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Protein

ATP synthase subunit b

Gene

atpF

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

F1F0 ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F1 containing the extramembraneous catalytic core and F0 containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation.UniRule annotation
Component of the F0 channel, it forms part of the peripheral stalk, linking F1 to F0.UniRule annotation

GO - Molecular functioni

  1. proton-transporting ATP synthase activity, rotational mechanism Source: UniProtKB-HAMAP

GO - Biological processi

  1. plasma membrane ATP synthesis coupled proton transport Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

ATP synthesis, Hydrogen ion transport, Ion transport, Transport

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-460-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit bUniRule annotation
Alternative name(s):
ATP synthase F(0) sector subunit bUniRule annotation
ATPase subunit IUniRule annotation
F-type ATPase subunit bUniRule annotation
Short name:
F-ATPase subunit bUniRule annotation
Gene namesi
Name:atpFUniRule annotation
Ordered Locus Names:MG403
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

Subcellular locationi

Cell membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei49 – 6921HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
  3. proton-transporting ATP synthase complex, coupling factor F(o) Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, CF(0), Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727By similarityAdd
BLAST
Chaini28 – 208181ATP synthase subunit bPRO_0000002631Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi28 – 281N-palmitoyl cysteineBy similarity
Lipidationi28 – 281S-diacylglycerol cysteineBy similarity

Keywords - PTMi

Lipoprotein, Palmitate

Interactioni

Subunit structurei

F-type ATPases have 2 components, F1 - the catalytic core - and F0 - the membrane proton channel. F1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. F0 has three main subunits: a1, b2 and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F1 is attached to F0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.UniRule annotation

Protein-protein interaction databases

STRINGi243273.MG_403.

Structurei

3D structure databases

ProteinModelPortaliP47643.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase B chain family.UniRule annotation

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0711.
KOiK02109.
OMAiSINQKTH.
OrthoDBiEOG63VC12.

Family and domain databases

HAMAPiMF_01398. ATP_synth_b_bact.
InterProiIPR028987. ATPase_B-like_membr.
IPR002146. ATPase_F0-cplx_b/b'su_bac.
IPR005864. ATPase_F0-cplx_bsu_bac.
[Graphical view]
PfamiPF00430. ATP-synt_B. 1 hit.
[Graphical view]
SUPFAMiSSF81573. SSF81573. 1 hit.
TIGRFAMsiTIGR01144. ATP_synt_b. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P47643-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKAKKLVFK WSLLVFSFFT LSLFLVSCTE NVREIKSSSV INELFPNFWV
60 70 80 90 100
FITHLLAFFI LLTLMIFLFW KPTQRFLNNR KNLLEAQIKQ ANELEKQARN
110 120 130 140 150
LLEESNQRHE KALIVSKEIV DQANYEALQL KSEIEKTANR QANLMIFQAR
160 170 180 190 200
QEIEKERRSL KEQSIKESVE LAMLAAQELI LKKIDQKSDR EFIDKFIRDL

EANETEDD
Length:208
Mass (Da):24,603
Last modified:February 1, 1996 - v1
Checksum:i0AB6526A367F84E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71631.1.
PIRiF64244.
RefSeqiNP_073076.1. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC71631; AAC71631; MG_403.
GeneIDi875648.
KEGGimge:MG_403.
PATRICi20010394. VBIMycGen98045_0470.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71631.1.
PIRiF64244.
RefSeqiNP_073076.1. NC_000908.2.

3D structure databases

ProteinModelPortaliP47643.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243273.MG_403.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC71631; AAC71631; MG_403.
GeneIDi875648.
KEGGimge:MG_403.
PATRICi20010394. VBIMycGen98045_0470.

Phylogenomic databases

eggNOGiCOG0711.
KOiK02109.
OMAiSINQKTH.
OrthoDBiEOG63VC12.

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-460-MONOMER.

Family and domain databases

HAMAPiMF_01398. ATP_synth_b_bact.
InterProiIPR028987. ATPase_B-like_membr.
IPR002146. ATPase_F0-cplx_b/b'su_bac.
IPR005864. ATPase_F0-cplx_bsu_bac.
[Graphical view]
PfamiPF00430. ATP-synt_B. 1 hit.
[Graphical view]
SUPFAMiSSF81573. SSF81573. 1 hit.
TIGRFAMsiTIGR01144. ATP_synt_b. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiATPF_MYCGE
AccessioniPrimary (citable) accession number: P47643
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: January 7, 2015
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.