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P47391

- RIBF_MYCGE

UniProt

P47391 - RIBF_MYCGE

Protein

Putative riboflavin biosynthesis protein RibF

Gene

ribF

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + riboflavin = ADP + FMN.
    ATP + FMN = diphosphate + FAD.

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. FMN adenylyltransferase activity Source: UniProtKB-EC
    3. riboflavin kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. FAD biosynthetic process Source: UniProtKB-UniPathway
    2. FMN biosynthetic process Source: UniProtKB-UniPathway
    3. riboflavin biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Kinase, Nucleotidyltransferase, Transferase

    Keywords - Ligandi

    ATP-binding, FAD, Flavoprotein, FMN, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMGEN243273:GH2R-153-MONOMER.
    UniPathwayiUPA00276; UER00406.
    UPA00277; UER00407.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative riboflavin biosynthesis protein RibF
    Including the following 2 domains:
    Riboflavin kinase (EC:2.7.1.26)
    Alternative name(s):
    Flavokinase
    FMN adenylyltransferase (EC:2.7.7.2)
    Alternative name(s):
    FAD pyrophosphorylase
    FAD synthase
    Gene namesi
    Name:ribF
    Ordered Locus Names:MG145
    OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
    Taxonomic identifieri243273 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000000807: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 269269Putative riboflavin biosynthesis protein RibFPRO_0000194145Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243273.MG_145.

    Structurei

    3D structure databases

    ProteinModelPortaliP47391.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RibF family.Curated

    Phylogenomic databases

    eggNOGiCOG0196.
    KOiK11753.
    OrthoDBiEOG6QP0ZV.

    Family and domain databases

    Gene3Di2.40.30.30. 1 hit.
    3.40.50.620. 1 hit.
    InterProiIPR004821. Cyt_trans-like.
    IPR015864. FAD_synthase.
    IPR023468. Riboflavin_kinase.
    IPR002606. Riboflavin_kinase_bac.
    IPR015865. Riboflavin_kinase_bac/euk.
    IPR023465. Riboflavin_kinase_domain.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view]
    PANTHERiPTHR22749. PTHR22749. 1 hit.
    PfamiPF06574. FAD_syn. 1 hit.
    PF01687. Flavokinase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF004491. FAD_Synth. 1 hit.
    SMARTiSM00904. Flavokinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF82114. SSF82114. 1 hit.
    TIGRFAMsiTIGR00125. cyt_tran_rel. 1 hit.
    TIGR00083. ribF. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P47391-1 [UniParc]FASTAAdd to Basket

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    MKSLFIGYFD GLHQGHLFLK QNSKFEPMVL LIDNPPLKQT NWLYDLQQRV    50
    AQIKTYLKAT VEVFDVAKHN MNALSFFEQQ IKRLNCDEII VGTDWHFGND 100
    HKDGIWLKKL FKNTVIVNKT NLSSSVIRNY LTNNELEKAN QLLVEPYYRV 150
    GTVVHGLKKA RLLGFPTANI VMDNHLLTLN KGSYIVRVLL NNQTFYGIGF 200
    ISQKDQDLVC ETHIFNFNNE IYGSLVKFTL LKFIRTISKF SSQAALQKAI 250
    QSDANFALKW LENQNLDKI 269
    Length:269
    Mass (Da):31,091
    Last modified:February 1, 1996 - v1
    Checksum:iA6F669F0450D03B0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L43967 Genomic DNA. Translation: AAC71363.1.
    PIRiA64216.
    RefSeqiNP_072807.1. NC_000908.2.

    Genome annotation databases

    EnsemblBacteriaiAAC71363; AAC71363; MG_145.
    GeneIDi875524.
    KEGGimge:MG_145.
    PATRICi20009720. VBIMycGen98045_0166.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L43967 Genomic DNA. Translation: AAC71363.1 .
    PIRi A64216.
    RefSeqi NP_072807.1. NC_000908.2.

    3D structure databases

    ProteinModelPortali P47391.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243273.MG_145.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC71363 ; AAC71363 ; MG_145 .
    GeneIDi 875524.
    KEGGi mge:MG_145.
    PATRICi 20009720. VBIMycGen98045_0166.

    Phylogenomic databases

    eggNOGi COG0196.
    KOi K11753.
    OrthoDBi EOG6QP0ZV.

    Enzyme and pathway databases

    UniPathwayi UPA00276 ; UER00406 .
    UPA00277 ; UER00407 .
    BioCyci MGEN243273:GH2R-153-MONOMER.

    Family and domain databases

    Gene3Di 2.40.30.30. 1 hit.
    3.40.50.620. 1 hit.
    InterProi IPR004821. Cyt_trans-like.
    IPR015864. FAD_synthase.
    IPR023468. Riboflavin_kinase.
    IPR002606. Riboflavin_kinase_bac.
    IPR015865. Riboflavin_kinase_bac/euk.
    IPR023465. Riboflavin_kinase_domain.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view ]
    PANTHERi PTHR22749. PTHR22749. 1 hit.
    Pfami PF06574. FAD_syn. 1 hit.
    PF01687. Flavokinase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF004491. FAD_Synth. 1 hit.
    SMARTi SM00904. Flavokinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF82114. SSF82114. 1 hit.
    TIGRFAMsi TIGR00125. cyt_tran_rel. 1 hit.
    TIGR00083. ribF. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33530 / G-37 / NCTC 10195.

    Entry informationi

    Entry nameiRIBF_MYCGE
    AccessioniPrimary (citable) accession number: P47391
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Multifunctional enzyme

    Documents

    1. Mycoplasma genitalium
      Mycoplasma genitalium (strain G-37): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3