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P47610 (Y370_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized RNA pseudouridine synthase MG370

EC=5.4.99.-
Alternative name(s):
RNA pseudouridylate synthase
RNA-uridine isomerase
Gene names
Ordered Locus Names:MG370
OrganismMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]
Taxonomic identifier243273 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length323 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

RNA uridine = RNA pseudouridine.

Sequence similarities

Belongs to the pseudouridine synthase RluA family.

Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
   LigandRNA-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpseudouridine synthesis

Inferred from electronic annotation. Source: InterPro

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

pseudouridine synthase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 323323Uncharacterized RNA pseudouridine synthase MG370
PRO_0000162741

Regions

Domain16 – 9580S4 RNA-binding

Sites

Active site1481 By similarity

Sequences

Sequence LengthMass (Da)Tools
P47610 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 0A0897B8C7367FB8

FASTA32337,948
        10         20         30         40         50         60 
MRIANKFLVP KESENQRIDQ FCLKILPLIK RSDFFKYLRL GKVLLNKTKP QVNTRLKTKD 

        70         80         90        100        110        120 
EIAFLFDINP YLQTNNDYLS LDLVKDKLKI IFEDENIIVV DKPTGIVCQP DKKHSIINLS 

       130        140        150        160        170        180 
NMLLKHCGYR QFDSNKLNFY PQFAHRIDRN TSGIVIGAKT NKALKELNKV FKNNHLTKRY 

       190        200        210        220        230        240 
KGLVFGQFNH LGLQTAYWKK DNNNGIVTVK WKPFPEAKKI STFFENSSYI AQKDMSLITI 

       250        260        270        280        290        300 
RLISGRTHQI RACLNLFSNQ LVGDKKYSLI QFKNRNNKYK HQALHAYELV FPKLETSKFP 

       310        320 
ILTNYSLMQF KSKIVPWFEY LIQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L43967 Genomic DNA. Translation: AAC71597.1.
U02220 Genomic DNA. Translation: AAA03374.1.
PIRI64240.
RefSeqNP_073042.1. NC_000908.2.

3D structure databases

ProteinModelPortalP47610.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243273.MG_370.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC71597; AAC71597; MG_370.
GeneID875682.
KEGGmge:MG_370.
PATRIC20010322. VBIMycGen98045_0435.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0564.
KOK06179.
OMACIFFADE.
OrthoDBEOG6P070X.

Enzyme and pathway databases

BioCycMGEN243273:GH2R-425-MONOMER.

Family and domain databases

InterProIPR020103. PsdUridine_synth_cat_dom.
IPR006225. PsdUridine_synth_RluC/D.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamPF00849. PseudoU_synth_2. 1 hit.
[Graphical view]
SMARTSM00363. S4. 1 hit.
[Graphical view]
SUPFAMSSF55120. SSF55120. 1 hit.
TIGRFAMsTIGR00005. rluA_subfam. 1 hit.
PROSITEPS01129. PSI_RLU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameY370_MYCGE
AccessionPrimary (citable) accession number: P47610
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: May 14, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma genitalium

Mycoplasma genitalium (strain G-37): entries and gene names