P47691 (GALU_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UTP--glucose-1-phosphate uridylyltransferase
EC=2.7.7.9

Alternative name(s):
Alpha-D-glucosyl-1-phosphate uridylyltransferase
UDP-glucose pyrophosphorylase
Short name=UDPGP
Uridine diphosphoglucose pyrophosphorylase

Gene names

Name:	galU
Synonyms:	gtaB
Ordered Locus Names:	MG453

Organism

Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]

Taxonomic identifier

243273 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Tenericutes › Mollicutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma genitalium

Protein attributes

Sequence length	292 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May play a role in stationary phase survival By similarity.
Catalytic activity	UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.
Sequence similarities	Belongs to the UDPGP type 2 family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	UDP-glucose metabolic process Inferred from electronic annotation. Source: InterPro biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	UTP:glucose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 292	292	UTP--glucose-1-phosphate uridylyltransferase		PRO_0000201359

Sequences

	Sequence		Length	Mass (Da)
	P47691 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: 27EB08EC8147E93A	FASTA	292	32,514
	10 20 30 40 50 60 MKTKIRKAVI PAAGLGVRLL PATKAIPKEM LPLVNKPTIQ YIVEEAVKSG IEQILVIVSS 70 80 90 100 110 120 KKTAILDHFD YDLILENALI QKNKLQEHKE IEDIANLAHI FFVRQKNQDG LGDAILFAES 130 140 150 160 170 180 FVGNEDFAVL LGDDVVFSKE PALKQCLEAY YETNCQTIGV QEVDPCHVDK YGIITPEGDY 190 200 210 220 230 240 KNKDLIKVLA MTEKPKPKDA KSNLAILGRY VLKPSIFKAL RSVPYGVGGE LQLTDGLNFC 250 260 270 280 290 LKNENFYARK FTGTRFDVGT KSGFIKANLF TALNNKDISK KEVLELLNLV KA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. , Phillips C.A., Merrick J.M., Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C. Science 270:397-403(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195.
[2]	"A survey of the Mycoplasma genitalium genome by using random sequencing." Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 61-163. Strain: ATCC 33530 / G-37 / NCTC 10195.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L43967 Genomic DNA. Translation: AAC72473.1. U02258 Genomic DNA. Translation: AAD12523.1.
PIR	A64250.
RefSeq	NP_073123.1. NC_000908.2.
3D structure databases
ProteinModelPortal	P47691.
ModBase	Search...
Protein-protein interaction databases
STRING	243273.MG_453.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC72473; AAC72473; MG_453.
GeneID	875603.
KEGG	mge:MG_453.
PATRIC	20010496. VBIMycGen98045_0521.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1210.
KO	K00963.
OMA	ISEKPCL.
ProtClustDB	CLSK335352.
Enzyme and pathway databases
BioCyc	MGEN243273:GH2R-504-MONOMER.
Family and domain databases
InterPro	IPR005771. GalU_uridylyltTrfase_bac/arc. IPR005835. NTP_transferase. [Graphical view]
Pfam	PF00483. NTP_transferase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01099. galU. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GALU_MYCGE

Accession

Primary (citable) accession number: P47691

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	May 1, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program