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P47357

- G6PI_MYCGE

UniProt

P47357 - G6PI_MYCGE

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Protein
Glucose-6-phosphate isomerase
Gene
pgi, MG111
Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei284 – 2841Proton donor By similarity
Active sitei305 – 3051 By similarity
Active sitei420 – 4201 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-115-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:MG111
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 431431Glucose-6-phosphate isomeraseUniRule annotation
PRO_0000180679Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243273.MG_111.

Structurei

3D structure databases

ProteinModelPortaliP47357.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OMAiQVIFIGN.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47357-1 [UniParc]FASTAAdd to Basket

« Hide

MSDKLLTIDL SHVYGFDKEI IFKKYQKKVD QIHQDFLAHK LADGHMTGWY    50
DQPDQNHQFL LKTINQIDKK FKSLKVTDIV YVGIGGSFTG IKTVLDFLKP 100
KQRTGLKIHF VPDLSAFQAA SVIKEIKNKS WALITTSKSG RTLEPALNFR 150
IFRNLLNKRY GNKHYQRVVV ITDEKKGLLT KMASNHGYQK LVIDSNIGGR 200
FSTLSPAGLL LAKLFGHDPK AILKGTLQAK KDLQTTSLEN NSAYLYAVVR 250
HWLYTTKKFK IEVCIAYHSL YEYLLLQHRQ LFGESEGKND KSLFPTFSIF 300
TVDLHSMGQL YQEGEKVFFE TVIDVKNPLV NINLPPSDFD NDDELDFLLD 350
KSLNEISDVA IDSVIKAHYQ ANVSIIKLTL KEQSAFMFGY FYFWLSVATV 400
MSGSLLGHNV FNQPGVEVYK KLMFEKLRSG H 431
Length:431
Mass (Da):49,253
Last modified:November 2, 2001 - v2
Checksum:iBDAFD77342B3B4F5
GO

Sequence cautioni

The sequence AAC71329.1 differs from that shown. Reason: Erroneous initiation.
The sequence AAD10560.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43967 Genomic DNA. Translation: AAC71329.1. Different initiation.
U01747 Genomic DNA. Translation: AAD10560.1. Different initiation.
RefSeqiNP_072773.2. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC71329; AAC71329; MG_111.
GeneIDi875452.
KEGGimge:MG_111.
PATRICi20009626. VBIMycGen98045_0122.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43967 Genomic DNA. Translation: AAC71329.1 . Different initiation.
U01747 Genomic DNA. Translation: AAD10560.1 . Different initiation.
RefSeqi NP_072773.2. NC_000908.2.

3D structure databases

ProteinModelPortali P47357.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243273.MG_111.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC71329 ; AAC71329 ; MG_111 .
GeneIDi 875452.
KEGGi mge:MG_111.
PATRICi 20009626. VBIMycGen98045_0122.

Phylogenomic databases

eggNOGi COG0166.
KOi K01810.
OMAi QVIFIGN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci MGEN243273:GH2R-115-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.
  2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
    Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
    J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-30.
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiG6PI_MYCGE
AccessioniPrimary (citable) accession number: P47357
Secondary accession number(s): Q49449
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: November 2, 2001
Last modified: June 11, 2014
This is version 89 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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