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P47299

- MANB_MYCGE

UniProt

P47299 - MANB_MYCGE

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Protein
Phosphomannomutase
Gene
manB, cpsG, MG053
Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.

Cofactori

Binds 1 magnesium ion per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei148 – 1481Phosphoserine intermediate By similarity
Metal bindingi148 – 1481Magnesium; via phosphate group By similarity
Metal bindingi300 – 3001Magnesium By similarity
Metal bindingi302 – 3021Magnesium By similarity
Metal bindingi304 – 3041Magnesium By similarity

GO - Molecular functioni

  1. magnesium ion binding Source: InterPro
  2. phosphomannomutase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-53-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphomannomutase (EC:5.4.2.8)
Short name:
PMM
Gene namesi
Name:manB
Synonyms:cpsG
Ordered Locus Names:MG053
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 550550Phosphomannomutase
PRO_0000147828Add
BLAST

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi243273.MG_053.

Structurei

3D structure databases

ProteinModelPortaliP47299.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1109.
KOiK01840.
OMAiFACEESH.
OrthoDBiEOG6103ZG.

Family and domain databases

Gene3Di3.30.310.50. 1 hit.
3.40.120.10. 3 hits.
InterProiIPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016066. A-D-PHexomutase_CS.
IPR005841. Alpha-D-phosphohexomutase_SF.
[Graphical view]
PfamiPF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view]
PRINTSiPR00509. PGMPMM.
SUPFAMiSSF53738. SSF53738. 3 hits.
SSF55957. SSF55957. 1 hit.
PROSITEiPS00710. PGM_PMM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47299-1 [UniParc]FASTAAdd to Basket

« Hide

MDKLRLEVER WLNHPNVNWE LKQQIKELNE SEIQELFSLE KPLFGTAGVR    50
NKMAPGYHGM NVFSYAYLTQ GYVKYIESIN EPKRQLRFLV ARDTRKNGGL 100
FLETVCDVIT SMGHLAYVFD DNQPVSTPLV SHVIFKYGFS GGINITASHN 150
PKDDNGFKVY DHTGAQLLDT QTNQLLSDLP CVTSMLDLEL QPNPKFVHTL 200
DNEKVYKNYF RELKKVLVIN NNNFKDIKVV FSGLNGTSVC LMQRFLKYLG 250
YSNIISVEEQ NWFDENFENA PNLNPEYKDT WILAQKYAKK NNAKLIIMAD 300
PDADRFAIAE LNNNQWHYFS GNETGAITAY YKLNHKVFKS PYIVSTFVST 350
YLVNKIAKRY GAFVHRTNVG FKYIGQAINE LSQTNELVVG FEEAIGLITS 400
DKLNREKDAY QAAALLLEIA RHCKEQNITL LDFYKRILSE FGEYFNLTIS 450
HPFKATATDW KEEIKALFNQ LINANLTEVA GFKVVKVHLD KQTNILEFGF 500
ENGWVKFRFS GTEPKLKFYF DLTNGTREAL EKQAKKIYKF FVNLLKLNKA 550
Length:550
Mass (Da):63,397
Last modified:February 1, 1996 - v1
Checksum:iD7BDF8920923508D
GO

Sequence cautioni

The sequence AAD12379.1 differs from that shown. Reason: Erroneous initiation.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti42 – 465PLFGT → LYLAL in AAD12379. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43967 Genomic DNA. Translation: AAC71269.1.
U02108 Genomic DNA. Translation: AAD12379.1. Different initiation.
PIRiH64205.
RefSeqiNP_072713.1. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC71269; AAC71269; MG_053.
GeneIDi875706.
KEGGimge:MG_053.
PATRICi20009486. VBIMycGen98045_0053.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43967 Genomic DNA. Translation: AAC71269.1 .
U02108 Genomic DNA. Translation: AAD12379.1 . Different initiation.
PIRi H64205.
RefSeqi NP_072713.1. NC_000908.2.

3D structure databases

ProteinModelPortali P47299.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243273.MG_053.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC71269 ; AAC71269 ; MG_053 .
GeneIDi 875706.
KEGGi mge:MG_053.
PATRICi 20009486. VBIMycGen98045_0053.

Phylogenomic databases

eggNOGi COG1109.
KOi K01840.
OMAi FACEESH.
OrthoDBi EOG6103ZG.

Enzyme and pathway databases

BioCyci MGEN243273:GH2R-53-MONOMER.

Family and domain databases

Gene3Di 3.30.310.50. 1 hit.
3.40.120.10. 3 hits.
InterProi IPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016066. A-D-PHexomutase_CS.
IPR005841. Alpha-D-phosphohexomutase_SF.
[Graphical view ]
Pfami PF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view ]
PRINTSi PR00509. PGMPMM.
SUPFAMi SSF53738. SSF53738. 3 hits.
SSF55957. SSF55957. 1 hit.
PROSITEi PS00710. PGM_PMM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.
  2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
    Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
    J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-46.
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiMANB_MYCGE
AccessioniPrimary (citable) accession number: P47299
Secondary accession number(s): Q49247
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: May 14, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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