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P47610

- Y370_MYCGE

UniProt

P47610 - Y370_MYCGE

Protein

Uncharacterized RNA pseudouridine synthase MG370

Gene

MG370

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    RNA uridine = RNA pseudouridine.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei148 – 1481By similarity

    GO - Molecular functioni

    1. pseudouridine synthase activity Source: InterPro
    2. RNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. pseudouridine synthesis Source: InterPro

    Keywords - Molecular functioni

    Isomerase

    Keywords - Ligandi

    RNA-binding

    Enzyme and pathway databases

    BioCyciMGEN243273:GH2R-425-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized RNA pseudouridine synthase MG370 (EC:5.4.99.-)
    Alternative name(s):
    RNA pseudouridylate synthase
    RNA-uridine isomerase
    Gene namesi
    Ordered Locus Names:MG370
    OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
    Taxonomic identifieri243273 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000000807: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 323323Uncharacterized RNA pseudouridine synthase MG370PRO_0000162741Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243273.MG_370.

    Structurei

    3D structure databases

    ProteinModelPortaliP47610.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini16 – 9580S4 RNA-bindingPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the pseudouridine synthase RluA family.Curated
    Contains 1 S4 RNA-binding domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0564.
    KOiK06179.
    OMAiCIFFADE.
    OrthoDBiEOG6P070X.

    Family and domain databases

    InterProiIPR020103. PsdUridine_synth_cat_dom.
    IPR006225. PsdUridine_synth_RluC/D.
    IPR006224. PsdUridine_synth_RluC/D_CS.
    IPR006145. PsdUridine_synth_RsuA/RluD.
    IPR002942. S4_RNA-bd.
    [Graphical view]
    PfamiPF00849. PseudoU_synth_2. 1 hit.
    [Graphical view]
    SMARTiSM00363. S4. 1 hit.
    [Graphical view]
    SUPFAMiSSF55120. SSF55120. 1 hit.
    TIGRFAMsiTIGR00005. rluA_subfam. 1 hit.
    PROSITEiPS01129. PSI_RLU. 1 hit.
    PS50889. S4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P47610-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRIANKFLVP KESENQRIDQ FCLKILPLIK RSDFFKYLRL GKVLLNKTKP    50
    QVNTRLKTKD EIAFLFDINP YLQTNNDYLS LDLVKDKLKI IFEDENIIVV 100
    DKPTGIVCQP DKKHSIINLS NMLLKHCGYR QFDSNKLNFY PQFAHRIDRN 150
    TSGIVIGAKT NKALKELNKV FKNNHLTKRY KGLVFGQFNH LGLQTAYWKK 200
    DNNNGIVTVK WKPFPEAKKI STFFENSSYI AQKDMSLITI RLISGRTHQI 250
    RACLNLFSNQ LVGDKKYSLI QFKNRNNKYK HQALHAYELV FPKLETSKFP 300
    ILTNYSLMQF KSKIVPWFEY LIQ 323
    Length:323
    Mass (Da):37,948
    Last modified:February 1, 1996 - v1
    Checksum:i0A0897B8C7367FB8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L43967 Genomic DNA. Translation: AAC71597.1.
    U02220 Genomic DNA. Translation: AAA03374.1.
    PIRiI64240.
    RefSeqiNP_073042.1. NC_000908.2.
    WP_010869454.1. NC_000908.2.

    Genome annotation databases

    EnsemblBacteriaiAAC71597; AAC71597; MG_370.
    GeneIDi875682.
    KEGGimge:MG_370.
    PATRICi20010322. VBIMycGen98045_0435.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L43967 Genomic DNA. Translation: AAC71597.1 .
    U02220 Genomic DNA. Translation: AAA03374.1 .
    PIRi I64240.
    RefSeqi NP_073042.1. NC_000908.2.
    WP_010869454.1. NC_000908.2.

    3D structure databases

    ProteinModelPortali P47610.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243273.MG_370.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC71597 ; AAC71597 ; MG_370 .
    GeneIDi 875682.
    KEGGi mge:MG_370.
    PATRICi 20010322. VBIMycGen98045_0435.

    Phylogenomic databases

    eggNOGi COG0564.
    KOi K06179.
    OMAi CIFFADE.
    OrthoDBi EOG6P070X.

    Enzyme and pathway databases

    BioCyci MGEN243273:GH2R-425-MONOMER.

    Family and domain databases

    InterProi IPR020103. PsdUridine_synth_cat_dom.
    IPR006225. PsdUridine_synth_RluC/D.
    IPR006224. PsdUridine_synth_RluC/D_CS.
    IPR006145. PsdUridine_synth_RsuA/RluD.
    IPR002942. S4_RNA-bd.
    [Graphical view ]
    Pfami PF00849. PseudoU_synth_2. 1 hit.
    [Graphical view ]
    SMARTi SM00363. S4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55120. SSF55120. 1 hit.
    TIGRFAMsi TIGR00005. rluA_subfam. 1 hit.
    PROSITEi PS01129. PSI_RLU. 1 hit.
    PS50889. S4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33530 / G-37 / NCTC 10195.
    2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
      Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
      J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 81-199.
      Strain: ATCC 33530 / G-37 / NCTC 10195.

    Entry informationi

    Entry nameiY370_MYCGE
    AccessioniPrimary (citable) accession number: P47610
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Mycoplasma genitalium
      Mycoplasma genitalium (strain G-37): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3