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P47346

- GATB_MYCGE

UniProt

P47346 - GATB_MYCGE

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Protein

Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B

Gene

gatB

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).By similarity

Catalytic activityi

ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.
ATP + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + phosphate + L-asparaginyl-tRNA(Asn) + L-glutamate.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. carbon-nitrogen ligase activity, with glutamine as amido-N-donor Source: InterPro

GO - Biological processi

  1. translation Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-103-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (EC:6.3.5.-)
Short name:
Asp/Glu-ADT subunit B
Gene namesi
Name:gatB
Ordered Locus Names:MG100
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 477477Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit BPRO_0000148807Add
BLAST

Proteomic databases

PRIDEiP47346.

Interactioni

Subunit structurei

Heterotrimer of A, B and C subunits.By similarity

Protein-protein interaction databases

STRINGi243273.MG_100.

Structurei

3D structure databases

ProteinModelPortaliP47346.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GatB/GatE family. GatB subfamily.Curated

Phylogenomic databases

eggNOGiCOG0064.
KOiK02434.
OMAiAIDYEES.
OrthoDBiEOG6RJV5B.

Family and domain databases

HAMAPiMF_00121. GatB.
InterProiIPR004413. Apn/Gln-ADT_bsu.
IPR017959. Asn/Gln-tRNA_amidoTrfase_suB/E.
IPR006075. Asn/Gln-tRNA_Trfase_suB/E_cat.
IPR018027. Asn/Gln_amidotransferase.
IPR003789. Asn/Gln_tRNA_amidoTrfrase-rel.
IPR017958. Gln-tRNA_amidoTrfase_suB_CS.
[Graphical view]
PANTHERiPTHR11659. PTHR11659. 1 hit.
PfamiPF02934. GatB_N. 1 hit.
PF02637. GatB_Yqey. 1 hit.
[Graphical view]
SMARTiSM00845. GatB_Yqey. 1 hit.
[Graphical view]
SUPFAMiSSF89095. SSF89095. 1 hit.
TIGRFAMsiTIGR00133. gatB. 1 hit.
PROSITEiPS01234. GATB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47346-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MINFEAIIGI EVHVVLNTAS KMFSKAPNRV DNQKINHFID PIDLGLPGTL
60 70 80 90 100
PQVNELAVYK ALLLADALKM KTVTNKLVFD RKHYFYQDLP KGFQITQQNY
110 120 130 140 150
PFAKNGVVTI NVDAIEKPIY IDRFHLEEDT AKQHFNHDQI LLDFNRCGAP
160 170 180 190 200
LIEVVTLPVI NTAKEAKAYL QKLRQILIVN NISNAKLEDG SMRSDCNVSV
210 220 230 240 250
RLKGQRQLGT KIEIKNINSL NNVEKAIDLE INRQVKALIN GETLSQATLS
260 270 280 290 300
FDDKTNNNVF MRKKDNTIDY RYFIEPNIMT SNIDDLLLEK PVAFQLEQFQ
310 320 330 340 350
KELIDSNVNP QLVQLVVDDA TIFSAFQTIN SVIKNPQETI RWLCIELIGQ
360 370 380 390 400
LNKTNSSLTA NLIQDLITLI EMLKAAKVNQ KQAKQLITLM IETKKDPKSL
410 420 430 440 450
AKLHNLEQIT DPKELQKIIK KIFQENEKEI LKNIDRIERI QKLIIGQVMH
460 470
KTNNRANPQQ VFIIVENMLH EVRERDS
Length:477
Mass (Da):54,695
Last modified:February 1, 1996 - v1
Checksum:iE8A05FA097913D96
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71318.1.
U01799 Genomic DNA. Translation: AAD12325.1.
PIRiA64211.
RefSeqiNP_072762.1. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC71318; AAC71318; MG_100.
GeneIDi875247.
KEGGimge:MG_100.
PATRICi20009602. VBIMycGen98045_0110.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71318.1 .
U01799 Genomic DNA. Translation: AAD12325.1 .
PIRi A64211.
RefSeqi NP_072762.1. NC_000908.2.

3D structure databases

ProteinModelPortali P47346.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243273.MG_100.

Proteomic databases

PRIDEi P47346.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC71318 ; AAC71318 ; MG_100 .
GeneIDi 875247.
KEGGi mge:MG_100.
PATRICi 20009602. VBIMycGen98045_0110.

Phylogenomic databases

eggNOGi COG0064.
KOi K02434.
OMAi AIDYEES.
OrthoDBi EOG6RJV5B.

Enzyme and pathway databases

BioCyci MGEN243273:GH2R-103-MONOMER.

Family and domain databases

HAMAPi MF_00121. GatB.
InterProi IPR004413. Apn/Gln-ADT_bsu.
IPR017959. Asn/Gln-tRNA_amidoTrfase_suB/E.
IPR006075. Asn/Gln-tRNA_Trfase_suB/E_cat.
IPR018027. Asn/Gln_amidotransferase.
IPR003789. Asn/Gln_tRNA_amidoTrfrase-rel.
IPR017958. Gln-tRNA_amidoTrfase_suB_CS.
[Graphical view ]
PANTHERi PTHR11659. PTHR11659. 1 hit.
Pfami PF02934. GatB_N. 1 hit.
PF02637. GatB_Yqey. 1 hit.
[Graphical view ]
SMARTi SM00845. GatB_Yqey. 1 hit.
[Graphical view ]
SUPFAMi SSF89095. SSF89095. 1 hit.
TIGRFAMsi TIGR00133. gatB. 1 hit.
PROSITEi PS01234. GATB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.
  2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
    Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
    J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 80-177.
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiGATB_MYCGE
AccessioniPrimary (citable) accession number: P47346
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: October 1, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3