ATP synthase subunit beta - Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)

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P47639 (ATPB_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 100. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
ATP synthase subunit beta
EC=3.6.3.14

Alternative name(s):
ATP synthase F1 sector subunit beta
F-ATPase subunit beta

Gene names

Name:	atpD
Ordered Locus Names:	MG399

Organism

Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]

Taxonomic identifier

243273 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma ›

Protein attributes

Sequence length	476 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits By similarity. HAMAP-Rule MF_01347
Catalytic activity	ATP + H₂O + H⁺(In) = ADP + phosphate + H⁺(Out). HAMAP-Rule MF_01347
Subunit structure	F-type ATPases have 2 components, CF₁ - the catalytic core - and CF₀ - the membrane proton channel. CF₁ has five subunits: alpha₃, beta₃, gamma₁, delta₁, epsilon₁. CF₀ has three main subunits: a₁, b₂ and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF₁ is attached to CF₀ by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.
Subcellular location	Cell membrane; Peripheral membrane protein By similarity HAMAP-Rule MF_01347.
Sequence similarities	Belongs to the ATPase alpha/beta chains family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(1) Cell membrane Membrane
Ligand	ATP-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ATP hydrolysis coupled proton transport Inferred from electronic annotation. Source: InterPro plasma membrane ATP synthesis coupled proton transport Inferred from electronic annotation. Source: HAMAP
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell proton-transporting ATP synthase complex, catalytic core F(1) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP proton-transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 476

476

ATP synthase subunit beta HAMAP-Rule MF_01347

PRO_0000144451

Regions

Nucleotide binding

157 – 164

ATP By similarity

Sequences

Sequence

Length

Mass (Da)

Tools

P47639 [UniParc].

Last modified November 1, 1997. Version 2.
Checksum: 00E69866B188CE42
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FASTA

476

52,549

        10         20         30         40         50         60 
MIKKENLTYG KVHQVIGPVV DVIFSESKQL PRVYDCLSVQ LKKSELFLEA TQLIGDDIVR 

        70         80         90        100        110        120 
CIALGPTEGL ARNVKVTNYN HPIEVPVGKN VLGRMFNVLG EPIDGKEPLP KKPKLSIHRN 

       130        140        150        160        170        180 
PPAFDEQPNT VDIFETGIKV IDLLTPYVRG GKIGLFGGAG VGKTVLVQEL IHNIAKEHSG 

       190        200        210        220        230        240 
LSVFAGVGER TREGNDLYYE MIQGGVIDKT VLVFGQMNEP PGARMRVALT ALTMAEYFRD 

       250        260        270        280        290        300 
HDNQNVLLFI DNIFRFTQAG SEVSALLGRM PSAVGYQPTL AIEMGKLQER IASTKTGSIT 

       310        320        330        340        350        360 
SVQAIYVPAD DLTDPAPATT FTHLDAKTVL DRNIAALGIF PAINPLESTS RLLDPSVVGI 

       370        380        390        400        410        420 
NHYKVALGVQ NILQRFAELQ DIIAILGIDE LSDEDKIIVE RARRIRNFLS QPFFVAEKFS 

       430        440        450        460        470 
GIAGKYVSLN DTVQSFKEIL EGKHDHLPEQ AFFYVGTIQE AVEKAKRLNQ EFDKTK

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. Venter J.C. Science 270:397-403(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195.
[2]	"A survey of the Mycoplasma genitalium genome by using random sequencing." Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 244-378. Strain: ATCC 33530 / G-37 / NCTC 10195.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L43967 Genomic DNA. Translation: AAC71627.1. U01752 Genomic DNA. Translation: AAD10566.1.
RefSeq	NP_073072.1. NC_000908.2.
3D structure databases
ProteinModelPortal	P47639.
SMR	P47639. Positions 10-468.
ModBase	Search...
Protein-protein interaction databases
STRING	243273.MG_399.
Proteomic databases
PRIDE	P47639.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC71627; AAC71627; MG_399.
GeneID	875652.
KEGG	mge:MG_399.
PATRIC	20010386. VBIMycGen98045_0466.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0055.
KO	K02112.
OMA	NNIAKGH.
ProtClustDB	PRK09280.
Enzyme and pathway databases
BioCyc	MGEN243273:GH2R-456-MONOMER.
Family and domain databases
Gene3D	1.10.1140.10. 1 hit.
HAMAP	MF_01347. ATP_synth_beta_bact.
InterPro	IPR003593. AAA+_ATPase. IPR020003. ATPase_a/bsu_AS. IPR004100. ATPase_a/bsu_N. IPR005722. ATPase_F1-cplx_bsu. IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C. IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd. IPR024034. ATPase_F1_bsu/V1_C. IPR027417. P-loop_NTPase. [Graphical view]
PANTHER	PTHR15184:SF8. PTHR15184:SF8. 1 hit.
Pfam	PF00006. ATP-synt_ab. 1 hit. PF00306. ATP-synt_ab_C. 1 hit. PF02874. ATP-synt_ab_N. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF47917. ATPase_a/b_C. 1 hit. SSF50615. ATPase_a/b_N. 1 hit. SSF52540. SSF52540. 1 hit.
TIGRFAMs	TIGR01039. atpD. 1 hit.
PROSITE	PS00152. ATPASE_ALPHA_BETA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATPB_MYCGE

Accession

Primary (citable) accession number: P47639

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	November 1, 1997
Last modified:	May 29, 2013
This is version 100 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

Mycoplasma genitalium

Mycoplasma genitalium (strain G-37): entries and gene names

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information

Relevant documents