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P47639 (ATPB_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 105. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
ATP synthase subunit beta

EC=3.6.3.14
Alternative name(s):
ATP synthase F1 sector subunit beta
F-ATPase subunit beta
Gene names
Name:atpD
Ordered Locus Names:MG399
OrganismMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]
Taxonomic identifier243273 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length476 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits By similarity. HAMAP-Rule MF_01347

Catalytic activity

ATP + H2O + H+(In) = ADP + phosphate + H+(Out). HAMAP-Rule MF_01347

Subunit structure

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.

Subcellular location

Cell membrane; Peripheral membrane protein By similarity HAMAP-Rule MF_01347.

Sequence similarities

Belongs to the ATPase alpha/beta chains family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 476476ATP synthase subunit beta HAMAP-Rule MF_01347
PRO_0000144451

Regions

Nucleotide binding157 – 1648ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P47639 [UniParc].

Last modified November 1, 1997. Version 2.
Checksum: 00E69866B188CE42

FASTA47652,549
        10         20         30         40         50         60 
MIKKENLTYG KVHQVIGPVV DVIFSESKQL PRVYDCLSVQ LKKSELFLEA TQLIGDDIVR 

        70         80         90        100        110        120 
CIALGPTEGL ARNVKVTNYN HPIEVPVGKN VLGRMFNVLG EPIDGKEPLP KKPKLSIHRN 

       130        140        150        160        170        180 
PPAFDEQPNT VDIFETGIKV IDLLTPYVRG GKIGLFGGAG VGKTVLVQEL IHNIAKEHSG 

       190        200        210        220        230        240 
LSVFAGVGER TREGNDLYYE MIQGGVIDKT VLVFGQMNEP PGARMRVALT ALTMAEYFRD 

       250        260        270        280        290        300 
HDNQNVLLFI DNIFRFTQAG SEVSALLGRM PSAVGYQPTL AIEMGKLQER IASTKTGSIT 

       310        320        330        340        350        360 
SVQAIYVPAD DLTDPAPATT FTHLDAKTVL DRNIAALGIF PAINPLESTS RLLDPSVVGI 

       370        380        390        400        410        420 
NHYKVALGVQ NILQRFAELQ DIIAILGIDE LSDEDKIIVE RARRIRNFLS QPFFVAEKFS 

       430        440        450        460        470 
GIAGKYVSLN DTVQSFKEIL EGKHDHLPEQ AFFYVGTIQE AVEKAKRLNQ EFDKTK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L43967 Genomic DNA. Translation: AAC71627.1.
U01752 Genomic DNA. Translation: AAD10566.1.
RefSeqNP_073072.1. NC_000908.2.

3D structure databases

ProteinModelPortalP47639.
SMRP47639. Positions 10-468.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243273.MG_399.

Proteomic databases

PRIDEP47639.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC71627; AAC71627; MG_399.
GeneID875652.
KEGGmge:MG_399.
PATRIC20010386. VBIMycGen98045_0466.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0055.
KOK02112.
OMAKYLSQPF.
OrthoDBEOG6HQSP3.

Enzyme and pathway databases

BioCycMGEN243273:GH2R-456-MONOMER.

Family and domain databases

Gene3D1.10.1140.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPMF_01347. ATP_synth_beta_bact.
InterProIPR003593. AAA+_ATPase.
IPR020003. ATPase_a/bsu_AS.
IPR005722. ATPase_F1-cplx_bsu.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR004100. ATPase_F1_a/bsu_N.
IPR024034. ATPase_F1_bsu/V1_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERPTHR15184:SF8. PTHR15184:SF8. 1 hit.
PfamPF00006. ATP-synt_ab. 1 hit.
PF00306. ATP-synt_ab_C. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF47917. SSF47917. 1 hit.
SSF50615. SSF50615. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR01039. atpD. 1 hit.
PROSITEPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATPB_MYCGE
AccessionPrimary (citable) accession number: P47639
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: November 1, 1997
Last modified: May 14, 2014
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma genitalium

Mycoplasma genitalium (strain G-37): entries and gene names