ID   P69_MYCGE               Reviewed;         543 AA.
AC   P47533; Q49219; Q49294;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   27-MAR-2024, entry version 119.
DE   RecName: Full=ABC transport system permease protein p69;
GN   Name=p69; OrderedLocusNames=MG291;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Mycoplasmatota; Mycoplasmoidales; Mycoplasmoidaceae;
OC   Mycoplasmoides.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-93 AND 406-530.
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA   Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT   "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL   J. Bacteriol. 175:7918-7930(1993).
CC   -!- FUNCTION: Probably part of a high-affinity transport system.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- DOMAIN: Composed of two homologous domains.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD12453.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; L43967; AAC71512.1; -; Genomic_DNA.
DR   EMBL; U02171; AAD12453.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U01768; AAD10585.1; -; Genomic_DNA.
DR   PIR; B64232; B64232.
DR   RefSeq; WP_010869410.1; NC_000908.2.
DR   AlphaFoldDB; P47533; -.
DR   SMR; P47533; -.
DR   STRING; 243273.MG_291; -.
DR   KEGG; mge:MG_291; -.
DR   eggNOG; COG3639; Bacteria.
DR   HOGENOM; CLU_479675_0_0_14; -.
DR   InParanoid; P47533; -.
DR   OrthoDB; 401373at2; -.
DR   BioCyc; MGEN243273:G1GJ2-359-MONOMER; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   Gene3D; 1.10.3720.10; MetI-like; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   PANTHER; PTHR30043; PHOSPHONATES TRANSPORT SYSTEM PERMEASE PROTEIN; 1.
DR   PANTHER; PTHR30043:SF1; PHOSPHONATES-BINDING PERIPLASMIC PROTEIN; 1.
DR   SUPFAM; SSF161098; MetI-like; 2.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..543
FT                   /note="ABC transport system permease protein p69"
FT                   /id="PRO_0000060169"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        115..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        237..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        288..308
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        354..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        379..399
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        413..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        482..502
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        510..530
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          74..256
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   CONFLICT        519..530
FT                   /note="YLIAIEIIFLSV -> LSNCNRNNFSFS (in Ref. 2)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   543 AA;  63076 MW;  86D3787008839987 CRC64;
     MITKLFFHQV GDNKKRLIWY WKLLIIIAVL AIVIYSWIDN FSSFNQFGLN VFINNITSLF
     TPNLNHEYTL VRFLAQTAFF VTGGSFLGFI FAILFSYWTA FKIQPFYIAL PIRLITIVLR
     AFPVLLFGFL FSNLFNKQLA ATLTISWFSF LWNTKYITTF FENSNLKYFF NKKIREGSGF
     KAFWTTIFLS ENERLWLFFL YSLEANFRWT TLLSIFGIGG IGQLIVDPLS IRVQFDLVLI
     PLVVLITFLI FIEVVVFLLS SFVFEKNSED LRPILKTTVI EKRKWKRIIF ILFIVVLISL
     SLANLVTIDY RINDAEFLQD FFNQFFQLKS NLFSSNDPNI NPILMLVKLT TQAISLISLV
     VIFSILFGFI SCNLFKKRFS ISFKILLLFV RVVPSILLFR LLDPLFLEAK TTIILVLLIN
     HGSSYGQLMS INFNKANQNI INNYKNHGMT KGFILWNYLL VENKPNLINI TSDAYDSVIR
     DLILFGSFGG SIIGSRITNF FERAQFDNLG SVTIPLMVYL IAIEIIFLSV RLTRISVFKN
     YLY
//