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P47636

- RPIB_MYCGE

UniProt

P47636 - RPIB_MYCGE

Protein

Probable ribose-5-phosphate isomerase B

Gene

rpiB

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-ribose 5-phosphate = D-ribulose 5-phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei11 – 111SubstrateBy similarity
    Active sitei69 – 691Proton acceptorSequence Analysis
    Active sitei102 – 1021Proton donorBy similarity
    Binding sitei113 – 1131SubstrateBy similarity
    Binding sitei136 – 1361SubstrateBy similarity
    Binding sitei140 – 1401SubstrateBy similarity

    GO - Molecular functioni

    1. ribose-5-phosphate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pentose-phosphate shunt Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Carbohydrate metabolism

    Enzyme and pathway databases

    BioCyciMGEN243273:GH2R-453-MONOMER.
    UniPathwayiUPA00115; UER00412.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable ribose-5-phosphate isomerase B (EC:5.3.1.6)
    Alternative name(s):
    Phosphoriboisomerase B
    Gene namesi
    Name:rpiB
    Ordered Locus Names:MG396
    OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
    Taxonomic identifieri243273 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000000807: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 152152Probable ribose-5-phosphate isomerase BPRO_0000208165Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Protein-protein interaction databases

    STRINGi243273.MG_396.

    Structurei

    3D structure databases

    ProteinModelPortaliP47636.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni70 – 756Substrate bindingBy similarity

    Sequence similaritiesi

    Belongs to the LacAB/RpiB family.Curated

    Phylogenomic databases

    eggNOGiCOG0698.
    KOiK01808.
    OMAiAYEDSHA.
    OrthoDBiEOG679TJ4.

    Family and domain databases

    Gene3Di3.40.1400.10. 1 hit.
    InterProiIPR004785. RpiB.
    IPR003500. RpiB_LacA_LacB.
    [Graphical view]
    PANTHERiPTHR30345. PTHR30345. 1 hit.
    PfamiPF02502. LacAB_rpiB. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005384. RpiB_LacA_B. 1 hit.
    SUPFAMiSSF89623. SSF89623. 1 hit.
    TIGRFAMsiTIGR01120. rpiB. 1 hit.
    TIGR00689. rpiB_lacA_lacB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P47636-1 [UniParc]FASTAAdd to Basket

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    MSFNIFIASD HTGLTLKKII SEHLKTKQFN VVDLGPNYFD ANDDYPDFAF    50
    LVADKVKKNS DKDLGILICG TGVGVCMAAN KVKGVLAALV VSEKTAALAR 100
    QHDNANVLCL SSRFVTDSEN IKIVDDFLKA NFEGGRHQRR IDKIIRYEKE 150
    TE 152
    Length:152
    Mass (Da):16,893
    Last modified:October 1, 1996 - v1
    Checksum:i1D5A15E5C14F74DB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L43967 Genomic DNA. Translation: AAC71624.1.
    PIRiH64243.
    RefSeqiNP_073069.1. NC_000908.2.

    Genome annotation databases

    EnsemblBacteriaiAAC71624; AAC71624; MG_396.
    GeneIDi875657.
    KEGGimge:MG_396.
    PATRICi20010380. VBIMycGen98045_0463.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L43967 Genomic DNA. Translation: AAC71624.1 .
    PIRi H64243.
    RefSeqi NP_073069.1. NC_000908.2.

    3D structure databases

    ProteinModelPortali P47636.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243273.MG_396.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC71624 ; AAC71624 ; MG_396 .
    GeneIDi 875657.
    KEGGi mge:MG_396.
    PATRICi 20010380. VBIMycGen98045_0463.

    Phylogenomic databases

    eggNOGi COG0698.
    KOi K01808.
    OMAi AYEDSHA.
    OrthoDBi EOG679TJ4.

    Enzyme and pathway databases

    UniPathwayi UPA00115 ; UER00412 .
    BioCyci MGEN243273:GH2R-453-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1400.10. 1 hit.
    InterProi IPR004785. RpiB.
    IPR003500. RpiB_LacA_LacB.
    [Graphical view ]
    PANTHERi PTHR30345. PTHR30345. 1 hit.
    Pfami PF02502. LacAB_rpiB. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005384. RpiB_LacA_B. 1 hit.
    SUPFAMi SSF89623. SSF89623. 1 hit.
    TIGRFAMsi TIGR01120. rpiB. 1 hit.
    TIGR00689. rpiB_lacA_lacB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33530 / G-37 / NCTC 10195.

    Entry informationi

    Entry nameiRPIB_MYCGE
    AccessioniPrimary (citable) accession number: P47636
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Mycoplasma genitalium
      Mycoplasma genitalium (strain G-37): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3