P47490 (Y248_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative tRNA (adenine-N(1)-)-methyltransferase MG248
EC=2.1.1.-

Gene names

Ordered Locus Names:

MG248

Organism

Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]

Taxonomic identifier

243273 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Tenericutes › Mollicutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma genitalium

Protein attributes

Sequence length	218 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N(1)-methyladenine.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the TrmK family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	tRNA (adenine-N1-)-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 218	218	Putative tRNA (adenine-N(1)-)-methyltransferase MG248		PRO_0000210487

Sequences

	Sequence		Length	Mass (Da)
	P47490 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: E213395E1B87CB7D	FASTA	218	25,188
	10 20 30 40 50 60 MKKRISTIAN LVQSFNPKLV YDIGCDHSYL TSYLIKTNQN LTIVNSDISK NALLSNYQKF 70 80 90 100 110 120 KNNNNIHFFV SDGFNNLPEL NINPKIGVIA GLGGLKIINI ISQKENFINR FVIQPQSNLI 130 140 150 160 170 180 ELRSFLSLNS WDIVNETLVQ DREFIYPILV IEKLKKPFKL TKELVILGPK LINFKDKHCL 190 200 210 MKHYQCLLRV YQPKQKPSLM DLKIIETLNK IITSYESS

References

[1]

"The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. , Phillips C.A., Merrick J.M., Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C. Science 270:397-403(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L43967 Genomic DNA. Translation: AAC71468.1.
PIR	D64227.
RefSeq	NP_072913.1. NC_000908.2.
3D structure databases
ProteinModelPortal	P47490.
ModBase	Search...
Protein-protein interaction databases
STRING	243273.MG_248.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC71468; AAC71468; MG_248.
GeneID	875322.
KEGG	mge:MG_248.
PATRIC	20009978. VBIMycGen98045_0285.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2384.
KO	K06967.
OMA	YDIGCDH.
ProtClustDB	CLSK335222.
Enzyme and pathway databases
BioCyc	MGEN243273:GH2R-295-MONOMER.
Family and domain databases
InterPro	IPR006901. TrmK. [Graphical view]
Pfam	PF04816. DUF633. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y248_MYCGE

Accession

Primary (citable) accession number: P47490

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program