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P47669

- GPMI_MYCGE

UniProt

P47669 - GPMI_MYCGE

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Protein

2,3-bisphosphoglycerate-independent phosphoglycerate mutase

Gene

gpmI

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.By similarity

Catalytic activityi

2-phospho-D-glycerate = 3-phospho-D-glycerate.

Cofactori

Mn2+By similarityNote: Binds 2 manganese ions per subunit.By similarity

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi11 – 111Manganese 2By similarity
Active sitei61 – 611Phosphoserine intermediateBy similarity
Metal bindingi61 – 611Manganese 2By similarity
Metal bindingi397 – 3971Manganese 1By similarity
Metal bindingi401 – 4011Manganese 1By similarity
Metal bindingi438 – 4381Manganese 2By similarity
Metal bindingi439 – 4391Manganese 2By similarity
Metal bindingi456 – 4561Manganese 1By similarity

GO - Molecular functioni

  1. 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Source: UniProtKB-HAMAP
  2. manganese ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. glucose catabolic process Source: InterPro
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

Manganese, Metal-binding

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-484-MONOMER.
UniPathwayiUPA00109; UER00186.

Names & Taxonomyi

Protein namesi
Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC:5.4.2.12)
Short name:
BPG-independent PGAM
Short name:
Phosphoglyceromutase
Short name:
iPGM
Gene namesi
Name:gpmI
Synonyms:pgm
Ordered Locus Names:MG430
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 5075072,3-bisphosphoglycerate-independent phosphoglycerate mutasePRO_0000212167Add
BLAST

Proteomic databases

PRIDEiP47669.

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi243273.MG_430.

Structurei

3D structure databases

ProteinModelPortaliP47669.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0696.
KOiK15633.
OrthoDBiEOG6HJ22X.

Family and domain databases

Gene3Di3.40.1450.10. 1 hit.
3.40.720.10. 2 hits.
HAMAPiMF_01038. GpmI.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR011258. BPG-indep_PGM_N.
IPR006124. Metalloenzyme.
IPR005995. Pgm_bpd_ind.
[Graphical view]
PfamiPF06415. iPGM_N. 1 hit.
PF01676. Metalloenzyme. 1 hit.
[Graphical view]
PIRSFiPIRSF001492. IPGAM. 1 hit.
SUPFAMiSSF53649. SSF53649. 2 hits.
SSF64158. SSF64158. 1 hit.
TIGRFAMsiTIGR01307. pgm_bpd_ind. 1 hit.

Sequencei

Sequence statusi: Complete.

P47669-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MHKKVLLAIL DGYGISNAIY GNAVQNANTP MLDELINSYP CVLLDASGEA
60 70 80 90 100
VGLPMGQIGN SEVGHLNIGA GRVVYTGLSL INQHIKDRSF FANKAFLKTI
110 120 130 140 150
EHVEKNHSKI HLIGLFSNGG VHSHNEHLLA LIELFSKHAK VVLHLFGDGR
160 170 180 190 200
DVAPCSLKQD LEKLMIFLKN YPNVVIGTIG GRYYGMDRDQ RWDREMIAYK
210 220 230 240 250
ALLGVSKNKF NDPIGYIETQ YQNQITDEFI YPAINANLNS DQFALNNNDG
260 270 280 290 300
VISFNFRPDR ARQMSHLIFN SNYYNYQPEL KRKENLFFVT MMNYEGIVPS
310 320 330 340 350
EFAFPPQTIK NSLGEVIANN NLKQLRIAET EKYAHVTFFF DGGFEVNLSN
360 370 380 390 400
ETKTLIPSLK VATYDLAPEM SCKAITDALL EKLNNFDFTV LNFANPDMVG
410 420 430 440 450
HTGNYQACIK ALEALDVQIK RIVDFCKANQ ITMFLTADHG NAEVMIDNNN
460 470 480 490 500
NPVTKHTINP VPFVCTDKNV NFNQTGILAN IAPTILEYLN LSKPKEMTAK

SLLKNNN
Length:507
Mass (Da):56,867
Last modified:October 1, 1996 - v1
Checksum:i9BD9F5007C9CBEB5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC72451.1.
PIRiE64247.
RefSeqiNP_073101.2. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC72451; AAC72451; MG_430.
GeneIDi875625.
KEGGimge:MG_430.
PATRICi20010446. VBIMycGen98045_0496.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC72451.1 .
PIRi E64247.
RefSeqi NP_073101.2. NC_000908.2.

3D structure databases

ProteinModelPortali P47669.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243273.MG_430.

Proteomic databases

PRIDEi P47669.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC72451 ; AAC72451 ; MG_430 .
GeneIDi 875625.
KEGGi mge:MG_430.
PATRICi 20010446. VBIMycGen98045_0496.

Phylogenomic databases

eggNOGi COG0696.
KOi K15633.
OrthoDBi EOG6HJ22X.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00186 .
BioCyci MGEN243273:GH2R-484-MONOMER.

Family and domain databases

Gene3Di 3.40.1450.10. 1 hit.
3.40.720.10. 2 hits.
HAMAPi MF_01038. GpmI.
InterProi IPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR011258. BPG-indep_PGM_N.
IPR006124. Metalloenzyme.
IPR005995. Pgm_bpd_ind.
[Graphical view ]
Pfami PF06415. iPGM_N. 1 hit.
PF01676. Metalloenzyme. 1 hit.
[Graphical view ]
PIRSFi PIRSF001492. IPGAM. 1 hit.
SUPFAMi SSF53649. SSF53649. 2 hits.
SSF64158. SSF64158. 1 hit.
TIGRFAMsi TIGR01307. pgm_bpd_ind. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiGPMI_MYCGE
AccessioniPrimary (citable) accession number: P47669
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 26, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3