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P47547

- DNAK_MYCGE

UniProt

P47547 - DNAK_MYCGE

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Protein
Chaperone protein DnaK
Gene
dnaK, hsp70, MG305
Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Acts as a chaperone By similarity.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. protein folding Source: InterPro
  2. response to stress Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-341-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaK
Alternative name(s):
HSP70
Heat shock 70 kDa protein
Heat shock protein 70
Gene namesi
Name:dnaK
Synonyms:hsp70
Ordered Locus Names:MG305
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 595595Chaperone protein DnaKUniRule annotation
PRO_0000078490Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei182 – 1821Phosphothreonine; by autocatalysis By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiP47547.

Expressioni

Inductioni

By stress conditions e.g. heat shock By similarity.UniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi243273.MG_305.

Structurei

3D structure databases

ProteinModelPortaliP47547.
SMRiP47547. Positions 8-516.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0443.
KOiK04043.
OMAiQRDVAIM.
OrthoDBiEOG6JMMSV.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47547-1 [UniParc]FASTAAdd to Basket

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MSADNGLIIG IDLGTTNSCV SVMEGGRPVV LENPEGKRTT PSIVSYKNNE    50
IIVGDAAKRQ MVTNPNTIVS IKRLMGTSNK VKVQNADGTT KELSPEQVSA 100
QILSYLKDFA EKKIGKKISR AVITVPAYFN DAERNATKTA GKIAGLNVER 150
IINEPTAAAL AYGIDKASRE MKVLVYDLGG GTFDVSLLDI AEGTFEVLAT 200
AGDNRLGGDD WDNKIIEYIS AYIAKEHQGL NLSKDKMAMQ RLKEAAERAK 250
IELSAQLETI ISLPFLTVTQ KGPVNVELKL TRAKFEELTK PLLERTRNPI 300
SDVIKEAKIK PEEINEILLV GGSTRMPAVQ KLVESMVPGK KPNRSINPDE 350
VVAIGAAIQG GVLRGDVKDV LLLDVTPLTL SIETLGGVAT PLIKRNTTIP 400
VSKSQIFSTA QDNQESVDVV VCQGERPMSR DNKSLGRFNL GGIQPAPKGK 450
PQIEITFSLD ANGILNVKAK DLTTQKENSI TISDNGNLSE EEIQKMIRDA 500
EANKERDNII RERIELRNEG EGIVNTIKEI LASPDAKNFP KEEKEKLEKL 550
TGNIDAAIKA NDYAKLKVEI ENFKKWREEM AKKYNPTGEQ GPQAK 595
Length:595
Mass (Da):65,051
Last modified:February 1, 1996 - v1
Checksum:i8EB48D058A009FB7
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti447 – 46014PKGKP…TFSLD → LKVNPKLRLPLVWM1 Publication
Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43967 Genomic DNA. Translation: AAC71527.1.
U02204 Genomic DNA. Translation: AAD12493.1.
PIRiG64233.
RefSeqiNP_072972.1. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC71527; AAC71527; MG_305.
GeneIDi875435.
KEGGimge:MG_305.
PATRICi20010140. VBIMycGen98045_0356.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43967 Genomic DNA. Translation: AAC71527.1 .
U02204 Genomic DNA. Translation: AAD12493.1 .
PIRi G64233.
RefSeqi NP_072972.1. NC_000908.2.

3D structure databases

ProteinModelPortali P47547.
SMRi P47547. Positions 8-516.
ModBasei Search...

Protein-protein interaction databases

STRINGi 243273.MG_305.

Proteomic databases

PRIDEi P47547.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC71527 ; AAC71527 ; MG_305 .
GeneIDi 875435.
KEGGi mge:MG_305.
PATRICi 20010140. VBIMycGen98045_0356.

Phylogenomic databases

eggNOGi COG0443.
KOi K04043.
OMAi QRDVAIM.
OrthoDBi EOG6JMMSV.

Enzyme and pathway databases

BioCyci MGEN243273:GH2R-341-MONOMER.

Family and domain databases

Gene3Di 1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPi MF_00332. DnaK.
InterProi IPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view ]
Pfami PF00012. HSP70. 1 hit.
[Graphical view ]
PRINTSi PR00301. HEATSHOCK70.
SUPFAMi SSF100920. SSF100920. 1 hit.
TIGRFAMsi TIGR02350. prok_dnaK. 1 hit.
PROSITEi PS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.
  2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
    Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
    J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 353-460.
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiDNAK_MYCGE
AccessioniPrimary (citable) accession number: P47547
Secondary accession number(s): Q49321
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: June 11, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi