ID RL11_MYCGE Reviewed; 137 AA. AC P47327; DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot. DT 23-JAN-2007, sequence version 2. DT 27-MAR-2024, entry version 124. DE RecName: Full=Large ribosomal subunit protein uL11 {ECO:0000255|HAMAP-Rule:MF_00736}; DE AltName: Full=50S ribosomal protein L11 {ECO:0000305}; GN Name=rplK {ECO:0000255|HAMAP-Rule:MF_00736}; GN Synonyms=rpl11 {ECO:0000255|HAMAP-Rule:MF_00736}; GN OrderedLocusNames=MG081; OS Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) OS (Mycoplasmoides genitalium). OC Bacteria; Mycoplasmatota; Mycoplasmoidales; Mycoplasmoidaceae; OC Mycoplasmoides. OX NCBI_TaxID=243273; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37; RX PubMed=7569993; DOI=10.1126/science.270.5235.397; RA Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., RA Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., RA Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., RA Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M., RA Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., RA Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.; RT "The minimal gene complement of Mycoplasma genitalium."; RL Science 270:397-403(1995). CC -!- FUNCTION: Forms part of the ribosomal stalk which helps the ribosome CC interact with GTP-bound translation factors. {ECO:0000255|HAMAP- CC Rule:MF_00736}. CC -!- SUBUNIT: Part of the ribosomal stalk of the 50S ribosomal subunit. CC Interacts with L10 and the large rRNA to form the base of the stalk. CC L10 forms an elongated spine to which L12 dimers bind in a sequential CC fashion forming a multimeric L10(L12)X complex. {ECO:0000255|HAMAP- CC Rule:MF_00736}. CC -!- PTM: One or more lysine residues are methylated. {ECO:0000255|HAMAP- CC Rule:MF_00736}. CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL11 family. CC {ECO:0000255|HAMAP-Rule:MF_00736}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; L43967; AAC71299.1; -; Genomic_DNA. DR PIR; I64208; I64208. DR RefSeq; WP_009885638.1; NZ_AAGX01000002.1. DR AlphaFoldDB; P47327; -. DR SMR; P47327; -. DR STRING; 243273.MG_081; -. DR KEGG; mge:MG_081; -. DR eggNOG; COG0080; Bacteria. DR HOGENOM; CLU_074237_2_2_14; -. DR InParanoid; P47327; -. DR OrthoDB; 9802408at2; -. DR BioCyc; MGEN243273:G1GJ2-93-MONOMER; -. DR Proteomes; UP000000807; Chromosome. DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central. DR GO; GO:0070180; F:large ribosomal subunit rRNA binding; IBA:GO_Central. DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central. DR GO; GO:0006412; P:translation; IBA:GO_Central. DR CDD; cd00349; Ribosomal_L11; 1. DR Gene3D; 1.10.10.250; Ribosomal protein L11, C-terminal domain; 1. DR Gene3D; 3.30.1550.10; Ribosomal protein L11/L12, N-terminal domain; 1. DR HAMAP; MF_00736; Ribosomal_uL11; 1. DR InterPro; IPR000911; Ribosomal_uL11. DR InterPro; IPR006519; Ribosomal_uL11_bac-typ. DR InterPro; IPR020783; Ribosomal_uL11_C. DR InterPro; IPR036769; Ribosomal_uL11_C_sf. DR InterPro; IPR020785; Ribosomal_uL11_CS. DR InterPro; IPR020784; Ribosomal_uL11_N. DR InterPro; IPR036796; Ribosomal_uL11_N_sf. DR NCBIfam; TIGR01632; L11_bact; 1. DR PANTHER; PTHR11661:SF1; 39S RIBOSOMAL PROTEIN L11, MITOCHONDRIAL; 1. DR PANTHER; PTHR11661; 60S RIBOSOMAL PROTEIN L12; 1. DR Pfam; PF00298; Ribosomal_L11; 1. DR Pfam; PF03946; Ribosomal_L11_N; 1. DR SMART; SM00649; RL11; 1. DR SUPFAM; SSF54747; Ribosomal L11/L12e N-terminal domain; 1. DR SUPFAM; SSF46906; Ribosomal protein L11, C-terminal domain; 1. DR PROSITE; PS00359; RIBOSOMAL_L11; 1. PE 3: Inferred from homology; KW Methylation; Reference proteome; Ribonucleoprotein; Ribosomal protein; KW RNA-binding; rRNA-binding. FT INIT_MET 1 FT /note="Removed" FT /evidence="ECO:0000250" FT CHAIN 2..137 FT /note="Large ribosomal subunit protein uL11" FT /id="PRO_0000104317" SQ SEQUENCE 137 AA; 14735 MW; A5DD5E6C4CD66E33 CRC64; MAKKTVTRIA KINLIGGQAK PGPALASVGI NMGEFTKQFN EKTKDRQGET IPCIITAFND KSFTFVLKTT PVSNLIKQAA KLEKGAKNAK TIVGKISLQQ AKEIAQYKLV DLNANTVEAA LKMVLGTAKQ MGIEVTD //