI

UniProt

P47718 - CDD_MYCPI

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Protein
Cytidine deaminase
Gene
cdd
Organism
Mycoplasma pirum
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis By similarity.

Catalytic activityi

Cytidine + H2O = uridine + NH3.
2'deoxycytidine + H2O = 2'-deoxyuridine + NH3.

Cofactori

Binds 1 zinc ion By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi53 – 531Zinc; catalytic By similarity
Active sitei55 – 551Proton donor By similarity
Metal bindingi88 – 881Zinc; catalytic By similarity
Metal bindingi91 – 911Zinc; catalytic By similarity

GO - Molecular functioni

  1. cytidine deaminase activity Source: UniProtKB-EC
  2. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Cytidine deaminase (EC:3.5.4.5)
Short name:
CDA
Alternative name(s):
Cytidine aminohydrolase
Gene namesi
Name:cdd
OrganismiMycoplasma pirum
Taxonomic identifieri2122 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 133133Cytidine deaminase
PRO_0000171680Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.

Structurei

3D structure databases

ProteinModelPortaliP47718.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 103103CMP/dCMP deaminase zinc-binding
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni42 – 443Substrate binding By similarity

Sequence similaritiesi

Family and domain databases

InterProiIPR016192. APOBEC/CMP_deaminase_Zn-bd.
IPR002125. CMP_dCMP_Zn-bd.
IPR006262. Cyt_deam_tetra.
IPR016193. Cytidine_deaminase-like.
[Graphical view]
PfamiPF00383. dCMP_cyt_deam_1. 1 hit.
[Graphical view]
SUPFAMiSSF53927. SSF53927. 1 hit.
TIGRFAMsiTIGR01354. cyt_deam_tetra. 1 hit.
PROSITEiPS00903. CYT_DCMP_DEAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47718-1 [UniParc]FASTAAdd to Basket

« Hide

MKEKDIYFQK LNELISNAYV PYSNFRVSCL LLTDGGWFAG VNIENSAYSP    50
TICAERSAVS SMITSGFKQI FKVYILTDTI VKDIGTPCGV CRQVLSEFAK 100
PETPIITYNL KGEKFFYTLE QLLPFAFNKD ALK 133
Length:133
Mass (Da):15,018
Last modified:February 1, 1996 - v1
Checksum:i19CB3314EEAF12C4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L13289 Genomic DNA. Translation: AAA25433.1.
PIRiD53312.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L13289 Genomic DNA. Translation: AAA25433.1 .
PIRi D53312.

3D structure databases

ProteinModelPortali P47718.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR016192. APOBEC/CMP_deaminase_Zn-bd.
IPR002125. CMP_dCMP_Zn-bd.
IPR006262. Cyt_deam_tetra.
IPR016193. Cytidine_deaminase-like.
[Graphical view ]
Pfami PF00383. dCMP_cyt_deam_1. 1 hit.
[Graphical view ]
SUPFAMi SSF53927. SSF53927. 1 hit.
TIGRFAMsi TIGR01354. cyt_deam_tetra. 1 hit.
PROSITEi PS00903. CYT_DCMP_DEAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Identification of Mycoplasma pirum genes involved in the salvage pathways for nucleosides."
    Tham T.N., Ferris S., Kovacic R., Montagnier L., Blanchard A.
    J. Bacteriol. 175:5281-5285(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: BER.

Entry informationi

Entry nameiCDD_MYCPI
AccessioniPrimary (citable) accession number: P47718
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: May 14, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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