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P47619 (MNMG_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
Alternative name(s):
Glucose-inhibited division protein A
Gene names
Name:mnmG
Synonyms:gidA
Ordered Locus Names:MG379
OrganismMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]
Taxonomic identifier243273 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length612 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34 By similarity. HAMAP-Rule MF_00129

Cofactor

FAD By similarity. HAMAP-Rule MF_00129

Subunit structure

Homodimer By similarity. Heterotetramer of two MnmE and two MnmG subunits By similarity. HAMAP-Rule MF_00129

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00129.

Sequence similarities

Belongs to the MnmG family.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentCytoplasm
   LigandFAD
Flavoprotein
NAD
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA wobble uridine modification

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionflavin adenine dinucleotide binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 612612tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG HAMAP-Rule MF_00129
PRO_0000117132

Regions

Nucleotide binding9 – 146FAD By similarity
Nucleotide binding270 – 28415NAD Potential

Sequences

Sequence LengthMass (Da)Tools
P47619 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 67A3F64C985B5912

FASTA61268,995
        10         20         30         40         50         60 
MSFIITVIGA GHAGLEAAFI VSKFNIKVNL LVLDINHLGS CPCNPSIGGP AKGIVTREID 

        70         80         90        100        110        120 
VLGGMQAIAA DNNALQYKLL NSSKGPAVQA IRAQIDKIGY KNWFQSQVKL NKNINLIQSE 

       130        140        150        160        170        180 
AINLIVRNEK IKGVILKDGS ELLSDAVIIT TGTYLRSKTY CGNTVKNQGP DQSKNSEKLS 

       190        200        210        220        230        240 
TNLINRGFKT IRLKTGTPPR ILKTSLDYNQ MELEINNNQN LAFSTTNKNF LPLEKQIPCY 

       250        260        270        280        290        300 
LVHTNQKIHD LILKNLKKSA MFNGSISAQG PLYCPSIEDK VFKFSQKPRH QIFVEPESLS 

       310        320        330        340        350        360 
LDTIYLAGLS TSFTPEIQKE IIQLLPGFQN AEIKKFGYAI EYDAFLSNQL KPTLETKLIE 

       370        380        390        400        410        420 
NLYFAGQING TSGYEEAAGQ GLMAGINAAL KLLKKPPFIL QRNEAYIGVM INDLVTKTIS 

       430        440        450        460        470        480 
DPYRLLTSRA EYRLWLRNDN VQERLIKKSF ELGLTDKKTY ELFLKKEKKK QELISFLKNT 

       490        500        510        520        530        540 
QVGKVKALKF TNKNTAQSLY DFNKRSEINL DKLIKDLPEK YQLDSETLKQ IEIEIKYEGY 

       550        560        570        580        590        600 
IKKNEKYFKG LDKLSKIKIP HTFDYHKVKN LASEAIFKLS NFKPSNLAIA SQIAGVNFND 

       610 
IIAIKHFLKT YE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L43967 Genomic DNA. Translation: AAC71606.1.
U01812 Genomic DNA. Translation: AAD12347.1.
PIRI64241.
RefSeqNP_073051.1. NC_000908.2.

3D structure databases

ProteinModelPortalP47619.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243273.MG_379.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC71606; AAC71606; MG_379.
GeneID875674.
KEGGmge:MG_379.
PATRIC20010340. VBIMycGen98045_0444.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0445.
KOK03495.
OMAYINGLST.
OrthoDBEOG6W9X6J.
ProtClustDBPRK05192.

Enzyme and pathway databases

BioCycMGEN243273:GH2R-434-MONOMER.

Family and domain databases

HAMAPMF_00129. MnmG_GidA.
InterProIPR004416. GidA.
IPR026904. GidA-assoc_3.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view]
PfamPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc_3. 1 hit.
[Graphical view]
TIGRFAMsTIGR00136. gidA. 1 hit.
PROSITEPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMNMG_MYCGE
AccessionPrimary (citable) accession number: P47619
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: February 19, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma genitalium

Mycoplasma genitalium (strain G-37): entries and gene names