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Protein

Putative phosphatase MG263

Gene

MG263

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Mg2+By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei11 – 111NucleophileBy similarity
Metal bindingi11 – 111MagnesiumBy similarity
Binding sitei12 – 121Phosphate; via amide nitrogenBy similarity
Metal bindingi13 – 131Magnesium; via carbonyl oxygenBy similarity
Binding sitei217 – 2171PhosphateBy similarity
Metal bindingi241 – 2411MagnesiumBy similarity
Binding sitei244 – 2441PhosphateBy similarity

GO - Molecular functioni

  1. hydrolase activity Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-290-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative phosphatase MG263 (EC:3.1.3.-)
Gene namesi
Ordered Locus Names:MG263
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 291291Putative phosphatase MG263PRO_0000054437Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243273.MG_263.

Structurei

3D structure databases

ProteinModelPortaliP47505.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni60 – 612Phosphate bindingBy similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0561.
KOiK07024.
OMAiTIVSWNP.
OrthoDBiEOG6K13W0.

Family and domain databases

Gene3Di3.40.50.1000. 2 hits.
InterProiIPR023214. HAD-like_dom.
IPR006379. HAD-SF_hydro_IIB.
IPR000150. Hypothet_cof.
[Graphical view]
PfamiPF08282. Hydrolase_3. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR00099. Cof-subfamily. 1 hit.
TIGR01484. HAD-SF-IIB. 1 hit.
PROSITEiPS01228. COF_1. 1 hit.
PS01229. COF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47505-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKNEIKYLYS DLDGTIVSWN PKTEFVYQNK SYKNFHEVSD ATISAFYRLQ
60 70 80 90 100
QKGIKVGIVT GRDYCRVLWL EKQLRTGLPT ITLDGAIIFY QNEILSQTYL
110 120 130 140 150
DDRFIEGINN IVKRFPEAAY KLNSGWISYF TKNPSVIFEI DYAFLGYFNP
160 170 180 190 200
NTKLQKKFID STENWDLNKL KVNQVYFDID TCPLAMQKEI IELISVSDVN
210 220 230 240 250
AKIYEHSMYI IKNGVSKASA LQSLNQFAIP ITKDNTIVCG DGDNDIEMMQ
260 270 280 290
WAKHSVSLIG SNPKCFALAK YHTDSVDNDG IANWIEKNLL C
Length:291
Mass (Da):33,423
Last modified:October 1, 1996 - v1
Checksum:i708EFFEC6158F4B4
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti170 – 1701L → S in AAD10580. (PubMed:8253680)Curated
Sequence conflicti190 – 1901I → R in AAD10580. (PubMed:8253680)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71485.1.
U01764 Genomic DNA. Translation: AAD10580.1.
PIRiA64229.
RefSeqiNP_072930.1. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC71485; AAC71485; MG_263.
GeneIDi875307.
KEGGimge:MG_263.
PATRICi20010026. VBIMycGen98045_0305.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71485.1.
U01764 Genomic DNA. Translation: AAD10580.1.
PIRiA64229.
RefSeqiNP_072930.1. NC_000908.2.

3D structure databases

ProteinModelPortaliP47505.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243273.MG_263.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC71485; AAC71485; MG_263.
GeneIDi875307.
KEGGimge:MG_263.
PATRICi20010026. VBIMycGen98045_0305.

Phylogenomic databases

eggNOGiCOG0561.
KOiK07024.
OMAiTIVSWNP.
OrthoDBiEOG6K13W0.

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-290-MONOMER.

Family and domain databases

Gene3Di3.40.50.1000. 2 hits.
InterProiIPR023214. HAD-like_dom.
IPR006379. HAD-SF_hydro_IIB.
IPR000150. Hypothet_cof.
[Graphical view]
PfamiPF08282. Hydrolase_3. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR00099. Cof-subfamily. 1 hit.
TIGR01484. HAD-SF-IIB. 1 hit.
PROSITEiPS01228. COF_1. 1 hit.
PS01229. COF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.
  2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
    Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
    J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 164-276.
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiY263_MYCGE
AccessioniPrimary (citable) accession number: P47505
Secondary accession number(s): Q49216
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: January 7, 2015
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.