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P47370 (THIO_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Last modified December 11, 2013. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Thioredoxin

Short name=Trx
Gene names
Name:trxA
Synonyms:trx
Ordered Locus Names:MG124
OrganismMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]
Taxonomic identifier243273 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length102 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions By similarity.

Sequence similarities

Belongs to the thioredoxin family.

Contains 1 thioredoxin domain.

Sequence caution

The sequence AAD12321.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 102102Thioredoxin
PRO_0000120113

Regions

Domain2 – 102101Thioredoxin

Amino acid modifications

Disulfide bond30 ↔ 33Redox-active By similarity

Sequences

Sequence LengthMass (Da)Tools
P47370 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: FC08F02C4170EA2D

FASTA10211,498
        10         20         30         40         50         60 
MVTEIRSLKQ LEEIFSAKKN VIVDFWAAWC GPCKLTSPEF QKAADEFSDA QFVKVNVDDH 

        70         80         90        100 
TDIAAAYNIT SLPTIVVFEN GVEKKRAIGF MPKTKIIDLF NN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L43967 Genomic DNA. Translation: AAC71342.1.
U01796 Genomic DNA. Translation: AAD12321.1. Different initiation.
PIRG64213.
RefSeqNP_072786.1. NC_000908.2.

3D structure databases

ProteinModelPortalP47370.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243273.MG_124.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC71342; AAC71342; MG_124.
GeneID875225.
KEGGmge:MG_124.
PATRIC20009652. VBIMycGen98045_0135.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0526.
OMAINQDEFE.
OrthoDBEOG6QG8RK.
ProtClustDBCLSK542160.

Enzyme and pathway databases

BioCycMGEN243273:GH2R-128-MONOMER.

Family and domain databases

Gene3D3.40.30.10. 1 hit.
InterProIPR005746. Thioredoxin.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
[Graphical view]
PANTHERPTHR10438. PTHR10438. 1 hit.
PfamPF00085. Thioredoxin. 1 hit.
[Graphical view]
PIRSFPIRSF000077. Thioredoxin. 1 hit.
PRINTSPR00421. THIOREDOXIN.
SUPFAMSSF52833. SSF52833. 1 hit.
TIGRFAMsTIGR01068. thioredoxin. 1 hit.
PROSITEPS00194. THIOREDOXIN_1. 1 hit.
PS51352. THIOREDOXIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTHIO_MYCGE
AccessionPrimary (citable) accession number: P47370
Secondary accession number(s): Q49453
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: December 11, 2013
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma genitalium

Mycoplasma genitalium (strain G-37): entries and gene names