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Protein

ABC transport system permease protein p69

Gene

p69

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Probably part of a high-affinity transport system.

GO - Biological processi

  1. transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-326-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transport system permease protein p69
Gene namesi
Name:p69
Ordered Locus Names:MG291
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

Subcellular locationi

Cell membrane Curated; Multi-pass membrane protein PROSITE-ProRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei18 – 3821HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei78 – 9821HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei115 – 13521HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei141 – 16121HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei211 – 23121HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei237 – 25721HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei288 – 30821HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei354 – 37421HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei379 – 39921HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei413 – 43321HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei482 – 50221HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei510 – 53021HelicalPROSITE-ProRule annotationAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 543543ABC transport system permease protein p69PRO_0000060169Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243273.MG_291.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini74 – 256183ABC transmembrane type-1PROSITE-ProRule annotationAdd
BLAST

Domaini

Composed of two homologous domains.

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG3639.
KOiK02042.
OMAiFESNIRW.
OrthoDBiEOG6TR09N.

Family and domain databases

InterProiIPR000515. MetI-like.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 2 hits.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47533-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITKLFFHQV GDNKKRLIWY WKLLIIIAVL AIVIYSWIDN FSSFNQFGLN
60 70 80 90 100
VFINNITSLF TPNLNHEYTL VRFLAQTAFF VTGGSFLGFI FAILFSYWTA
110 120 130 140 150
FKIQPFYIAL PIRLITIVLR AFPVLLFGFL FSNLFNKQLA ATLTISWFSF
160 170 180 190 200
LWNTKYITTF FENSNLKYFF NKKIREGSGF KAFWTTIFLS ENERLWLFFL
210 220 230 240 250
YSLEANFRWT TLLSIFGIGG IGQLIVDPLS IRVQFDLVLI PLVVLITFLI
260 270 280 290 300
FIEVVVFLLS SFVFEKNSED LRPILKTTVI EKRKWKRIIF ILFIVVLISL
310 320 330 340 350
SLANLVTIDY RINDAEFLQD FFNQFFQLKS NLFSSNDPNI NPILMLVKLT
360 370 380 390 400
TQAISLISLV VIFSILFGFI SCNLFKKRFS ISFKILLLFV RVVPSILLFR
410 420 430 440 450
LLDPLFLEAK TTIILVLLIN HGSSYGQLMS INFNKANQNI INNYKNHGMT
460 470 480 490 500
KGFILWNYLL VENKPNLINI TSDAYDSVIR DLILFGSFGG SIIGSRITNF
510 520 530 540
FERAQFDNLG SVTIPLMVYL IAIEIIFLSV RLTRISVFKN YLY
Length:543
Mass (Da):63,076
Last modified:February 1, 1996 - v1
Checksum:i86D3787008839987
GO

Sequence cautioni

The sequence AAD12453.1 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti519 – 53012YLIAI…IFLSV → LSNCNRNNFSFS (PubMed:8253680).CuratedAdd
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71512.1.
U02171 Genomic DNA. Translation: AAD12453.1. Different initiation.
U01768 Genomic DNA. Translation: AAD10585.1.
PIRiB64232.
RefSeqiNP_072957.1. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC71512; AAC71512; MG_291.
GeneIDi875242.
KEGGimge:MG_291.
PATRICi20010110. VBIMycGen98045_0341.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71512.1.
U02171 Genomic DNA. Translation: AAD12453.1. Different initiation.
U01768 Genomic DNA. Translation: AAD10585.1.
PIRiB64232.
RefSeqiNP_072957.1. NC_000908.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243273.MG_291.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC71512; AAC71512; MG_291.
GeneIDi875242.
KEGGimge:MG_291.
PATRICi20010110. VBIMycGen98045_0341.

Phylogenomic databases

eggNOGiCOG3639.
KOiK02042.
OMAiFESNIRW.
OrthoDBiEOG6TR09N.

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-326-MONOMER.

Family and domain databases

InterProiIPR000515. MetI-like.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 2 hits.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.
  2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
    Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
    J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-93 AND 406-530.
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiP69_MYCGE
AccessioniPrimary (citable) accession number: P47533
Secondary accession number(s): Q49219, Q49294
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: January 7, 2015
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.