P47434 (Y188_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable ABC transporter permease protein MG188

Gene names

Ordered Locus Names:

MG188

Organism

Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]

Taxonomic identifier

243273 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Tenericutes › Mollicutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma genitalium

Protein attributes

Sequence length	329 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.
Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily. Contains 1 ABC transmembrane type-1 domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 329	329	Probable ABC transporter permease protein MG188		PRO_0000060285
Regions
	Transmembrane	30 – 50	21	Helical; Potential
	Transmembrane	96 – 116	21	Helical; Potential
	Transmembrane	128 – 148	21	Helical; Potential
	Transmembrane	176 – 196	21	Helical; Potential
	Transmembrane	234 – 254	21	Helical; Potential
	Transmembrane	283 – 303	21	Helical; Potential
	Domain	88 – 303	216	ABC transmembrane type-1

Sequences

	Sequence		Length	Mass (Da)
	P47434 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 45BFB75ACE8BAE25	FASTA	329	37,201
	10 20 30 40 50 60 MFKWLLKHHN QPHSLQLGLL DQPLPFWKPF LLFLPALLTT ILFTIIPFFL SLQKGFSANS 70 80 90 100 110 120 DLYDLSSQSF SLRTFQDLFS ESNFVLGLRN SFLYSLISLP FSIIIAIVIA SAIVFVYKKL 130 140 150 160 170 180 LRGFWQTVFF LPYVTSGVAI SIAFVYIFDS ASGILNTVFN VNTKWLDSGS RDTFNALWAI 190 200 210 220 230 240 LIFGVWKNLA FNVLIISTAM LSVNPQLYKV ASLDSANPVR QFFKITLPSI RPTLIFLTTL 250 260 270 280 290 300 LILGGMQVFP LALFENKPEE AVANGGNSIL LYIFQQIQSG NTNLAGAATL VLFVLGVCYG 310 320 LVLRNGFYLI EWLQWKIKQL YVQKQLTLY

References

[1]

"The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. , Phillips C.A., Merrick J.M., Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C. Science 270:397-403(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L43967 Genomic DNA. Translation: AAC71407.1.
PIR	H64220.
RefSeq	NP_072851.1. NC_000908.2.
3D structure databases
ProteinModelPortal	P47434.
ModBase	Search...
Protein-protein interaction databases
STRING	243273.MG_188.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC71407; AAC71407; MG_188.
GeneID	875538.
KEGG	mge:MG_188.
PATRIC	20009818. VBIMycGen98045_0215.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1175.
KO	K02025.
OMA	DTFNALW.
ProtClustDB	CLSK782791.
Enzyme and pathway databases
BioCyc	MGEN243273:GH2R-232-MONOMER.
Family and domain databases
InterPro	IPR000515. BPD_transp. [Graphical view]
Pfam	PF00528. BPD_transp_1. 1 hit. [Graphical view]
PROSITE	PS50928. ABC_TM1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y188_MYCGE

Accession

Primary (citable) accession number: P47434

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	May 1, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program