Reviewed,
UniProtKB/Swiss-Prot P47299 (MANB_MYCGE)
Last modified
December 15, 2009.
Version 62.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Phosphomannomutase Short name=PMM EC=5.4.2.8 | ||||||
| Gene names |
| ||||||
| Organism | Mycoplasma genitalium [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 2097 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma |
Protein attributes
| Sequence length | 550 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | Alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. |
| Cofactor | Binds 1 magnesium ion per subunit By similarity. |
| Sequence similarities | Belongs to the phosphohexose mutase family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | Magnesium Metal-binding |
| Molecular function | Isomerase |
| PTM | Phosphoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro |
| Molecular function | magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphomannomutase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 550 | 550 | Phosphomannomutase | PRO_0000147828 | |||||
Sites | |||||||||
| Active site | 148 | 1 | Phosphoserine intermediate By similarity | ||||||
| Metal binding | 148 | 1 | Magnesium; via phosphate group By similarity | ||||||
| Metal binding | 300 | 1 | Magnesium By similarity | ||||||
| Metal binding | 302 | 1 | Magnesium By similarity | ||||||
| Metal binding | 304 | 1 | Magnesium By similarity | ||||||
Experimental info | |||||||||
| Sequence conflict | 42 – 46 | 5 | PLFGT → LYLAL in AAD12379. Ref.2 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. Venter J.C.Science 270:397-403(1995) [PubMed: 7569993] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195. |
| [2] | "A survey of the Mycoplasma genitalium genome by using random sequencing." Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III J. Bacteriol. 175:7918-7930(1993) [PubMed: 8253680] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-46. Strain: ATCC 33530 / G-37 / NCTC 10195. |
Cross-references
Sequence databases | |
|---|---|
| L43967 Genomic DNA. Translation: AAC71269.1. U02108 Genomic DNA. Translation: AAD12379.1. Different initiation. | |
| PIR | H64205. |
| RefSeq | NP_072713.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 875706. |
| KEGG | mge:MG_053. |
| TIGR | MG053. |
Phylogenomic databases | |
| HOGENOM | HBG571743. |
| OMA | IGEDVDM. |
Enzyme and pathway databases | |
| BioCyc | MGEN243273:MG_053-MON. |
| BRENDA | 5.4.2.8. 110. |
Family and domain databases | |
| InterPro | IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. [Graphical view] |
| Gene3D | G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 2 hits. |
| Pfam | PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view] |
| PRINTS | PR00509. PGMPMM. |
| PROSITE | PS00710. PGM_PMM. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | MANB_MYCGE | ||||||||
| Accession | Primary (citable) accession number: P47299 Secondary accession number(s): Q49247 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Mycoplasma genitalium Mycoplasma genitalium (strain G-37): entries and gene names |
| SIMILARITY comments Index of protein domains and families |

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