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P47547 (DNAK_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chaperone protein DnaK
Alternative name(s):
HSP70
Heat shock 70 kDa protein
Heat shock protein 70
Gene names
Name:dnaK
Synonyms:hsp70
Ordered Locus Names:MG305
OrganismMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]
Taxonomic identifier243273 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length595 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Acts as a chaperone By similarity. HAMAP-Rule MF_00332

Induction

By stress conditions e.g. heat shock By similarity. HAMAP-Rule MF_00332

Sequence similarities

Belongs to the heat shock protein 70 family.

Ontologies

Keywords
   Biological processStress response
   LigandATP-binding
Nucleotide-binding
   Molecular functionChaperone
   PTMPhosphoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: InterPro

response to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 595595Chaperone protein DnaK HAMAP-Rule MF_00332
PRO_0000078490

Amino acid modifications

Modified residue1821Phosphothreonine; by autocatalysis By similarity

Experimental info

Sequence conflict447 – 46014PKGKP…TFSLD → LKVNPKLRLPLVWM Ref.2

Sequences

Sequence LengthMass (Da)Tools
P47547 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 8EB48D058A009FB7

FASTA59565,051
        10         20         30         40         50         60 
MSADNGLIIG IDLGTTNSCV SVMEGGRPVV LENPEGKRTT PSIVSYKNNE IIVGDAAKRQ 

        70         80         90        100        110        120 
MVTNPNTIVS IKRLMGTSNK VKVQNADGTT KELSPEQVSA QILSYLKDFA EKKIGKKISR 

       130        140        150        160        170        180 
AVITVPAYFN DAERNATKTA GKIAGLNVER IINEPTAAAL AYGIDKASRE MKVLVYDLGG 

       190        200        210        220        230        240 
GTFDVSLLDI AEGTFEVLAT AGDNRLGGDD WDNKIIEYIS AYIAKEHQGL NLSKDKMAMQ 

       250        260        270        280        290        300 
RLKEAAERAK IELSAQLETI ISLPFLTVTQ KGPVNVELKL TRAKFEELTK PLLERTRNPI 

       310        320        330        340        350        360 
SDVIKEAKIK PEEINEILLV GGSTRMPAVQ KLVESMVPGK KPNRSINPDE VVAIGAAIQG 

       370        380        390        400        410        420 
GVLRGDVKDV LLLDVTPLTL SIETLGGVAT PLIKRNTTIP VSKSQIFSTA QDNQESVDVV 

       430        440        450        460        470        480 
VCQGERPMSR DNKSLGRFNL GGIQPAPKGK PQIEITFSLD ANGILNVKAK DLTTQKENSI 

       490        500        510        520        530        540 
TISDNGNLSE EEIQKMIRDA EANKERDNII RERIELRNEG EGIVNTIKEI LASPDAKNFP 

       550        560        570        580        590 
KEEKEKLEKL TGNIDAAIKA NDYAKLKVEI ENFKKWREEM AKKYNPTGEQ GPQAK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L43967 Genomic DNA. Translation: AAC71527.1.
U02204 Genomic DNA. Translation: AAD12493.1.
PIRG64233.
RefSeqNP_072972.1. NC_000908.2.

3D structure databases

ProteinModelPortalP47547.
SMRP47547. Positions 8-516.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243273.MG_305.

Proteomic databases

PRIDEP47547.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC71527; AAC71527; MG_305.
GeneID875435.
KEGGmge:MG_305.
PATRIC20010140. VBIMycGen98045_0356.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0443.
KOK04043.
OMAMITKNTT.
OrthoDBEOG6JMMSV.
ProtClustDBPRK00290.

Enzyme and pathway databases

BioCycMGEN243273:GH2R-341-MONOMER.

Family and domain databases

HAMAPMF_00332. DnaK.
InterProIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSPR00301. HEATSHOCK70.
TIGRFAMsTIGR02350. prok_dnaK. 1 hit.
PROSITEPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDNAK_MYCGE
AccessionPrimary (citable) accession number: P47547
Secondary accession number(s): Q49321
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: February 19, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma genitalium

Mycoplasma genitalium (strain G-37): entries and gene names