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P47619

- MNMG_MYCGE

UniProt

P47619 - MNMG_MYCGE

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Protein

tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

Gene

mnmG

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34.UniRule annotation

Cofactori

FAD.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi9 – 146FADUniRule annotation
Nucleotide bindingi270 – 28415NADUniRule annotationAdd
BLAST

GO - Molecular functioni

  1. flavin adenine dinucleotide binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. tRNA wobble uridine modification Source: InterPro
Complete GO annotation...

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

FAD, Flavoprotein, NAD

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-434-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGUniRule annotation
Alternative name(s):
Glucose-inhibited division protein AUniRule annotation
Gene namesi
Name:mnmGUniRule annotation
Synonyms:gidAUniRule annotation
Ordered Locus Names:MG379
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 612612tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGPRO_0000117132Add
BLAST

Interactioni

Subunit structurei

Homodimer. Heterotetramer of two MnmE and two MnmG subunits.UniRule annotation

Protein-protein interaction databases

STRINGi243273.MG_379.

Structurei

3D structure databases

ProteinModelPortaliP47619.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MnmG family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0445.
KOiK03495.
OMAiHTNEQTH.
OrthoDBiEOG6W9X6J.

Family and domain databases

HAMAPiMF_00129. MnmG_GidA.
InterProiIPR004416. GidA.
IPR026904. GidA-assoc_3.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view]
PfamiPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc_3. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00136. gidA. 1 hit.
PROSITEiPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47619-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSFIITVIGA GHAGLEAAFI VSKFNIKVNL LVLDINHLGS CPCNPSIGGP
60 70 80 90 100
AKGIVTREID VLGGMQAIAA DNNALQYKLL NSSKGPAVQA IRAQIDKIGY
110 120 130 140 150
KNWFQSQVKL NKNINLIQSE AINLIVRNEK IKGVILKDGS ELLSDAVIIT
160 170 180 190 200
TGTYLRSKTY CGNTVKNQGP DQSKNSEKLS TNLINRGFKT IRLKTGTPPR
210 220 230 240 250
ILKTSLDYNQ MELEINNNQN LAFSTTNKNF LPLEKQIPCY LVHTNQKIHD
260 270 280 290 300
LILKNLKKSA MFNGSISAQG PLYCPSIEDK VFKFSQKPRH QIFVEPESLS
310 320 330 340 350
LDTIYLAGLS TSFTPEIQKE IIQLLPGFQN AEIKKFGYAI EYDAFLSNQL
360 370 380 390 400
KPTLETKLIE NLYFAGQING TSGYEEAAGQ GLMAGINAAL KLLKKPPFIL
410 420 430 440 450
QRNEAYIGVM INDLVTKTIS DPYRLLTSRA EYRLWLRNDN VQERLIKKSF
460 470 480 490 500
ELGLTDKKTY ELFLKKEKKK QELISFLKNT QVGKVKALKF TNKNTAQSLY
510 520 530 540 550
DFNKRSEINL DKLIKDLPEK YQLDSETLKQ IEIEIKYEGY IKKNEKYFKG
560 570 580 590 600
LDKLSKIKIP HTFDYHKVKN LASEAIFKLS NFKPSNLAIA SQIAGVNFND
610
IIAIKHFLKT YE
Length:612
Mass (Da):68,995
Last modified:February 1, 1996 - v1
Checksum:i67A3F64C985B5912
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43967 Genomic DNA. Translation: AAC71606.1.
U01812 Genomic DNA. Translation: AAD12347.1.
PIRiI64241.
RefSeqiNP_073051.1. NC_000908.2.
WP_010869458.1. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC71606; AAC71606; MG_379.
GeneIDi875674.
KEGGimge:MG_379.
PATRICi20010340. VBIMycGen98045_0444.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43967 Genomic DNA. Translation: AAC71606.1 .
U01812 Genomic DNA. Translation: AAD12347.1 .
PIRi I64241.
RefSeqi NP_073051.1. NC_000908.2.
WP_010869458.1. NC_000908.2.

3D structure databases

ProteinModelPortali P47619.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243273.MG_379.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC71606 ; AAC71606 ; MG_379 .
GeneIDi 875674.
KEGGi mge:MG_379.
PATRICi 20010340. VBIMycGen98045_0444.

Phylogenomic databases

eggNOGi COG0445.
KOi K03495.
OMAi HTNEQTH.
OrthoDBi EOG6W9X6J.

Enzyme and pathway databases

BioCyci MGEN243273:GH2R-434-MONOMER.

Family and domain databases

HAMAPi MF_00129. MnmG_GidA.
InterProi IPR004416. GidA.
IPR026904. GidA-assoc_3.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view ]
Pfami PF01134. GIDA. 1 hit.
PF13932. GIDA_assoc_3. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00136. gidA. 1 hit.
PROSITEi PS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.
  2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
    Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
    J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 301-394.
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiMNMG_MYCGE
AccessioniPrimary (citable) accession number: P47619
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: October 29, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3