P47292 (GCP_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	MG046

Organism

Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]

Taxonomic identifier

243273 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Tenericutes › Mollicutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma genitalium

Protein attributes

Sequence length	315 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP-Rule MF_01445
Subcellular location	Cytoplasm Potential HAMAP-Rule MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	threonylcarbamoyladenosine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 315	315	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP-Rule MF_01445		PRO_0000096967

Sequences

	Sequence		Length	Mass (Da)
	P47292 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: D186ECD176C4E574	FASTA	315	34,708
	10 20 30 40 50 60 MEQPLCVLGI ETTCDDTGLS IVIDQKIKSN IVISSANLHV KTGGVVPEIA ARCHEQNLFK 70 80 90 100 110 120 AIRDLNFEIR DLSHIAYACN PGLAGCLHVG ATFARSLSFL LDKPLLPINH LYAHIFSCLI 130 140 150 160 170 180 DQDLNKLQLP ALGLVISGGH TAIYLVKSFY ELELIAETSD DAIGEVYDKI GRAMGFDYPA 190 200 210 220 230 240 GSKIDSLFNK ELVKPHYFFK PSTKWTKFSY SGLKSQCLNK IKQISANKTR IDWSELASNF 250 260 270 280 290 300 QATIIDHYID HVKNAIKKFA PKMLLVGGGV SANSYLSNRI STLNLPFLIA DSKYTSDNGA 310 MIGFYASLLI NGDKN

References

[1]

"The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. , Phillips C.A., Merrick J.M., Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C. Science 270:397-403(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L43967 Genomic DNA. Translation: AAC71262.1.
PIR	A64205.
RefSeq	NP_072706.1. NC_000908.2.
3D structure databases
ProteinModelPortal	P47292.
ModBase	Search...
Protein-protein interaction databases
STRING	243273.MG_046.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC71262; AAC71262; MG_046.
GeneID	875433.
KEGG	mge:MG_046.
PATRIC	20009470. VBIMycGen98045_0045.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0533.
KO	K01409.
OMA	AVHHMEG.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	MGEN243273:GH2R-85-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp.
InterPro	IPR000905. Gcp-like_dom. IPR017861. KAE1/YgjD. IPR017860. Peptidase_M22_CS. IPR022450. T6A_Gcp_(YgjD). [Graphical view]
PANTHER	PTHR11735:SF6. PTHR11735:SF6. 1 hit.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. bact_gcp. 1 hit. TIGR00329. gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_MYCGE

Accession

Primary (citable) accession number: P47292

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	May 1, 2013
This is version 84 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program