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P47370

- THIO_MYCGE

UniProt

P47370 - THIO_MYCGE

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Protein

Thioredoxin

Gene
trxA, trx, MG124
Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions By similarity.

GO - Molecular functioni

  1. protein disulfide oxidoreductase activity Source: InterPro

GO - Biological processi

  1. cell redox homeostasis Source: InterPro
  2. glycerol ether metabolic process Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-128-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thioredoxin
Short name:
Trx
Gene namesi
Name:trxA
Synonyms:trx
Ordered Locus Names:MG124
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 102102ThioredoxinPRO_0000120113Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi30 ↔ 33Redox-active By similarity

Keywords - PTMi

Disulfide bond

Interactioni

Protein-protein interaction databases

STRINGi243273.MG_124.

Structurei

3D structure databases

ProteinModelPortaliP47370.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 102101ThioredoxinAdd
BLAST

Sequence similaritiesi

Belongs to the thioredoxin family.
Contains 1 thioredoxin domain.

Keywords - Domaini

Redox-active center

Phylogenomic databases

eggNOGiCOG0526.
OMAiGAKPKQF.
OrthoDBiEOG6QG8RK.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR005746. Thioredoxin.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
[Graphical view]
PANTHERiPTHR10438. PTHR10438. 1 hit.
PfamiPF00085. Thioredoxin. 1 hit.
[Graphical view]
PIRSFiPIRSF000077. Thioredoxin. 1 hit.
SUPFAMiSSF52833. SSF52833. 1 hit.
TIGRFAMsiTIGR01068. thioredoxin. 1 hit.
PROSITEiPS00194. THIOREDOXIN_1. 1 hit.
PS51352. THIOREDOXIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47370-1 [UniParc]FASTAAdd to Basket

« Hide

MVTEIRSLKQ LEEIFSAKKN VIVDFWAAWC GPCKLTSPEF QKAADEFSDA    50
QFVKVNVDDH TDIAAAYNIT SLPTIVVFEN GVEKKRAIGF MPKTKIIDLF 100
NN 102
Length:102
Mass (Da):11,498
Last modified:February 1, 1996 - v1
Checksum:iFC08F02C4170EA2D
GO

Sequence cautioni

The sequence AAD12321.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43967 Genomic DNA. Translation: AAC71342.1.
U01796 Genomic DNA. Translation: AAD12321.1. Different initiation.
PIRiG64213.
RefSeqiNP_072786.1. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC71342; AAC71342; MG_124.
GeneIDi875225.
KEGGimge:MG_124.
PATRICi20009652. VBIMycGen98045_0135.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43967 Genomic DNA. Translation: AAC71342.1 .
U01796 Genomic DNA. Translation: AAD12321.1 . Different initiation.
PIRi G64213.
RefSeqi NP_072786.1. NC_000908.2.

3D structure databases

ProteinModelPortali P47370.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243273.MG_124.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC71342 ; AAC71342 ; MG_124 .
GeneIDi 875225.
KEGGi mge:MG_124.
PATRICi 20009652. VBIMycGen98045_0135.

Phylogenomic databases

eggNOGi COG0526.
OMAi GAKPKQF.
OrthoDBi EOG6QG8RK.

Enzyme and pathway databases

BioCyci MGEN243273:GH2R-128-MONOMER.

Family and domain databases

Gene3Di 3.40.30.10. 1 hit.
InterProi IPR005746. Thioredoxin.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
[Graphical view ]
PANTHERi PTHR10438. PTHR10438. 1 hit.
Pfami PF00085. Thioredoxin. 1 hit.
[Graphical view ]
PIRSFi PIRSF000077. Thioredoxin. 1 hit.
SUPFAMi SSF52833. SSF52833. 1 hit.
TIGRFAMsi TIGR01068. thioredoxin. 1 hit.
PROSITEi PS00194. THIOREDOXIN_1. 1 hit.
PS51352. THIOREDOXIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.
  2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
    Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
    J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-21.
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiTHIO_MYCGE
AccessioniPrimary (citable) accession number: P47370
Secondary accession number(s): Q49453
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: June 11, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi