P47295 (DEOD_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Purine nucleoside phosphorylase deoD-type
Short name=PNP
EC=2.4.2.1

Gene names

Name:	deoD
Ordered Locus Names:	MG049

Organism

Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]

Taxonomic identifier

243273 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	238 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. HAMAP MF_01627
Subunit structure	Homohexamer By similarity. HAMAP MF_01627
Sequence similarities	Belongs to the PNP/UDP phosphorylase family.
Sequence caution	The sequence AAC71265.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nucleoside metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	purine-nucleoside phosphorylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 238	238	Purine nucleoside phosphorylase deoD-type HAMAP MF_01627		PRO_0000063146

Sequences

	Sequence		Length	Mass (Da)
	P47295 [UniParc]. Last modified November 1, 1997. Version 2. Checksum: C3B3523FEBBB806A	FASTA	238	26,509
	10 20 30 40 50 60 MTPHISAKKD DISKVVLMPG DPLRAKWIAE QFLDQAKLVN EVRGMFAYTG QYKSKTVTVM 70 80 90 100 110 120 GHGMGIPSIG IYSYELMNFY EVETIIRIGS CGALAPQLKL KDLVIASKAW SESIYAKDMG 130 140 150 160 170 180 VEIPEDKILF ATSSLVELAK ETAIKNKLDF HEGLVFCEDA FYQTRKDVIS LAKEKNSLAV 190 200 210 220 230 EMEAHALYAN AILLKKKALT LLTVSDSLVT HEALSSELRQ KSFKQMALLA LEMTQKLI

References

[1]

"The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. , Phillips C.A., Merrick J.M., Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C. Science 270:397-403(1995) [PubMed: 7569993] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L43967 Genomic DNA. Translation: AAC71265.1. Different initiation.
PIR	D64205.
RefSeq	NP_072709.2. NC_000908.2.
3D structure databases
ProteinModelPortal	P47295.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	875267.
GenomeReviews	Gene locus MG049 in contig L43967_GR.
KEGG	mge:MG_049.
PATRIC	20009478. VBIMycGen98045_0049.
TIGR	MG049.
Phylogenomic databases
HOGENOM	HBG617197.
OMA	EPEIFEK.
PhylomeDB	P47295.
ProtClustDB	PRK05819.
Enzyme and pathway databases
BioCyc	MGEN243273:MG_049-MONOMER.
Family and domain databases
HAMAP	MF_01627. Pur_nucleosid_phosp. [Tree]
InterPro	IPR004402. DeoD. IPR018017. Nucleoside_phosphorylase. IPR018016. Nucleoside_phosphorylase_CS. IPR000845. Nucleoside_phosphorylase_d. [Graphical view]
KO	K03784.
PANTHER	PTHR21234. PNP_UDP. 1 hit.
Pfam	PF01048. PNP_UDP_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR00107. DeoD. 1 hit.
PROSITE	PS01232. PNP_UDP_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DEOD_MYCGE

Accession

Primary (citable) accession number: P47295

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	November 1, 1997
Last modified:	January 25, 2012
This is version 66 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program