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P47295 (DEOD_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Purine nucleoside phosphorylase DeoD-type

Short name=PNP
EC=2.4.2.1
Gene names
Name:deoD
Ordered Locus Names:MG049
OrganismMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]
Taxonomic identifier243273 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length238 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Subunit structure

Homohexamer By similarity. HAMAP-Rule MF_01627

Sequence similarities

Belongs to the PNP/UDP phosphorylase family.

Sequence caution

The sequence AAC71265.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processnucleoside metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionpurine-nucleoside phosphorylase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 238238Purine nucleoside phosphorylase DeoD-type HAMAP-Rule MF_01627
PRO_0000063146

Sequences

Sequence LengthMass (Da)Tools
P47295 [UniParc].

Last modified November 1, 1997. Version 2.
Checksum: C3B3523FEBBB806A

FASTA23826,509
        10         20         30         40         50         60 
MTPHISAKKD DISKVVLMPG DPLRAKWIAE QFLDQAKLVN EVRGMFAYTG QYKSKTVTVM 

        70         80         90        100        110        120 
GHGMGIPSIG IYSYELMNFY EVETIIRIGS CGALAPQLKL KDLVIASKAW SESIYAKDMG 

       130        140        150        160        170        180 
VEIPEDKILF ATSSLVELAK ETAIKNKLDF HEGLVFCEDA FYQTRKDVIS LAKEKNSLAV 

       190        200        210        220        230 
EMEAHALYAN AILLKKKALT LLTVSDSLVT HEALSSELRQ KSFKQMALLA LEMTQKLI 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L43967 Genomic DNA. Translation: AAC71265.1. Different initiation.
PIRD64205.
RefSeqNP_072709.2. NC_000908.2.

3D structure databases

ProteinModelPortalP47295.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243273.MG_049.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC71265; AAC71265; MG_049.
GeneID875267.
KEGGmge:MG_049.
PATRIC20009478. VBIMycGen98045_0049.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0813.
KOK03784.
OMASFETHAF.
OrthoDBEOG6BKJC5.
ProtClustDBPRK05819.

Enzyme and pathway databases

BioCycMGEN243273:GH2R-49-MONOMER.

Family and domain databases

Gene3D3.40.50.1580. 1 hit.
HAMAPMF_01627. Pur_nucleosid_phosp.
InterProIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERPTHR21234. PTHR21234. 1 hit.
PfamPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMSSF53167. SSF53167. 1 hit.
TIGRFAMsTIGR00107. deoD. 1 hit.
PROSITEPS01232. PNP_UDP_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDEOD_MYCGE
AccessionPrimary (citable) accession number: P47295
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: November 1, 1997
Last modified: April 16, 2014
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma genitalium

Mycoplasma genitalium (strain G-37): entries and gene names