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Protein

Putative serine/threonine-protein kinase

Gene

MG109

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641Proton acceptorPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-113-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative serine/threonine-protein kinase (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:MG109
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 387387Putative serine/threonine-protein kinasePRO_0000171201Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243273.MG_109.

Structurei

3D structure databases

ProteinModelPortaliP47355.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini15 – 344330Protein kinasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0515.
KOiK08884.
OMAiTDENSLF.
OrthoDBiEOG62NX1C.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47355-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAILKIGDI VENKYQIEKL LNRGGMDSYL FLAKNLNLKN YGPVQKKQYG
60 70 80 90 100
HLVLKVVQKN PKINENNWKK FLDEMVTTTR VHHSNLVKSF DVVNPFLKIV
110 120 130 140 150
RGNKTIALNQ IVMIAMEYVD GPSLRQLLNR KGYFSVSEVV YYFTKIVKAI
160 170 180 190 200
DYLHSFKHQI IHRDLKPENI LFTSDLTDIK LLDFGIASTV VKVAEKTEVL
210 220 230 240 250
TDENSLFGTV SYMIPDVLES TVNKAGKKVR KPPNAQYDIY SLGIILFEML
260 270 280 290 300
VGRVPFNKSI NPNKERETIQ KARNFDLPLM QATRSDIPNS LENIAFRCTA
310 320 330 340 350
VKRENNKWLY SSTKELLEDL ANWENEQAMI KPANERVLEG QVEIREMMLE
360 370 380
KPLAWYFKTW ALSIFTIVFI GLIIAAIVLL LIFNARF
Length:387
Mass (Da):44,626
Last modified:November 1, 1997 - v2
Checksum:i346D35DDF2C15610
GO

Sequence cautioni

The sequence AAC71327.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71327.1. Different initiation.
U01720 Unassigned DNA. Translation: AAC43195.1.
U01748 Genomic DNA. Translation: AAD10561.1.
RefSeqiNP_072771.2. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC71327; AAC71327; MG_109.
GeneIDi875289.
KEGGimge:MG_109.
PATRICi20009622. VBIMycGen98045_0120.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71327.1. Different initiation.
U01720 Unassigned DNA. Translation: AAC43195.1.
U01748 Genomic DNA. Translation: AAD10561.1.
RefSeqiNP_072771.2. NC_000908.2.

3D structure databases

ProteinModelPortaliP47355.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243273.MG_109.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC71327; AAC71327; MG_109.
GeneIDi875289.
KEGGimge:MG_109.
PATRICi20009622. VBIMycGen98045_0120.

Phylogenomic databases

eggNOGiCOG0515.
KOiK08884.
OMAiTDENSLF.
OrthoDBiEOG62NX1C.

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-113-MONOMER.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.
  2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
    Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
    J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 143-262 AND 286-376.
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiPKNS_MYCGE
AccessioniPrimary (citable) accession number: P47355
Secondary accession number(s): Q49450
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: November 1, 1997
Last modified: January 7, 2015
This is version 93 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.