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P47357

- G6PI_MYCGE

UniProt

P47357 - G6PI_MYCGE

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 2 (02 Nov 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei284 – 2841Proton donorBy similarity
    Active sitei305 – 3051By similarity
    Active sitei420 – 4201By similarity

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciMGEN243273:GH2R-115-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomerase (EC:5.3.1.9)
    Short name:
    GPI
    Alternative name(s):
    Phosphoglucose isomerase
    Short name:
    PGI
    Phosphohexose isomerase
    Short name:
    PHI
    Gene namesi
    Name:pgi
    Ordered Locus Names:MG111
    OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
    Taxonomic identifieri243273 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000000807: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 431431Glucose-6-phosphate isomerasePRO_0000180679Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243273.MG_111.

    Structurei

    3D structure databases

    ProteinModelPortaliP47357.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.Curated

    Phylogenomic databases

    eggNOGiCOG0166.
    KOiK01810.
    OMAiQVIFIGN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P47357-1 [UniParc]FASTAAdd to Basket

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    MSDKLLTIDL SHVYGFDKEI IFKKYQKKVD QIHQDFLAHK LADGHMTGWY    50
    DQPDQNHQFL LKTINQIDKK FKSLKVTDIV YVGIGGSFTG IKTVLDFLKP 100
    KQRTGLKIHF VPDLSAFQAA SVIKEIKNKS WALITTSKSG RTLEPALNFR 150
    IFRNLLNKRY GNKHYQRVVV ITDEKKGLLT KMASNHGYQK LVIDSNIGGR 200
    FSTLSPAGLL LAKLFGHDPK AILKGTLQAK KDLQTTSLEN NSAYLYAVVR 250
    HWLYTTKKFK IEVCIAYHSL YEYLLLQHRQ LFGESEGKND KSLFPTFSIF 300
    TVDLHSMGQL YQEGEKVFFE TVIDVKNPLV NINLPPSDFD NDDELDFLLD 350
    KSLNEISDVA IDSVIKAHYQ ANVSIIKLTL KEQSAFMFGY FYFWLSVATV 400
    MSGSLLGHNV FNQPGVEVYK KLMFEKLRSG H 431
    Length:431
    Mass (Da):49,253
    Last modified:November 2, 2001 - v2
    Checksum:iBDAFD77342B3B4F5
    GO

    Sequence cautioni

    The sequence AAC71329.1 differs from that shown. Reason: Erroneous initiation.
    The sequence AAD10560.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L43967 Genomic DNA. Translation: AAC71329.1. Different initiation.
    U01747 Genomic DNA. Translation: AAD10560.1. Different initiation.
    RefSeqiNP_072773.2. NC_000908.2.

    Genome annotation databases

    EnsemblBacteriaiAAC71329; AAC71329; MG_111.
    GeneIDi875452.
    KEGGimge:MG_111.
    PATRICi20009626. VBIMycGen98045_0122.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L43967 Genomic DNA. Translation: AAC71329.1 . Different initiation.
    U01747 Genomic DNA. Translation: AAD10560.1 . Different initiation.
    RefSeqi NP_072773.2. NC_000908.2.

    3D structure databases

    ProteinModelPortali P47357.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243273.MG_111.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC71329 ; AAC71329 ; MG_111 .
    GeneIDi 875452.
    KEGGi mge:MG_111.
    PATRICi 20009626. VBIMycGen98045_0122.

    Phylogenomic databases

    eggNOGi COG0166.
    KOi K01810.
    OMAi QVIFIGN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci MGEN243273:GH2R-115-MONOMER.

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33530 / G-37 / NCTC 10195.
    2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
      Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
      J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-30.
      Strain: ATCC 33530 / G-37 / NCTC 10195.

    Entry informationi

    Entry nameiG6PI_MYCGE
    AccessioniPrimary (citable) accession number: P47357
    Secondary accession number(s): Q49449
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: November 2, 2001
    Last modified: October 1, 2014
    This is version 90 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Mycoplasma genitalium
      Mycoplasma genitalium (strain G-37): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3