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Protein

Ribosomal RNA small subunit methyltransferase I

Gene

rsmI

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + cytidine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytidine(1402) in 16S rRNA.UniRule annotation

GO - Molecular functioni

  1. rRNA (cytosine-2'-O-)-methyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. enzyme-directed rRNA 2'-O-methylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-58-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase IUniRule annotation (EC:2.1.1.198UniRule annotation)
Alternative name(s):
16S rRNA 2'-O-ribose C1402 methyltransferaseUniRule annotation
rRNA (cytidine-2'-O-)-methyltransferase RsmIUniRule annotation
Gene namesi
Name:rsmIUniRule annotation
Ordered Locus Names:MG056
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807 Componenti: Chromosome

Subcellular locationi

  1. Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 277277Ribosomal RNA small subunit methyltransferase IPRO_0000211943Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243273.MG_056.

Structurei

3D structure databases

ProteinModelPortaliP47302.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RsmI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0313.
KOiK07056.
OMAiKLHESHY.
OrthoDBiEOG6677TH.

Family and domain databases

Gene3Di3.30.950.10. 1 hit.
3.40.1010.10. 1 hit.
HAMAPiMF_01877. 16SrRNA_methyltr_I.
InterProiIPR000878. 4pyrrol_Mease.
IPR014777. 4pyrrole_Mease_sub1.
IPR014776. 4pyrrole_Mease_sub2.
IPR008189. rRNA_ssu_MeTfrase_I.
IPR018063. SAM_MeTrfase_RsmI_CS.
[Graphical view]
PfamiPF00590. TP_methylase. 1 hit.
[Graphical view]
PIRSFiPIRSF005917. MTase_YraL. 1 hit.
SUPFAMiSSF53790. SSF53790. 1 hit.
TIGRFAMsiTIGR00096. TIGR00096. 1 hit.
PROSITEiPS01296. RSMI. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47302-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTLKVVATP IGNIQEISER AKKALQDCEV LFCEDSRVTR KMLDLLNIDC
60 70 80 90 100
KQKKFVINNS FKEKQNLTFA EEFITNFKCC LVSDAGYPSL SDPGNEMINW
110 120 130 140 150
IISKNKEIRI EVINGPSALM CGLITSGFKT TPLLFLGFLS HKQNQLKNYL
160 170 180 190 200
STYQNQKSTI VFFEAVHRLE NTLETVKNVF KNNDVFIGRE LTKLHESHYW
210 220 230 240 250
FNTSENTLPD ITLKGEFVIV IDNQNINHQT LSSNQYLVYE IKKLMDIGVK
260 270
LKDACNYLAK KMHLKSSMLY TLFHESI
Length:277
Mass (Da):31,895
Last modified:February 1, 1996 - v1
Checksum:iCD25DD3930364B5C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71273.1.
PIRiB64206.
RefSeqiNP_072718.1. NC_000908.2.
WP_009885721.1. NZ_AAGX01000003.1.

Genome annotation databases

EnsemblBacteriaiAAC71273; AAC71273; MG_056.
KEGGimge:MG_056.
PATRICi20009494. VBIMycGen98045_0057.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC71273.1.
PIRiB64206.
RefSeqiNP_072718.1. NC_000908.2.
WP_009885721.1. NZ_AAGX01000003.1.

3D structure databases

ProteinModelPortaliP47302.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243273.MG_056.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC71273; AAC71273; MG_056.
KEGGimge:MG_056.
PATRICi20009494. VBIMycGen98045_0057.

Phylogenomic databases

eggNOGiCOG0313.
KOiK07056.
OMAiKLHESHY.
OrthoDBiEOG6677TH.

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-58-MONOMER.

Family and domain databases

Gene3Di3.30.950.10. 1 hit.
3.40.1010.10. 1 hit.
HAMAPiMF_01877. 16SrRNA_methyltr_I.
InterProiIPR000878. 4pyrrol_Mease.
IPR014777. 4pyrrole_Mease_sub1.
IPR014776. 4pyrrole_Mease_sub2.
IPR008189. rRNA_ssu_MeTfrase_I.
IPR018063. SAM_MeTrfase_RsmI_CS.
[Graphical view]
PfamiPF00590. TP_methylase. 1 hit.
[Graphical view]
PIRSFiPIRSF005917. MTase_YraL. 1 hit.
SUPFAMiSSF53790. SSF53790. 1 hit.
TIGRFAMsiTIGR00096. TIGR00096. 1 hit.
PROSITEiPS01296. RSMI. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiRSMI_MYCGE
AccessioniPrimary (citable) accession number: P47302
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: April 29, 2015
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.