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P47355

- PKNS_MYCGE

UniProt

P47355 - PKNS_MYCGE

Protein

Putative serine/threonine-protein kinase

Gene

MG109

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 2 (01 Nov 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei164 – 1641Proton acceptorPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMGEN243273:GH2R-113-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative serine/threonine-protein kinase (EC:2.7.11.1)
    Gene namesi
    Ordered Locus Names:MG109
    OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
    Taxonomic identifieri243273 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000000807: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 387387Putative serine/threonine-protein kinasePRO_0000171201Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243273.MG_109.

    Structurei

    3D structure databases

    ProteinModelPortaliP47355.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini15 – 344330Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    KOiK08884.
    OMAiTDENSLF.
    OrthoDBiEOG62NX1C.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P47355-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEAILKIGDI VENKYQIEKL LNRGGMDSYL FLAKNLNLKN YGPVQKKQYG    50
    HLVLKVVQKN PKINENNWKK FLDEMVTTTR VHHSNLVKSF DVVNPFLKIV 100
    RGNKTIALNQ IVMIAMEYVD GPSLRQLLNR KGYFSVSEVV YYFTKIVKAI 150
    DYLHSFKHQI IHRDLKPENI LFTSDLTDIK LLDFGIASTV VKVAEKTEVL 200
    TDENSLFGTV SYMIPDVLES TVNKAGKKVR KPPNAQYDIY SLGIILFEML 250
    VGRVPFNKSI NPNKERETIQ KARNFDLPLM QATRSDIPNS LENIAFRCTA 300
    VKRENNKWLY SSTKELLEDL ANWENEQAMI KPANERVLEG QVEIREMMLE 350
    KPLAWYFKTW ALSIFTIVFI GLIIAAIVLL LIFNARF 387
    Length:387
    Mass (Da):44,626
    Last modified:November 1, 1997 - v2
    Checksum:i346D35DDF2C15610
    GO

    Sequence cautioni

    The sequence AAC71327.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L43967 Genomic DNA. Translation: AAC71327.1. Different initiation.
    U01720 Unassigned DNA. Translation: AAC43195.1.
    U01748 Genomic DNA. Translation: AAD10561.1.
    RefSeqiNP_072771.2. NC_000908.2.

    Genome annotation databases

    EnsemblBacteriaiAAC71327; AAC71327; MG_109.
    GeneIDi875289.
    KEGGimge:MG_109.
    PATRICi20009622. VBIMycGen98045_0120.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L43967 Genomic DNA. Translation: AAC71327.1 . Different initiation.
    U01720 Unassigned DNA. Translation: AAC43195.1 .
    U01748 Genomic DNA. Translation: AAD10561.1 .
    RefSeqi NP_072771.2. NC_000908.2.

    3D structure databases

    ProteinModelPortali P47355.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243273.MG_109.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC71327 ; AAC71327 ; MG_109 .
    GeneIDi 875289.
    KEGGi mge:MG_109.
    PATRICi 20009622. VBIMycGen98045_0120.

    Phylogenomic databases

    eggNOGi COG0515.
    KOi K08884.
    OMAi TDENSLF.
    OrthoDBi EOG62NX1C.

    Enzyme and pathway databases

    BioCyci MGEN243273:GH2R-113-MONOMER.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33530 / G-37 / NCTC 10195.
    2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
      Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
      J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 143-262 AND 286-376.
      Strain: ATCC 33530 / G-37 / NCTC 10195.

    Entry informationi

    Entry nameiPKNS_MYCGE
    AccessioniPrimary (citable) accession number: P47355
    Secondary accession number(s): Q49450
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: November 1, 1997
    Last modified: October 1, 2014
    This is version 92 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Mycoplasma genitalium
      Mycoplasma genitalium (strain G-37): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3